Results 101 to 110 of about 9,088 (303)
FEBS Open Bio, EarlyView.In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source
The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity
FEBS Open Bio, EarlyView.Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav +4 more
wiley +1 more source
The GacSA-RetS-PA1611-LadS signaling network.
, 2016 (A) Current model for the regulatory elements influencing the expression of two sRNAs, RsmY and RsmZ. See text for details. (B) The multicomponent signal transduction system made of the LadS hybrid HK and the GacS/GacA TCS.
David Redelberger (1697776) +7 more
core +1 more source
Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling
FEBS Open Bio, EarlyView.Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt +2 more
wiley +1 more source
mBioPseudomonas aeruginosa is one of the most common nosocomial pathogens worldwide, known for its virulence, drug resistance, and elaborate sensor-response network. The primary challenge encountered by pathogens during the initial stages of infection is the
Xiaolong Guo +9 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou +16 more
wiley +1 more source
Names of boys under the Farm Lads migration scheme. Names are taken from correspondence between the Immigration Agent and prospective employers, farm learners (farm lads) and parents regarding possible employment or the boys' placement on farms: [S5384](
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, 1916 The conquerors: The spy. The atrocity. Ballad of the Germans. The steam roller. My experience with Baedeker.--Golden lads: The play-boys of Brittany. "Enchanted cigarettes." Was it real? "Chantons, Belges! Chantons." Flies: a fantasy.
Gleason, Arthur, 1878-1923. +1 more
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From Theory to Interface: Operationalising Frameworks in the Design of Learning Analytics Dashboards
Advances in Human-Computer InteractionLearning analytics dashboards (LADs) have been widely adopted in higher education to support academic engagement and provide pedagogical interventions.
Anthony Kingsley Sackey +2 more
doaj +1 more source
Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro +6 more
wiley +1 more source