HIV target cells and innate immune factors in the human female genital tract [PDF]
World-wide, human immunodeficiency virus (HIV) transmission most often takes place in the genital tract during heterosexual intercourse, but the site where HIV most commonly establishes primary infection in the female genital tract remains unknown ...
Kaldensjö, Tove
core +1 more source
Batf3-dependent CD11b(low/-) peripheral dendritic cells are GM-CSF-independent and are not required for Th cell priming after subcutaneous immunization. [PDF]
Dendritic cells (DCs) subsets differ in precursor cell of origin, functional properties, requirements for growth factors, and dependence on transcription factors.
Brian T Edelson +9 more
doaj +1 more source
After activation, Langerhans cells (LC), a distinct subpopulation of epidermis-resident dendritic cells, migrate from skin to lymph nodes where they regulate the magnitude and quality of immune responses initiated by epicutaneously applied antigens ...
Feng, X. +7 more
core +1 more source
Hepatic Langerhans cell histiocytosis: Report of a rare case
Langerhans cell histiocytosis (LCH) is a rare neoplastic disease characterized by abnormal proliferation of Langerhans cells infiltrating various organs, resulting in organ dysfunction.
Renling Yao, Jun Chen, Jie Li
doaj +1 more source
Langerin, the “Catcher in the Rye”: An important receptor for pathogens on Langerhans cells [PDF]
AbstractLangerhans cells (LCs) are a distinct subset of DCs that resides in the epidermis and other epithelia. They are potent antigen‐presenting cells and strong inducers of T‐cell responses. Like other DC types, LCs express C‐type lectins that serve as antigen/pathogen uptake receptors, with Langerin/CD207 being the characteristic LC C‐type lectin ...
Nikolaus Romani, Patrizia Stoitzner
openaire +3 more sources
Peri-implantitis is a destructive inflammatory process affecting tissues surrounding dental implants and it is considered a new global health concern.
Oded Heyman +10 more
doaj +1 more source
Activin A induces Langerhans cell differentiation in vitro and in human skin explants. [PDF]
Langerhans cells (LC) represent a well characterized subset of dendritic cells located in the epidermis of skin and mucosae. In vivo, they originate from resident and blood-borne precursors in the presence of keratinocyte-derived TGFbeta.
Tiziana Musso +14 more
doaj +1 more source
Identification and Characterization of an Alternatively Spliced Isoform of Mouse Langerin/CD207 [PDF]
The mouse homologue of human Langerin (CD207), a novel Langerhans cells (LC)-restricted C-type lectin that likely participates in antigen recognition and uptake, has been recently identified. In this study, we isolated the mouse Langerin cDNA from murine fetal skin-derived dendritic cells (FSDDC) by subtractive cloning and rapid amplification of cDNA ...
Yayoi Tada +2 more
openaire +3 more sources
Targeting antigens to dendritic cell receptors for vaccine development [PDF]
Dendritic cells (DCs) are highly specialized antigen presenting cells of the immune system which play a key role in regulating immune responses. Depending on the method of antigen delivery, DCs stimulate immune responses or induce tolerance.
Apostolopoulos, Vasso +3 more
core +2 more sources
Characterization of Langerin-Expressing Dendritic Cell Subsets in the Normal Cornea [PDF]
In addition to Langerhans cells (LCs), other dendritic cells (CD11c(+)) have recently been shown to express Langerin (c-type lectin). In skin, (non-LC) Langerin+ dendritic cells initiate adaptive immunity. However, whether such dendritic cells (DC) reside in the cornea, an immune-privileged tissue, is unknown.Normal C57BL/6 corneas were harvested for ...
Daniel H. Kaplan +11 more
openaire +4 more sources

