Results 11 to 20 of about 9,725,288 (229)
Both emerin and lamin C depend on lamin A for localization at the nuclear envelope [PDF]
, 2001 Physical interactions between lamins and emerin were investigated by co-immunoprecipitation of in vitro translated proteins. Emerin interacted with in vitro translated lamins A, B1 and C in co-immunprecipitation reactions.
Whitfield, WGF +8 more
core +8 more sources
Weaving a pattern from disparate threads: lamin function in nuclear assembly and DNA replication [PDF]
, 1994 The major residual structure that remains associated with the nuclear envelope following extraction of isolated nuclei or oocyte germinal vesicles with non-ionic detergents, nucleases and high salt is the lamina (Fawcett, 1966; Aaronson and Blobel ...
Hutchison, CJ +3 more
core +6 more sources
MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation. [PDF]
FEBS Open BioMARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Nakajima S +8 more
europepmc +2 more sources
Genome Biology, 2022 Background Interactions of chromatin with the nuclear lamina via lamina-associated domains (LADs) confer structural stability to the genome. The dynamics of positioning of LADs during differentiation, and how LADs impinge on developmental gene expression,
Julia Madsen-Østerbye +3 more
doaj +1 more source
Epigenetics & Chromatin, 2018 Background In animals with XY sex chromosomes, X-linked genes from a single X chromosome in males are imbalanced relative to autosomal genes. To minimize the impact of genic imbalance in male Drosophila, there is a dosage compensation complex (MSL) that ...
Hangnoh Lee, Brian Oliver
doaj +1 more source
Barrier-to-autointegration factor proteome reveals chromatin-regulatory partners. [PDF]
PLoS ONE, 2009 Nuclear lamin filaments and associated proteins form a nucleoskeletal ("lamina") network required for transcription, replication, chromatin organization and epigenetic regulation in metazoans.
Rocío Montes de Oca +4 more
doaj +1 more source
Optic nerve cavitations in glaucoma suspect and glaucoma patients
American Journal of Ophthalmology Case Reports, 2022 Purpose: Glaucoma is associated with structural changes of the optic nerve head such as deformation, lamina cribosa defects, prelaminar schisis, and peripapillary retinal schisis. We describe optic nerve cavitations that were detected by routine spectral
Bennett Y. Hong +5 more
doaj +1 more source
Role of histone deacetylases in gene regulation at nuclear lamina.
PLoS ONE, 2012 Theoretical models suggest that gene silencing at the nuclear periphery may involve "closing" of chromatin by transcriptional repressors, such as histone deacetylases (HDACs). Here we provide experimental evidence confirming these predictions.
Beatrice C Milon +7 more
doaj +1 more source
Involvement of the lamin rod domain in heterotypic lamin interactions important for nuclear organization [PDF]
, 2001 The nuclear lamina is a meshwork of intermediate-type filament proteins (lamins) that lines the inner nuclear membrane. The lamina is proposed to be an important determinant of nuclear structure, but there has been little direct testing of this idea.
Tinglu Guan +5 more
core +1 more source
Lack of evidence for sprouting of Aβ afferents into the superficial laminas of the spinal cord dorsal horn after nerve section [PDF]
, 2003 The central arborizations of large myelinated cutaneous afferents normally extend as far dorsally as the ventral part of lamina II in rat spinal cord. Woolf et al. (1992) reported that after nerve injury some of these afferents sprouted into lamina I and
Todd, A.J. +7 more
core +7 more sources