Results 41 to 50 of about 8,574 (229)

Host Langerin (CD207) is a receptor for Yersinia pestis phagocytosis and promotes dissemination [PDF]

, 2015
Yersinia pestis is a Gram-negative bacterium that causes plague. After Y. pestis overcomes the skin barrier, it encounters antigen-presenting cells (APCs), such as Langerhans and dendritic cells.
Anyi Li, Chae G Park, Cheolho Cheong, Gottfried RS., Gregory V Plano, Honghui Ding, Hongping Huang, John D Klena, Kun Yang, Lianxu Xia, Lin Zhang, Lingyu Jiang, Mikael Skurnik, Pei Zhang, Sara S Bartra, Shaogang Wang, Shusheng Zhang, Silvia Bulgheresi, Tie Chen, Yingxia He, Yiping Wu   +20 more
core   +1 more source

Effect of ultrasound treatment of the skin on activation of Langerhans cells and antibody production in rodents

Journal of Advanced Pharmaceutical Technology & Research, 2023
In this study, we investigated whether stimulating the skin with ultrasound (US) could activate Langerhans cells (LCs) – antigen-presenting cells in the epidermis and stimulate antibody production following the subcutaneous and intradermal injection of ...
Satoko Enjo, Yutaro Hazama, Soichiro Kimura, Yasunori Morimoto, Hideo Ueda   +4 more
doaj   +1 more source

Flt3L-dependence helps define an uncharacterized subset of murine cutaneous dendritic cells [PDF]

, 2014
Skin-derived dendritic cells (DC) are potent antigen presenting cells with critical roles in both adaptive immunity and tolerance to self. Skin DC carry antigens and constitutively migrate to the skin draining lymph nodes (LN).
Anandasabapathy, Niroshana, Cheong, Cheolho, Dobrin, Joseph, Feder, Rachel, Matos, Ines, Mollah, Shamim, Steinman, Ralph M., Tse, Sze-Wah   +7 more
core   +1 more source

HIV Types, Groups, Subtypes and Recombinant Forms: Errors in Replication, Selection Pressure and Quasispecies [PDF]

, 2012
HIV-1 is a chimpanzee virus which was transmitted to humans by several zoonotic events resulting in infection with HIV-1 groups M P, and in parallel transmission events from sooty mangabey monkey viruses leading to infections with HIV-2 groups A H.
Alvarez M, Batmanian J, Bocharov G, Brennan CA, Burgard M, Buzon MJ, Dahl V, Dai L, Domingo E, Duarte EA, Etienne L, Fang G, Fultz PN, Gunthard HF, Henriet S, Iordanskiy S, Josef Eberle, Julg B, Kijak GH, Korber B, Law M, Lemey P, Lorenzo-Redondo R, Lutz G. Gürtler, Motomura K, Neel C, Onafuwa-Nuga A, Pathak VK, Pathak VK, Rachinger A, Sauter D, Shimizu N, Simon-Loriere E, Smith DM, Sterjovski J, Swenson LC, Tienen C, Troyer JL, Van der Kuyl AC, Van der Vlist M, Zhu T   +40 more
core   +1 more source

CD1a and langerin: acting as more than Langerhans cell markers [PDF]

Journal of Clinical Investigation, 2004
Langerhans cells (LCs) represent a unique DC subset populating the outermost body surface, i.e., the epidermis. Although CD1a and langerin (CD207) are used as specific markers to distinguish LCs from other DC subsets, their immunological functions have remained mostly unknown.
Norikatsu, Mizumoto, Akira, Takashima
openaire   +2 more sources

Genetic characterisation of Langerin gene in human immunodeficiency virus-1-infected women from Bahia, Brazil

Memorias do Instituto Oswaldo Cruz, 2014
Studies on human genetic variations are a useful source of knowledge about human immunodeficiency virus (HIV)-1 infection. The Langerin protein, found at the surface of Langerhans cells, has an important protective role in HIV-1 infection. Differences in
Giselle Calasans de Souza Costa, Jaqueline Goes Jesus, Filipe Ferreira de Almeida Rego, Edson Souza Santos, Bernardo Galvão-Castro, Marilda de Souza Gonçalves, Luiz Carlos Júnior Alcantara   +6 more
doaj   +1 more source

Syndecan 4 Upregulation on Activated Langerhans Cells Counteracts Langerin Restriction to Facilitate Hepatitis C Virus Transmission

Frontiers in Immunology, 2020
Sexually transmitted Hepatitis C virus (HCV) infections and high reinfections are a major concern amongst men who have sex with men (MSM) living with HIV-1 and HIV-negative MSM.
Bernadien M. Nijmeijer, Julia Eder, Catharina J. M. Langedijk, Tanja M. Kaptein, Sofie Meeussen, Pascale Zimmermann, Pascale Zimmermann, Carla M. S. Ribeiro, Teunis B. H. Geijtenbeek   +8 more
doaj   +1 more source

Identification and expression of mouse Langerin (CD207) in dendritic cells [PDF]

International Immunology, 2002
We have cloned the mouse homologue of human Langerin (h-Langerin), a type II transmembrane protein with a single external C-type lectin domain. Mouse Langerin (m-Langerin) displays 65 and 74% homologies in total amino acid and lectin domains with those of h-Langerin. The cognate mouse and rat genes were assigned to chromosome 6D1-D2 and chromosome 4q33
Takahara, Kazuhiko, Omatsu, Yoshiki, Yashima, Yusuke, Maeda, Yasuhiro, Tanaka, Shusaku, Iyoda, Tomonori, Clausen, Björn E., Matsubara, Kazumi, Letterio, John, Steinman, Ralph M., Matsuda, Yoichi, Inaba, Kayo, Clusen, Bjöern   +12 more
openaire   +3 more sources

Langerin+ CD8α+ Dendritic Cells Drive Early CD8+ T Cell Activation and IL-12 Production During Systemic Bacterial Infection

Frontiers in Immunology, 2018
Bloodstream infections induce considerable morbidity, high mortality, and represent a significant burden of cost in health care; however, our understanding of the immune response to bacteremia is incomplete.
Kelly A. Prendergast, Kelly A. Prendergast, Naomi J. Daniels, Troels R. Petersen, Ian F. Hermans, Ian F. Hermans, Ian F. Hermans, Joanna R. Kirman, Joanna R. Kirman   +8 more
doaj   +1 more source

Langerin Expressing Cells Promote Skin Immune Responses under Defined Conditions [PDF]

The Journal of Immunology, 2008
Abstract There are conflicting data in the literature regarding the role of epidermal Langerhans cells (LC) in promoting skin immune responses. On one hand, LC can be extremely potent APCs in vitro, and are thought to be involved in contact hypersensitivity (CHS).
Wang, Liangchun, Bursch, Laura S, Kissenpfennig, Adrien, Malissen, Bernard, Jameson, Stephen C, Hogquist, Kristin A   +5 more
openaire   +3 more sources