Results 41 to 50 of about 88,672,115 (295)
Lymphocyte Activation Gene 3 (LAG-3) modulates the ability of CD4 T-cells to be suppressed in vivo. [PDF]
PLoS ONE, 2014 Lymphocyte Activation Gene - 3 (LAG-3) is an immune checkpoint molecule that regulates both T-cell activation and homeostasis. However, the molecular mechanisms underlying LAG-3's function are generally unknown.
Nicholas M Durham +6 more
doaj +1 more source
Клиническая онкогематологияAIM. To analyze the bone marrow lymphocyte subpopulation based on targeted assessment of PD-1, PD-L1, and LAG-3 marker expression in chronic lymphocytic leukemia (CLL) patients with different responses to chemotherapy. MATERIALS & METHODS.
Olesya Nikolaevna Selyutina +7 more
doaj +1 more source
Modulation of CTLA-4, STAT3 and LAG-3 Expression by Ibrutinib and Idelalisib in Leukemic Cells of Patients with Chronic Lymphocytic Leukemia [PDF]
Middle East Journal of CancerBackground: Small molecule inhibitors are the new therapeutic approaches for many cancers, but their exact mechanisms in tumor evasion and expansion remains unknown.
Fatemeh Mousavi-Mirkalaei +9 more
doaj +1 more source
Role of lymphocyte activation gene-3 (Lag-3) in conventional and regulatory T cell function in allogeneic transplantation. [PDF]
PLoS ONE, 2014 Lag-3 has emerged as an important molecule in T cell biology. We investigated the role of Lag-3 in conventional T cell (Tcon) and regulatory T cell (Treg) function in murine GVHD with the hypothesis that Lag-3 engagement diminishes alloreactive T cell ...
Emanuela I Sega +5 more
doaj +1 more source
Cancer Medicine, 2023 Background Lymphocyte activation gene 3 (LAG‐3) or CD223 is a transmembrane protein that serves as an immune checkpoint which attenuates T‐cell activation.
Jacob J. Adashek +11 more
doaj +1 more source
Frontiers in Immunology, 2021 BackgroundTransarterial chemoembolization (TACE) stands for the most commonly utilized therapy for hepatocellular carcinoma (HCC) worldwide. This study was to explore the potential predictive and prognostic roles of LAG-3 and PD-L1 as serum biomarkers in
Mengzhou Guo +7 more
doaj +1 more source
LAG-1 applied to an example visual search problem.
, 2022 A) Visual Field input array recreated from [53]. B) An example trial of LAG-1’s visual search scan path. Each frame is centered at the successive fixation location until the target is foveated.
Mark R. Blair (11846177) +3 more
core +1 more source
Referral Patterns and Diagnostic Timeliness in Pediatric Cancer: A Hospital‐Based Study in Indonesia
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Timely diagnosis and treatment are critical for improving survival among children with cancer. In low‐ and middle‐income countries (LMICs), delays are common and may be influenced by fragmented referral pathways and diagnostic limitations.
Nur Melani Sari +5 more
wiley +1 more source