Results 151 to 160 of about 43,097 (243)

GRWD1 enhances HSV-1 replication by facilitating nuclear egress. [PDF]

Microbiol Spectr
Kong Z, Gao C, Liu X, Xue T, Liang X, Yan P, Zhang R, Tang J.   +7 more
europepmc   +1 more source

Resistance‐exercise‐induced stress intervenes in TGF‐β signaling by cooperatively downregulating nuclear αB‐crystallin and SMAD4 in human skeletal muscle fibers

The FEBS Journal, Volume 293, Issue 15, Page 4624-4644, August 2026.
Alpha‐crystallin B chain (CRYAB) has been reported to stabilize mothers against decapentaplegic homolog 4 (SMAD4) in transforming growth factor‐β (TGF‐β) signaling, enabling target gene transcription. We show nuclear CRYAB–SMAD4 interaction for the first time in human skeletal muscle fibers and its regulation by exercise.
Kirill Schaaf, Cassandra Duda, Tihomir Kostov, Patrick Diel, Käthe Bersiner, Wilhelm Bloch, Sebastian Gehlert, Daniel Jacko   +7 more
wiley   +1 more source

ECM-Stiffness Mediated Persistent Fibroblast Activation Requires Integrin and Formin Dependent Chromatin Remodeling. [PDF]

Adv Sci (Weinh)
Packirisamy S, André O, Fan Z, Nordenfelt P, Swaminathan VS.   +4 more
europepmc   +1 more source

Citrullination and Deamidation in Type 1 Diabetes: Linking Beta Cell Stress to Neoantigen‐Driven Autoimmunity

Immunological Reviews, Volume 341, Issue 1, August 2026.
ABSTRACT Citrullination and deamidation are post‐translational modifications (PTMs) increasingly recognized as important contributors to neoepitope formation in type 1 diabetes (T1D). Under inflammatory and endoplasmic reticulum stress conditions, beta cells activate calcium‐dependent peptidylarginine deiminase and transglutaminase enzymes, leading to ...
Aïsha Callebaut, Ylke Bruggeman, Chantal Mathieu, Eddie A. James, Lut Overbergh   +4 more
wiley   +1 more source

Therapeutic Potential of Allomyrinasin in Oral Squamous Cell Carcinoma via Decreased NBC Activity. [PDF]

Pharmaceutics
Prismasari S, Kim HJ, Hong JH, Kang JY.
europepmc   +1 more source

EMF2 deficiency disrupts epigenetic and chromatin organization landscapes, blocking root regeneration competence in Arabidopsis

New Phytologist, Volume 251, Issue 4, Page 1792-1810, August 2026.
EMF2 mutation alters transcriptomic profiles in Arabidopsis calli while retaining responsiveness during root induction. Summary Plant de novo organogenesis depends on callus formation, yet the epigenetic mechanisms governing organ regeneration remain poorly understood.
Zhidan Wang, May Avraham, Tali Mandel, Leor Eshed Williams, Chang Liu   +4 more
wiley   +1 more source

A toxic STING-SAMHD1 axis drives replication stress in progeria and cancer cells. [PDF]

Nucleic Acids Res
Teodoro-Castro B, de Faria RC, Shashkova EV, Malique A, Adolph MB, Silva LND, Gonzalo S.   +6 more
europepmc   +1 more source

High-resolution nuclear cell biology by cryo-electron tomography. [PDF]

Nucleus
Kechagia Z, Medalia O.
europepmc   +1 more source

Lamins' role in osteosarcoma. [PDF]

Front Cell Dev Biol
Bagnato G, Peruzzi B.
europepmc   +1 more source

Baculoviruses exploit the mitotic kinase CDK1 to disrupt the nuclear lamina. [PDF]

PLoS Pathog
Mo M, Yu S, Yang Y, Liu J, Yang K, Yuan M.   +5 more
europepmc   +1 more source