Results 91 to 100 of about 8,574 (229)

Calcitonin gene-related peptide inhibits Langerhans cell-mediated HIV-1 transmission. [PDF]

, 2013
International audienceUpon its mucosal entry, human immunodeficiency virus type 1 (HIV-1) is internalized by Langerhans cells (LCs) in stratified epithelia and transferred locally to T cells.
Ahmed, Anne-Sophie Drillet-Dangeard, Asahina, Bailey, Blanco-Melo, Bomsel, Brain, Daniela Tudor, de Witte, Ding, Ding, Ganor, Ganor, Ganor, Geijtenbeek, Geissmann, Giuseppe Tambussi, Griffiths, Hosoi, Lucia Lopalco, Magérus-Chatinet, Marc Zerbib, Masterson, Mc Dermott, McCarthy, Moreno, Morgane Bomsel, Nicolas Barry Delongchamps, Olesen, Poyner, Rosenfeld, Sams, Schifter, Torii, Walker, Yonatan Ganor, Zhou, Zhou   +37 more
core   +4 more sources

Sotatercept in Pulmonary Langerhans Cell Histiocytosis‐Associated Pulmonary Hypertension: A Case Series and Systematic Review

Pulmonary Circulation, Volume 16, Issue 1, January 2026.
ABSTRACT Pulmonary Langerhans cell histiocytosis (PLCH) frequently complicated by pulmonary hypertension (PH), which markedly worsens prognosis. We retrospectively reviewed three institutional PLCH‐PH cases treated with off‐label Sotatercept added to background triple therapy and performed a systematic review of published PLCH‐PH reports (PubMed/Embase
Giorgi Chilingarashvili, Ruben Joseph Mylvaganam, Roberto J. Bernardo, Aimal Shah, Michael Cuttica, Tara Roberts, Nathaniel Marchetti, Parth Rali   +7 more
wiley   +1 more source

Bacterial Polysaccharide Specificity of the Pattern Recognition Receptor Langerin Is Highly Species-dependent [PDF]

Journal of Biological Chemistry, 2017
JBC papers in press 292(3), 862 - 871 (2017).
Hanske, J., Schulze, J., Aretz, J., McBride, R., Loll, B., Schmidt, H., Knirel, Y., Rabsch, W., Wahl, M., Paulson, J., Rademacher, C.   +10 more
openaire   +4 more sources

Ezh2 Controls Skin Tolerance through Distinct Mechanisms in Different Subsets of Skin Dendritic Cells

iScience, 2018
Summary: Ezh2, a well-established epigenetic repressor, can down-regulate leukocyte inflammatory responses, but its role in cutaneous health remains elusive.
Jia Tong Loh, Thomas Jun Feng Lim, Kyoko Ikumi, Takuma Matoba, Baptiste Janela, Merry Gunawan, Tatsuya Toyama, Maegan Bunjamin, Lai Guan Ng, Michael Poidinger, Akimichi Morita, Florent Ginhoux, Sayuri Yamazaki, Kong-Peng Lam, I-hsin Su   +14 more
doaj   +1 more source

What contributes to an effective mannose recognition domain? [PDF]

, 2017
In general, carbohydrate-lectin interactions are characterized by high specificity but also low affinity. The main reason for the low affinities are desolvation costs, due to the numerous hydroxy groups present on the ligand, together with the typically ...
Eriş, Deniz, Ernst, Beat, Hevey, Rachel, Sager, Christoph P., Smieško, Martin   +4 more
core   +3 more sources

Dendritic cells and the extracellular matrix : A challenge for maintaining tolerance/homeostasis [PDF]

, 2015
Supported by The Royal College of Surgeons of Edinburgh. ACKNOWLEDGMENTS We would like to thank the Microscopy Core Facility and the Medical Research Facility at the University of Aberdeen for technical assistance.
Forrester, John, Kuffova, Lucia, Shankar, Sucharita Panuganti   +2 more
core   +1 more source

Involvement of langerin in the protective function of a keratan sulfate-based disaccharide in an emphysema mouse model [PDF]

, 2023
Yuki Ohkawa, Noriko Kanto, Miyako Nakano, Reiko Fujinawa, Yasuhiko Kizuka, Emma Lee Johnson, Yoichiro Harada, Jun‐ichi Tamura, Naoyuki Taniguchi   +8 more
openalex   +1 more source

Langerin-expressing and CD83-expressing cells in oral lichen planus lesions

Acta Odontologica Scandinavica, 2007
Dendritic Langerhans cells (LCs) have been attributed a role in the pathogenesis of lichen planus as autoantigen-presenting cells initiating expansion of autoreactive T cells. Langerin and CD83, which are cell molecules expressed on LCs, are associated with antigen presentation.
Jenny R. Gustafson, Christina Eklund, Mats Wallström, Göran Zellin, Bengt Magnusson, Bengt Hasséus   +5 more
openalex   +3 more sources

Expression of Langerin/CD207 reveals dendritic cell heterogeneity between inbred mouse strains [PDF]

Immunology, 2008
SummaryLangerin/CD207 is expressed by a subset of dendritic cells (DC), the epithelial Langerhans cells. However, langerin is also detected among lymphoid tissue DC. Here, we describe striking differences in langerin‐expressing cells between inbred mouse strains. While langerin+ cells are observed in comparable numbers and with comparable phenotypes in
Flacher, Vincent, Douillard, Patrice, Aït-Yahia, Smina, Stoitzner, Patrizia, Clair-Moninot, Valérie, Romani, Nikolaus, Saeland, Sem   +6 more
openaire   +3 more sources

Polysaccharide Adjuvants as Innate Immune Trainers: Bridging Pattern Recognition Receptor (PRR) Activation and Metabolic Reprogramming for Synthetic Vaccine Design

Advanced Science, Volume 12, Issue 48, December 29, 2025.
Polysaccharides modulate immune responses by engaging pattern recognition receptors (PRRs) to induce T‐cell activation. In vaccine design, their particle size critically influences lymph node targeting and activation mechanisms. By engineering structural complexity and multivalent PRR engagement, polysaccharides enable precise modulation of immune ...
Jeong Hyun Moon, May Thazin Phoo, Yubin Kim, Jinsung Ahn, April Kim, Jutaek Nam, Soo‐Hong Lee, James J. Moon, Sejin Son   +8 more
wiley   +1 more source