Phenotype, Squalene, and Lanosterol Content Variation Patterns During Seed Maturation in Different Leaf-Color Tea Cultivars [PDF]
FoodsSqualene and lanosterol are bioactive compounds with diverse physiological effects, found in relatively high concentrations in tea seed oil. Their levels are significantly influenced by cultivar and fruit maturity.
Jing-Jing Ye +8 more
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A Comparative Study of the Effects of Cholesterol and Lanosterol on Hydrated Phosphatidylethanolamine Assemblies: Focusing on Physical Parameters Related to Membrane Fusion [PDF]
MembranesCholesterol (Chol) plays a crucial role in regulating membrane properties and biological processes such as membrane fusion, yet the molecular mechanisms underlying its function remain incompletely understood.
Ayumi Okayama +2 more
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Biosynthesis of lanosterol in Escherichia coli [PDF]
Synthetic and Systems BiotechnologyLipid composition represents a significant differentiator across the three domains (eukaryotes, bacteria, and archaea) of cellular life. Eukaryotes possess distinct lipids, such as sterols and sphingolipids, generally, these are not commonly found in ...
Wenjie Sun +4 more
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Ocular delivery of lipid nanoparticles-formulated mRNA encoding lanosterol synthase ameliorates cataract in rats [PDF]
Nature CommunicationsCataract caused by crystallin aggregation is the leading cause of vision impairment and blindness globally. The only available treatment option so far is surgery.
Ruiteng Song +6 more
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Post-lanosterol inhibition profile based classification of commonly used prescription medications [PDF]
Translational PsychiatryCholesterol is an essential structural component of all cells, and the sterol biosynthetic pathway provides critical precursors for essential homeostatic molecules. Sterol biosynthesis can be disrupted by pathogenic variants in genes, as well as commonly
Keri A. Tallman +4 more
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Effect of lanosterol on human cataract nucleus
Indian Journal of Ophthalmology, 2015 Aim: To study the effect of lanosterol on age-related cataractous human lens nuclei. Materials and Methods: Forty age-related cataractous nuclei removed during manual small incision cataract surgery were obtained and randomly immersed in 25 mM lanosterol
P Mahesh Shanmugam +6 more
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The Oxidosqualene Cyclase from the Oomycete Saprolegnia Parasitica Synthesizes Lanosterol as a Single Product [PDF]
Frontiers in Microbiology, 2016 The first committed step of sterol biosynthesis is the cyclisation of 2,3-oxidosqualene to form either lanosterol or cycloartenol. This is catalyzed by an oxidosqualene cyclase.
Paul Dahlin +5 more
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Journal of Dairy Science, 2023 : Milk contains several components that are important for human nutrition and health. To date, studies on organic and conventional milk have focused on their gross composition and fatty acid content, but little attention has been paid to the differences ...
M. Martini +4 more
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Pharmaceutics, 2022 It has recently been reported that lanosterol (LAN) plays a preventive role against lens opacification through the reversal of crystalline aggregation. However, the effect of LAN is not sufficient to restore lens transparency.
Saori Deguchi +8 more
doaj +1 more source
Efficient routes to epimerically-pure side-chain derivatives of lanosterol [PDF]
, 2004 A technically simple route is described to individual epimers of side-chain derivatives of lanosterol (3-hydroxy-5-lanosta-8,24-diene). Epimerically pure 24,25-epoxy-, 24,25-dihydroxy- and 24-bromo-25-hydroxy-lanosterol have been prepared in good yield ...
Kavtaradze, Levan K. +2 more
core +4 more sources