Results 41 to 50 of about 96,178 (343)

Nuclear lamin phosphorylation: an emerging role in gene regulation and pathogenesis of laminopathies

The Nucleus, 2020
Decades of studies have established that nuclear lamin polymers form the nuclear lamina, a protein meshwork that supports the nuclear envelope structure and tethers heterochromatin to the nuclear periphery.
S. Liu, Kohta Ikegami
semanticscholar   +1 more source

Filament assembly of the C. elegans lamin in the absence of helix 1A

Nucleus, 2022
Lamins are the major constituent of the nuclear lamina, a protein meshwork underlying the inner nuclear membrane. Nuclear lamins are type V intermediate filaments that assemble into ~3.5 nm thick filaments.
Rebecca de Leeuw, Rafael Kronenberg-Tenga, Matthias Eibauer, Ohad Medalia   +3 more
doaj   +1 more source

Farnesyltransferase inhibitor treatment restores chromosome territory positions and active chromosome dynamics in Hutchinson-Gilford progeria syndrome cells [PDF]

, 2011
Copyright @ 2011 Mehta et al.; licensee BioMed Central Ltd. This article has been made available through the Brunel Open Access Publishing Fund. This is an open access article distributed under the terms of the Creative Commons Attribution License ...
Arican, HD, Bridger, JM, Eskiw, CH, Kill, IR, Mehta, IS   +4 more
core   +2 more sources

Reduced expression of lamin A/C correlates with poor histological differentiation and prognosis in primary gastric carcinoma

Journal of Experimental & Clinical Cancer Research, 2009
Background Lamin A/C is very important in DNA replication, RNA dependent transcription and nuclear stabilization. Reduced or absent lamin A/C expression has been found to be a common feature of a variety of different cancers.
Xu Dazhi, Weng Desheng, Wu Lirong, Wu Zhengrong, Geng Jian, Zhao Fei   +5 more
doaj   +1 more source

Lamin A, lamin B, and lamin B receptor analogues in yeast. [PDF]

The Journal of cell biology, 1989
Previous studies have shown that turkey erythrocyte lamin B is anchored to the nuclear envelope via a 58-kD integral membrane protein termed p58 or lamin B receptor (Worman H. J., J. Yuan, G. Blobel, and S. D. Georgatos. 1988. Proc. Natl. Acad. Sci. USA. 85:8531-8534). We now identify a p58 analogue in the yeast Saccharomyces cerevisiae.
Georgatos, S. D., Maroulakou, I., Blobel, G.   +2 more
openaire   +3 more sources

Pushing the (nuclear) envelope into meiosis. [PDF]

, 2013
A recent study shows that a short isoform of a mammalian nuclear lamin is important for homologous chromosome interactions during meiotic prophase in ...
Dernburg, Abby F
core   +1 more source

Surface Roughness Gradients Reveal Topography‐Specific Mechanosensitive Responses in Human Mesenchymal Stem Cells [PDF]

, 2020
The topographic features of an implant, which mechanically regulate cell behaviors and functions, are critical for the clinical success in tissue regeneration.
Camacho, Luis Cuellar, Haag, Rainer, Hou, Yong, Nie, Chuanxiong, Wei, Qiang, Xie, Wenyan, Yu, Leixiao, Zhang, Man   +7 more
core   +1 more source

Chromatin and lamin A determine two different mechanical response regimes of the cell nucleus

Molecular Biology of the Cell, 2017
Micromanipulation force measurements of single isolated nuclei at physiological strains and strain rates reveal two distinct cell nuclear mechanical regimes differentially governed by chromatin and lamin A.
Andrew D. Stephens, E. Banigan, S. Adam, R. Goldman, J. Marko   +4 more
semanticscholar   +1 more source

Theoretical Investigation of Structural, Electronic, and Optical Properties of ZnSnP2 Semiconductor

Annals of West University of Timisoara: Physics, 2022
The structural, electronic, and optical properties of ZnSnP2 compound were determined using the first principles calculations. We applied the full-potential enhanced plane wave method (FP-LAPW) within the framework of density functional theory (DFT) as ...
Ouledali M., Amrani B., Daoud S., Louhibi-Fasla S., Rekab-Djabri H., Beloufa N., Bekheira S., Ouadha I.   +7 more
doaj   +1 more source

Lamin A/C sustains PcG protein architecture, maintaining transcriptional repression at target genes [PDF]

, 2015
Beyond its role in providing structure to the nuclear envelope, lamin A/C is involved in transcriptional regulation. However, its cross talk with epigenetic factors--and how this cross talk influences physiological processes--is still unexplored.
Alessio Zippo, Alice Cortesi, Annagiusi Gargiulo, Asp, Ball, Bantignies, Bantignies, Beard, Beatrice Bodega, Bolte, Breiling, Caretti, Carpenter, Chiara Lanzuolo, Chiara Mozzetta, Cmarko, Cohen, Collas, Collins, Daniela Palacios, Delest, Dialynas, Elisa Cesarini, Fabrizia Marullo, Favreau, Francesco Gregoretti, Fredriksson, Frock, Gennaro Oliva, Gruenbaum, Gruenbaum, Harr, He, Hozák, Huang, Jahn, Juan, Kind, Kolb, Lanzuolo, Lanzuolo, Lanzuolo, Laura Antonelli, Lee, Lo Sardo, Lund, Marta Columbaro, Masny, Mattout, McCord, Melcon, Moir, Muñoz-Alarcón, Méjat, Oldenburg, Otsu, Palacios, Paro, Relaix, Riemer, Rosenblatt, Russ, Röber, Satijn, Scaffidi, Schiaffino, Schuettengruber, Schulze, Sezgin, Shimi, Shumaker, Simona Di Pelino, Solovei, Stefano Squarzoni, Stewart, Sullivan, Tolhuis, Trapnell, Wang, Wang, Woodhouse, Zaremba-Czogalla, Zwerger, Šmigová   +83 more
core   +1 more source