Results 141 to 150 of about 96,178 (343)

OGT (O-GlcNAc Transferase) Selectively Modifies Multiple Residues Unique to Lamin A

Cells, 2018
The LMNA gene encodes lamins A and C with key roles in nuclear structure, signaling, gene regulation, and genome integrity. Mutations in LMNA cause over 12 diseases (‘laminopathies’). Lamins A and C are identical for their first 566 residues.
Dan N. Simon, Amanda Wriston, Qiong Fan, Jeffrey Shabanowitz, Alyssa Florwick, Tejas Dharmaraj, Sherket B. Peterson, Yosef Gruenbaum, Cathrine R. Carlson, Line M. Grønning-Wang, Donald F. Hunt, Katherine L. Wilson   +11 more
doaj   +1 more source

Involvement of Lamin B1 Reduction in Accelerated Cellular Senescence during Chronic Obstructive Pulmonary Disease Pathogenesis

Journal of Immunology, 2019
Downregulation of lamin B1 has been recognized as a crucial step for development of full senescence. Accelerated cellular senescence linked to mechanistic target of rapamycin kinase (MTOR) signaling and accumulation of mitochondrial damage has been ...
Nayuta Saito, J. Araya, Saburo Ito, K. Tsubouchi, S. Minagawa, Hiromichi Hara, A. Ito, Takayuki Nakano, Yusuke Hosaka, Akihiro Ichikawa, T. Kadota, Masahiro Yoshida, Y. Fujita, H. Utsumi, Yusuke Kurita, Kenji Kobayashi, Mitsuo Hashimoto, H. Wakui, T. Numata, Y. Kaneko, H. Asano, M. Odaka, T. Ohtsuka, T. Morikawa, K. Nakayama, K. Kuwano   +25 more
semanticscholar   +1 more source

Neuronal Lamin regulates motor circuit integrity and controls motor function and lifespan

Cell Stress, 2018
Neuronal aging involves a progressive decline in cognitive abilities and loss of motor function. Mutations in human Lamin genes (LMNA, LMNB1, LMNB2) lead to a wide-range of diseases including muscular dystrophy, peripheral neuropathy and progeria.
Lisa J. Oyston, Yong Qi Lin, Thang M. Khuong, Qiao-Ping Wang, Man Tat Lau, Teleri Clark, G. Gregory Neely   +6 more
doaj   +1 more source

Selenoproteins in mammalian spermatogenesis:role of the nuclear GPx4 [PDF]

, 2011
The selenoprotein Phospholipid Hydroperoxide Glutathione Peroxidase (PHGPx/GPx4) is an enzyme unique among the various GPxs, because it is able to use protein thiols, beside glutathione, The GPx4 gene encodes for three isoforms having different ...
Maccari, Irene
core  

Temporal Changes in Nucleus Morphology, Lamin A/C and Histone Methylation During Nanotopography-Induced Neuronal Differentiation of Stem Cells [PDF]

, 2018
Soneela Ankam, Benjamin K. K. Teo, Grace Pohan, Shawn W. L. Ho, Choon Kiat Lim, Evelyn K. F. Yim   +5 more
openalex   +1 more source

Supplementary Figures from Lamin B1 Is a Novel Therapeutic Target of Betulinic Acid in Pancreatic Cancer

, 2023
Lei Li, Yiqi Du, Xiangyu Kong, Zhaoshen Li, Zhiliang Jia, Jiujie Cui, Jun Gao, Guokun Wang, Keping Xie   +8 more
openalex   +1 more source

Nuclear Entanglement: New Insights Into the Role of Cytoskeleton and Nucleoskeleton in Plant Nuclear Function

Cytoskeleton, EarlyView.
ABSTRACT Of the three types of cytoskeleton known in animals—actin, microtubules, and intermediate filaments—only actin and microtubules exist in plants. Both play important roles in cellular shaping, organelle movement, organization of the endomembrane system, and cell signaling.
Norman R. Groves, Katelyn Amstutz, Lily A. Schumacher, Iris Meier   +3 more
wiley   +1 more source

Journal of African Christian Biography: v. 2, no. 3 [PDF]

, 2017
A publication of the Dictionary of African Christian Biography with U.S. offices located at the Center for Global Christianity and Mission at Boston University. This issue focuses on: 1. Agnes Okoh. 2. Self-Sacrificial Christian Pioneers of Uganda.
Bonk, Jonathan J., Byaruhanga, Christopher, Kalengyo, Edison Muhindo, Oduro, Thomas, Tumwine, John Kateeba, Way, Yossa   +5 more
core  

Titin Is Present in the Elastic Tethers That Connect Separating Anaphase Chromosomes in Crane‐Fly Spermatocytes

Cytoskeleton, EarlyView.
ABSTRACT Elastic tethers connect telomeres of separating chromosomes in anaphase of animal cells. Immunofluorescence staining of titin in crane‐fly spermatocytes, using 4 different antibodies, shows that the giant elastic protein titin seems to be a component of mitotic tethers: titin “strands” extend between separating chromosomes, connecting their ...
Demetra Economopoulos, Maral Janan, Martina Krüger, Aavo‐Valdur Mikelsaar, Arthur Forer, Rose Sheykhani   +5 more
wiley   +1 more source

Os efeitos da não atualização da tabela progressiva no bolso do contribuinte pessoa física. [PDF]

, 2017
TCC (Graduação) - Universidade Federal de Santa Catarina. Centro Socioeconômico. Curso de Ciências ContábeisO Imposto de Renda de Pessoa Física, gera motivos para discussões no que se refere a uma revisão total de suas regras, suas alíquotas e a ...
Lamin, Mayara
core