Hypomorphic mutation in the RAG2 gene affects dendritic cell distribution and migration. [PDF]
, 2013 In Omenn syndrome, altered dendritic cell distribution and impaired migration represent an additional level of immune dysregulation, contributing to the pathogenesis of autoimmunity. OS is a severe combined immunodeficiency characterized by erythrodermia
Anselmo A +10 more
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A population of Langerin-positive dendritic cells in murine Peyer's patches involved in sampling β-glucan microparticles. [PDF]
PLoS ONE, 2014 Glucan particles (GPs) are 2-4 μm hollow, porous shells composed of 1,3-β-D-glucan that have been effectively used for oral targeted-delivery of a wide range of payloads, including small molecules, siRNA, DNA, and protein antigens.
Magdia De Jesus +4 more
doaj +1 more source
Peripheral CD103+ dendritic cells form a unified subset developmentally related to CD8α+ conventional dendritic cells [PDF]
, 2010 Although CD103-expressing dendritic cells (DCs) are widely present in nonlymphoid tissues, the transcription factors controlling their development and their relationship to other DC subsets remain unclear. Mice lacking the transcription factor Batf3 have
Aliberti +75 more
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Dendritic Cell Migration: An Essential Step in Initiating Adaptive Immunity Across Tissues. [PDF]
Immunol RevABSTRACT Immune surveillance of tissues is primarily carried out by dendritic cells (DCs), which act as sentinels for the adaptive immune system. To accomplish this task, DCs migrate from tissues to regional lymph nodes, or from blood‐exposed regions of the spleen to the white pulp, to prime T cell responses. DC migration is a tightly regulated process
Olson EC, Williams A, Eisenbarth SC.
europepmc +2 more sources
Increase of DC-LAMP+ mature dendritic cell subsets in dermatopathic lymphadenitis of mycosis fungoides [PDF]
, 2014 Background: Little is known about the immunological milieu of the skin-draining lymph nodes (LNs) in mycosis fungoides (MF). Objectives: We studied dendritic cell (DC) subsets in the dermatopathic lymphadenitis of MF patients.
Aoyama, Yumi +8 more
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Batf3-dependent CD11b(low/-) peripheral dendritic cells are GM-CSF-independent and are not required for Th cell priming after subcutaneous immunization. [PDF]
PLoS ONE, 2011 Dendritic cells (DCs) subsets differ in precursor cell of origin, functional properties, requirements for growth factors, and dependence on transcription factors.
Brian T Edelson +9 more
doaj +1 more source
, 2012 After activation, Langerhans cells (LC), a distinct subpopulation of epidermis-resident dendritic cells, migrate from skin to lymph nodes where they regulate the magnitude and quality of immune responses initiated by epicutaneously applied antigens ...
Feng, X. +7 more
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HIV target cells and innate immune factors in the human female genital tract [PDF]
, 2011 World-wide, human immunodeficiency virus (HIV) transmission most often takes place in the genital tract during heterosexual intercourse, but the site where HIV most commonly establishes primary infection in the female genital tract remains unknown ...
Kaldensjö, Tove
core +1 more source
Hepatic Langerhans cell histiocytosis: Report of a rare case
Human Pathology Reports, 2023 Langerhans cell histiocytosis (LCH) is a rare neoplastic disease characterized by abnormal proliferation of Langerhans cells infiltrating various organs, resulting in organ dysfunction.
Renling Yao, Jun Chen, Jie Li
doaj +1 more source
Frontiers in Immunology, 2018 Peri-implantitis is a destructive inflammatory process affecting tissues surrounding dental implants and it is considered a new global health concern.
Oded Heyman +10 more
doaj +1 more source