Results 1 to 10 of about 5,672 (207)
Langerin-expressing dendritic cells in pulmonary immune-related diseases [PDF]
Frontiers in Medicine, 2022 Dendritic cells (DCs) are “frontline” immune cells dedicated to antigen presentation. They serve as an important bridge connecting innate and adaptive immunity, and express various receptors for antigen capture.
Shurui Xuan +5 more
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Frontiers in Immunology, 2022 Cutaneous dendritic cells (DCs) have been implicated in the pathogenesis of atopic dermatitis (AD). However, the specific role of different subsets of DCs has not been well defined.
Chunying Xiao +10 more
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Glycosaminoglycans are interactants of Langerin: comparison with gp120 highlights an unexpected calcium-independent binding mode. [PDF]
PLoS ONE, 2012 Langerin is a C-type lectin specifically expressed in Langerhans cells. As recently shown for HIV, Langerin is thought to capture pathogens and mediate their internalisation into Birbeck Granules for elimination.
Eric Chabrol +7 more
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Birbeck granule-like "organized smooth endoplasmic reticulum" resulting from the expression of a cytoplasmic YFP-tagged langerin. [PDF]
PLoS ONE, 2013 Langerin is required for the biogenesis of Birbeck granules (BGs), the characteristic organelles of Langerhans cells. We previously used a Langerin-YFP fusion protein having a C-terminal luminal YFP tag to dynamically decipher the molecular and cellular ...
Cédric Lenormand +14 more
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Targeting of the C-Type Lectin Receptor Langerin Using Bifunctional Mannosylated Antigens
Frontiers in Cell and Developmental Biology, 2020 Langerhans cells (LCs) are antigen-presenting cells that reside in the skin. They uniquely express high levels of the C-type lectin receptor Langerin (CD207), which is an attractive target for antigen delivery in immunotherapeutic vaccination strategies ...
Rui-Jun Eveline Li +12 more
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Peritumoural and Intratumoural Distribution of Langerhan Cell in Oral Squamous Cell Carcinoma and its Association with Known Prognostic Factors [PDF]
Journal of Clinical and Diagnostic Research, 2023 Introduction: Oral Squamous Cell Carcinoma (OSCC) accounts for about 2/3rd of the Head and Neck Squamous Cell Carcinomas (HNSCC). It is the sixth most common cancer worldwide and the third most common cancer in developing countries including India.
Sandhra Papparath Usman +2 more
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Indeterminate dendritic cell tumor (IDCT) [PDF]
Vestnik Dermatologii i Venerologii, 2023 Indeterminate dendritic cell tumor (IDCT) is rare histiocytic tumor characterized by the proliferation of indeterminate dendritic cells. It is more often diagnosed in middle-aged people, in approximately equal proportions in men and women.
Evgenia V. Okladnikova +4 more
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eLife, 2022 Langerhans cells are specialized antigen-presenting cells localized within the epidermis and mucosal epithelium. Upon contact with Langerhans cells, pathogens are captured by the C-type lectin langerin and internalized into a structurally unique vesicle ...
Toshiyuki Oda +4 more
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CD11b+ migratory dendritic cells mediate CD8 T cell cross-priming and cutaneous imprinting after topical immunization. [PDF]
PLoS ONE, 2014 Topical antigen application is a focus of current vaccine research. This immunization route mimics natural antigen exposure across a barrier tissue and generates T cells imprinted for skin-selective homing.
Suzanne T Nizza, James J Campbell
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Journal of Innate Immunity, 2022 Contrasting the antigen-presenting dendritic cells (DCs) in the conducting airways, the alveolar DC populations in human lungs have remained poorly investigated. Consequently, little is known about how alveolar DCs are altered in diseases such as chronic
Michiko Mori +10 more
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