Results 61 to 70 of about 8,574 (229)
The Essential Role of anxA2 in Langerhans Cell Birbeck Granules Formation
Cells, 2020 Langerhans cells (LC) are the resident antigen presenting cells of the mucosal epithelium and play an essential role in initiating immune responses.
Shantae M. Thornton +7 more
doaj +1 more source
Activin A induces Langerhans cell differentiation in vitro and in human skin explants. [PDF]
PLoS ONE, 2008 Langerhans cells (LC) represent a well characterized subset of dendritic cells located in the epidermis of skin and mucosae. In vivo, they originate from resident and blood-borne precursors in the presence of keratinocyte-derived TGFbeta.
Tiziana Musso +14 more
doaj +1 more source
Studies of human dendritic cells in the skin after antigen exposure [PDF]
, 2012 Dendritic cells (DCs) act at the interface of innate and adaptive immunity. They are capable of inducing strong effector immune responses to invading pathogens, but also exert important functions in the maintenance of tolerance.
Bond, Emily
core +1 more source
Identification and Characterization of Endogenous Langerin Ligands in Murine Extracellular Matrix [PDF]
Journal of Investigative Dermatology, 2006 Langerin is a C-type lectin that is expressed by Langerhans cells (LC) and related immune cells, and believed to play an important role in antigen recognition and uptake. To determine if Langerin has endogenous ligands, we generated S protein binding, bacterial recombinant, mouse soluble Langerin, and utilized it as a probe.
Tada, Yayoi +6 more
openaire +2 more sources
Animal Research and One Health, EarlyView.The AMP‐induced mutant Staphylococcus aureus strain nzR showed increased resistance, five gene mutations, and decreased surface anion levels. AMPs affect the NDH‐2 protein encoded by ndh gene inhibiting the growth of S. aureus. The deletion of the ndh gene promotes the development of AMPs resistance.
Lingyu Xiao +12 more
wiley +1 more source
Characterization of Langerin-Expressing Dendritic Cell Subsets in the Normal Cornea [PDF]
Investigative Opthalmology & Visual Science, 2011 In addition to Langerhans cells (LCs), other dendritic cells (CD11c(+)) have recently been shown to express Langerin (c-type lectin). In skin, (non-LC) Langerin+ dendritic cells initiate adaptive immunity. However, whether such dendritic cells (DC) reside in the cornea, an immune-privileged tissue, is unknown.Normal C57BL/6 corneas were harvested for ...
Hattori, Takaaki +6 more
openaire +3 more sources
Folia Histochemica et Cytobiologica, 2007 Langerhans cell histiocytoses (LCH) represent rare diseases of unclear etiology and pathogenesis. Most of the cases include children, 1 to 15 years of age, and various organs are involved (bones, skin, liver, lymph nodes, bone marrow and other).
Marzena Podhorska-Okołów +8 more
doaj +1 more source
An unusual case of intertrigo in an adult caused by purely cutaneous Langerhans cell histiocytosis [PDF]
, 2016 We report a case of persistent intertrigo in an adult, eventually diagnosed as cutaneous Langerhans cell histiocytosis (LCH). It is known that LCH has a predilection for intertriginous areas, however purely cutaneous disease as in our case, is uncommon ...
Baldacchino, Godfrey +3 more
core
Targeting antigens to dendritic cell receptors for vaccine development [PDF]
, 2013 Dendritic cells (DCs) are highly specialized antigen presenting cells of the immune system which play a key role in regulating immune responses. Depending on the method of antigen delivery, DCs stimulate immune responses or induce tolerance.
Apostolopoulos, Vasso +3 more
core +2 more sources
Nanogel‐Mediated Immunotherapy to Tackle Cancer and Inflammatory Diseases
ChemistryEurope, EarlyView.Nanogels formed through self‐assembly, microemulsion, or precipitation polymerization method enable precise delivery of immunotherapeutic factors and immune cell targeting, thus effectively modulating immune responses. This review highlights recent advances in stimuli‐responsive nanogel design, underlying mechanisms, and their potentials to tackle ...
Ziwen Zhang +7 more
wiley +1 more source