Results 51 to 60 of about 18,858 (196)

Executive functions and self‐limited epilepsy with centro‐temporal spikes: A scoping review

open access: yesEpileptic Disorders, EarlyView.
Abstract Executive functions are a set of high‐level cognitive processes necessary for planning, organization, decision‐making, self‐control, and attention, and are carried out in the anterior frontal lobes. An impairment in executive functioning might present as difficulties in planning and organizing activities, in attention and concentration, in ...
Edoardo Fino   +6 more
wiley   +1 more source

L‐Relationship between uncertainty and average seizure frequency in clinical trials of antiseizure medications

open access: yesEpilepsia, EarlyView.
Abstract Objective Antiseizure medications are approved based on clinical trials that demonstrate their efficacy as measured by reductions in seizure frequency (SF). When designing these trials, trialists must select inclusion criteria where SF can be reliably measured to maintain statistical power.
Wesley T. Kerr   +6 more
wiley   +1 more source

Treatment Effects of Onion (Allium cepa) and Ginger

open access: yesBalkan Medical Journal, 2012
Objective: The aim of the present study was to evaluate the beneficial degree of sexual behavior in male rats after inducement of onion and ginger in lamotrigine receiving groups.
Hussein Nikniaz   +3 more
doaj  

Sex‐specific elevated incidence of glaucoma associated with topiramate versus valproate or lamotrigine in epilepsy, not migraine: A population‐based cohort study

open access: yesEpilepsia, EarlyView.
Abstract Objective Topiramate has been linked to increased glaucoma risk, potentially through mechanisms involving ocular fluid shifts. However, comparative risks vs other antiseizure medications (ASMs) and variation by sex or indication remain uncertain.
Cuiling Wei   +10 more
wiley   +1 more source

Mechanisms of SCN2A loss of function do not predict presence or phenotype of epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective SCN2A loss‐of‐function (LoF) variants are associated with epilepsy (onset age ≥ 3 months), intellectual disability (ID), and autism spectrum disorder (ASD). Despite numerous identified variants and the description of phenotypic subgroups, relationships between Nav1.2 channel dysfunction and clinical phenotypes remain unclear.
Marsha Tan   +23 more
wiley   +1 more source

Comparison of the Effects of Lamotrigine and Valproate on the Pentylenetetrazole-Induced Seizures and Behaviour of Immature Rats

open access: yesArchives of Epilepsy, 2018
Objectives:Epileptics, especially children, are more prone to behavioural deficits. Epilepsy related factors, psychosocial problems, treatment side effects may aggravate such deficits.
Mehmet Fatih GÖL   +3 more
doaj   +1 more source

Freedon study: Real‐life outcomes of cenobamate in different lines of treatment

open access: yesEpilepsia, EarlyView.
Abstract Objectives Cenobamate is an antiseizure medication (ASM) with proven effectiveness in individuals with highly refractory epilepsy. This study investigated the effectiveness and tolerability of cenobamate in different treatment lines and a less refractory setting. Methods This was a multicenter, retrospective, observational study.
Vicente Villanueva   +50 more
wiley   +1 more source

Reduced Frequency of Prolonged Sporadic Hemiplegic Migraine Attacks Following Fremanezumab Treatment-A Case Report. [PDF]

open access: yesEur J Neurol
A 64‐year‐old man was admitted to the stroke unit with acute aphasia and right‐sided hemiplegia, but imaging showed no signs of acute stroke. Symptoms gradually improved and fully resolved by Day 21, following the onset of a hemicranial headache. A diagnosis of sporadic hemiplegic migraine was made, and no further attacks occurred under fremanezumab ...
Hotz JF   +9 more
europepmc   +2 more sources

SV2A expression in blood cells as a possible biomarker candidate for levetiracetam treatment response

open access: yesEpilepsia, EarlyView.
Abstract Objective This study was undertaken to evaluate whether synaptic vesicle protein 2A (SV2A) expression on peripheral immune cells predicts treatment response to levetiracetam in epilepsy. Methods High‐dimensional flow cytometry was used to prospectively assess SV2A expression on immune cells from levetiracetam responders, nonresponders, and ...
Johannes Lang   +4 more
wiley   +1 more source

Insulin‐like growth factor 1 receptor correlates with verbal memory in ILAE type 2 hippocampal sclerosis

open access: yesEpilepsia, EarlyView.
Abstract Objective Long‐term memory deficits are often seen in patients with temporal lobe epilepsy (TLE). Recently, studies showed that patients with hippocampal sclerosis (HS) type 2, which presents with severe neuron loss in CA1 only, performed within the normal range. However, up to 30% of HS type 2 cases have memory deficits.
Henrique Cruz   +10 more
wiley   +1 more source

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