Results 41 to 50 of about 6,528 (248)

Genome-Guided Mass Spectrometry Expedited the Discovery of Paraplantaricin TC318, a Lantibiotic Produced by Lactobacillus paraplantarum Strain Isolated From Cheese

open access: yesFrontiers in Microbiology, 2020
The quest for potent alternatives to the currently used antimicrobials is urged by health professionals, considering the rapid rise in resistance to preservatives and antibiotics among pathogens.
Walaa E. Hussein   +8 more
doaj   +1 more source

Isolation and Analysis of the Nisin Biosynthesis Complex NisBTC: further Insights into Their Cooperative Action

open access: yesmBio, 2021
Lantibiotics are ribosomally synthesized and posttranslationally modified peptide antibiotics. Although the membrane-associated lantibiotic biosynthesis machinery has long been proposed to exist, the isolation of such a complex has not been reported yet,
Jingqi Chen, Oscar P. Kuipers
doaj   +1 more source

Identification of the amino acid labionin and its desulfurised derivative in the type-III lantibiotic LabA2 by means of GC/MS [PDF]

open access: yes, 2011
Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG geförderten) Allianz- bzw. Nationallizenz frei zugänglich.This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence
Henkel, Maik   +2 more
core   +1 more source

Non-Proteinogenic Amino Acids in Lacticin 481 Analogues Result in More Potent Inhibition of Peptidoglycan Transglycosylation [PDF]

open access: yes, 2012
Lantibiotics are ribosomally synthesized and post-translationally modified peptide natural products that contain the thioether structures lanthionine and methyllanthionine and exert potent antimicrobial activity against Gram-positive bacteria. At present,
Garcia De Gonzalo, Chantal V.   +5 more
core   +1 more source

Potential value of bacteriocins in the etiological treatment of infectious diseases of the respiratory tract

open access: yesZdorovʹe Rebenka, 2017
Bacteriocins are ribosomal-synthesized hydrophobic antimicrobial peptides with a broad antimicrobial spectrum of action. Gram-positive bacteria are the main source of bacteriocins.
А.Е. Abaturov, Т.А. Kryuchko
doaj   +1 more source

Phylogeny-guided genome mining of roseocin family lantibiotics to generate improved variants of roseocin

open access: yesAMB Express, 2023
Keypoints Taxonomically distant species have a wide diversity of roseocin family lantibiotics. The phylogeny-guided approach opens new possibilities for RiPPs bioengineering.
Sandeep Chaudhary   +6 more
doaj   +1 more source

Substrate control in stereoselective lanthionine biosynthesis. [PDF]

open access: yes, 2015
Enzymes are typically highly stereoselective catalysts that enforce a reactive conformation on their native substrates. We report here a rare example in which the substrate controls the stereoselectivity of an enzyme-catalysed Michael-type addition ...
Houk, KN   +3 more
core   +2 more sources

Protein defence systems against the lantibiotic nisin: Function of the immunity protein NisI and the resistance protein NSR

open access: yesFrontiers in Microbiology, 2016
Lantibiotics are potential alternatives to antibiotics because of their broad-range killing spectrum. The producer strain is immune against its own synthesized lantibiotic via the expression of two proteins LanI and LanFEG.
Sakshi eKhosa   +2 more
doaj   +1 more source

Structure of the Response Regulator NsrR from Streptococcus agalactiae, Which Is Involved in Lantibiotic Resistance. [PDF]

open access: yesPLoS ONE, 2016
Lantibiotics are antimicrobial peptides produced by Gram-positive bacteria. Interestingly, several clinically relevant and human pathogenic strains are inherently resistant towards lantibiotics.
Sakshi Khosa   +4 more
doaj   +1 more source

Genome comparison and physiological characterization of eight Streptococcus thermophilus strains isolated from Italian dairy products [PDF]

open access: yes, 2017
Eight Streptococcus thermophilus strains of dairy origin isolated in Italy were chosen to investigate autochthonous bacterial diversity in this important technological species. In the present study a comparative analysis of all the 17 S.
Campanaro, Stefano   +5 more
core   +1 more source

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