Results 161 to 170 of about 307,788 (176)
Biomedical Chromatography, Volume 40, Issue 10, October 2026.ABSTRACT RU 58841 is a nonsteroidal antiandrogen, developed for the treatment of androgen‐dependent conditions. This study aimed to characterize the human metabolism of RU 58841 for the first time and to assess its systemic exposure following topical administration.
Aylin Okutan +4 more
wiley +1 more source
Journal of Mass Spectrometry, Volume 61, Issue 10, October 2026.ABSTRACT Based on previous experience and current knowledge, it is assumed that mycotoxins contaminating raw materials could be degraded or modified due to exposure to thermal and mechanical conditions during food processing, potentially resulting in degradation and/or conversion products.
Eleonora Rollo +5 more
wiley +1 more source
Natural Sciences, Volume 6, Issue 4, October 2026.ABSTRACT Purple elephant grass (Cenchrus purpureus (Schumach.) Morrone) is a valuable forage crop with potential bioactive properties that influence animal health. This study presents a comprehensive metabolomic characterization of two purple elephant grass genotypes (T441 and T515) using high‐resolution mass spectrometry (HRMS), molecular networking ...
Salva Asghar +13 more
wiley +1 more source
ChemistrySelect, Volume 11, Issue 37, 6 October 2026.Natural‐light ageing of early azo dyes and hydrazone pigments (AY36, AO7, and AR1) on cellulose‐based supports produces marked chromatic changes and distinct molecular transformations. LC–HRMS analysis of aged AY36 reveals degradation products associated with N‐oxidation, N‐dearylation, azo‐bond oxidation, and formaldehyde addition, providing a first ...
Adele Ferretti +2 more
wiley +1 more source
Smart Medicine, Volume 5, Issue 5, October 2026.AC591 and its core active component 18β‐glycyrrhetinic acid effectively alleviate cisplatin‐induced ototoxicity by binding p53 and suppressing p53‐mediated ferroptosis, representing promising agents for preventing cisplatin‐related hearing loss. ABSTRACT Cisplatin is a widely utilized chemotherapeutic agent for the treatment of malignant cancers ...
Yunhao Wu +9 more
wiley +1 more source
Structural and Functional Siderophore Remodeling by Enzymatic Delipidation
Angewandte Chemie, Volume 138, Issue 39, 21 September 2026.A surprising functional switch in bacterial siderophores was discovered through genome mining and the analysis of environmental and pathogenic Pandoraea species. Pandorachelin B, a lipocyclopeptide that promotes swarming motility, is cleaved by a specialized acylase, yielding a ring‐contracted, homodetic cyclopeptide, pandorachelin A, which exhibits ...
Elena Herzog +5 more
wiley +2 more sources
Assessment of Monomer Release From Resin Composites Following the Use of Various Modeling Liquids
Journal of Esthetic and Restorative Dentistry, Volume 38, Issue 10, Page 1933-1946, October 2026.ABSTRACT Objectives The chemical composition of resin composites and the use of modeling liquids may influence the release of residual monomer, potentially impacting biocompatibility. This in vitro study evaluated the effect of different modeling liquids on the elution of monomers from two resin composites.
Dorukcan Yıldırım +3 more
wiley +1 more source
Photoreactive Pantetheinyl Mimics Reveal Design Limitations for Crypto‐Acyl Carrier Proteins
ChemBioChem, Volume 27, Issue 18, 28 September 2026.Probes were rationally designed to capture key intramolecular interactions thorugh photocrosslinking in thiotemplated assembly lines: polyketide synthases (PKS), fatty acid synthases (FAS), and non‐ribosomal peptide synthetases (NRPS). Poor or no crosslinking was observed from these probes, highlighting current limitations of synthetic and structural ...
Anna‐Kay R. West +6 more
wiley +1 more source
Angewandte Chemie, Volume 138, Issue 39, 21 September 2026.Eine klickbare, photogeschützte 5′‐Kappe (CyCliCap) zur Herstellung von zyklischer, Click‐Cap enthaltender mRNA (Cyclic Click Cap‐mRNA), die bis zur Bestrahlung beachtlich stabil und translational stumm ist, ermöglicht die Aktivierung der Translation in Zellen zu späten Zeitpunkten mittels Lichts. ZUSAMMENFASSUNG mRNA ist eine neue Impfstofftechnologie
Bayram Terzi +6 more
wiley +1 more source
Circular Photocaged mRNA for Light‐induced Late‐stage Activation of Translation
Angewandte Chemie International Edition, Volume 65, Issue 39, 21 September 2026.A clickable photo‐caged 5′ cap (CyCliCap) allows to make Cyclic Click Cap‐containing mRNA (CyCliCap‐mRNA) which is remarkably stable and translationally muted until irradiated, allowing for late‐stage activation of translation in cells by light. ABSTRACT mRNA is a new medical modality as vaccine and raises hopes to become a protein replacement agent ...
Bayram Terzi +6 more
wiley +1 more source