Results 111 to 120 of about 5,061 (213)
ESC Heart Failure, Volume 12, Issue 3, Page 2347-2352, June 2025.
Daigo Nishijo +19 more
wiley +1 more source
LMNA‐related muscular dystrophy presenting as an inflammatory myopathy
Annals of the Child Neurology SocietyIntroduction There are overlapping features between inflammatory myopathies and muscular dystrophies, particularly laminopathies. Key features that characterize laminopathies include axial and proximal weakness, contractures, and cardiac abnormalities ...
Alexandra Santana Almansa +7 more
doaj +1 more source
Nuclear damages and oxidative stress: new perspectives for laminopathies
European Journal of Histochemistry, 2012 Mutations in genes encoding nuclear envelope proteins, particularly LMNA encoding the A-type lamins, cause a broad range of diverse diseases, referred to as laminopathies.
G. Lattanzi +3 more
doaj +1 more source
Molecular Therapy: Nucleic AcidsHutchinson-Gilford progeria syndrome is a fatal genetic disorder caused by a point mutation in the gene encoding the nuclear envelope protein lamin A/C.
Volha Dzianisava +3 more
doaj +1 more source
From lamins to lamina: a structural perspective [PDF]
, 2018 Lamin proteins are the major constituents of the nuclear lamina, a proteinaceous network that lines the inner nuclear membrane. Primarily, the nuclear lamina provides structural support for the nucleus and the nuclear envelope; however, lamins and their ...
Medalia, Ohad, Zwerger, Monika
core
Recherche de l'expression de la lamine A et de la progérine chez des patients avec un syndrome myélodysplasique/syndrome myéloprolifératif avec thrombocytose [PDF]
, 2012 Les syndromes myélodysplasiques (SMD) et myéloprolifératifs (SMP) sont des maladies qui touchent les cellules souches de la moelle hématopoïétique.
Wuthrich, H.
core
Three-Dimensional Human iPSC-Derived Artificial Skeletal Muscles Model Muscular Dystrophies and Enable Multilineage Tissue Engineering [PDF]
, 2018 Generating human skeletal muscle models is instrumental for investigating muscle pathology and therapy. Here, we report the generation of three-dimensional (3D) artificial skeletal muscle tissue from human pluripotent stem cells, including induced ...
Cappellari, O +21 more
core
Potential therapeutic approaches for modulating expression and accumulation of defective lamin A in laminopathies and age-related diseases [PDF]
, 2012 core +1 more source
Chromatin states and nuclear organization in development — a view from the nuclear lamina [PDF]
, 2015 core +1 more source