Results 231 to 240 of about 255,317 (292)

Role of glutathione and cysteine in acrylamide metabolism during in vitro and in vivo digestion

Journal of the Science of Food and Agriculture, Volume 106, Issue 8, Page 5012-5020, June 2026.
Abstract Background Acrylamide, a probable human carcinogen found in thermally processed potato products, is reactive towards amino and thiol compounds. This reactivity suggests acrylamide might react with them in the gastrointestinal tract resulting in mitigation of associated risk with acrylamide.
Burçe Ataç Mogol, Choong‐In Yun, Aytül Hamzalıoğlu, Selin Çakmak, Yeşim Şensoy, Nazmiye Çitler, Eunjung Lee, Shin Young Park, Junwon Byun, Young‐Jun Kim, Sanguine Byun, Vural Gökmen   +11 more
wiley   +1 more source

LC-HRMS Lipidomic Fingerprints in Serbian Cohort of Schizophrenia Patients. [PDF]

Int J Mol Sci
Marković S, Jadranin M, Miladinović Z, Gavrilović A, Avramović N, Takić M, Tasic L, Tešević V, Mandić B.   +8 more
europepmc   +1 more source

A Robust and Universal LC–MS/MS Method for Determination of N‐Nitrosodimethylamine in Pharmaceuticals Using a C30 Column

Journal of Separation Science, Volume 49, Issue 6, June 2026.
ABSTRACT Since the 2018 valsartan recall, the genotoxic impurity N‐nitrosodimethylamine (NDMA) has been frequently detected in various pharmaceuticals. Matrix variability often complicates routine testing, requiring customized analyses. We developed a universal LC–MS/MS method enabling consistent NDMA detection across diverse pharmaceuticals ...
Byungchan An, Unyong Kim, Sumin Seo, Jiyu Kim, Chohee Jeong, Woojin Jeong, Eunjin Ko, Juhyeon Kim, Hyun‐Deok Cho, Sang Beom Han   +9 more
wiley   +1 more source

The first report from Ankara on the presence of xylazine abuse in blood and urine samples using a validated LC-HRMS method. [PDF]

Int J Legal Med
Erol Öztürk Y, Yeter O, Aslıyüksek H, Oztuna A, Sezigen S, Demirel G.   +5 more
europepmc   +1 more source

Novel Strongly Basic Molecularly Imprinted Solid‐Phase Extraction Sorbent for Simultaneous Determination of Catecholamines and Their Metabolites in Urine

Journal of Separation Science, Volume 49, Issue 6, June 2026.
ABSTRACT Catecholamines are important hormones and neuromediators in the human body. Simultaneous determination of both catecholamines and catecholamine metabolites in bodily fluids can help accurately diagnose dangerous health conditions like adrenal tumors.
Artūrs Šilaks, Antons Podjava, Laura Bernāte, Vladlens Grebnevs, Artur Maciej   +4 more
wiley   +1 more source

Untargeted LC-HRMS Metabolomics and Chemometrics of <i>Aloe vera</i> Across Diverse Geographical Origins and Cultivation Practices. [PDF]

Plants (Basel)
Anzano A, Grauso L, de Falco B, Lanzotti V.   +3 more
europepmc   +1 more source

Selective Friedel–Crafts Acylation of N‐Tosylindoles Enabling a Concise Total Synthesis of Breitfussin B

ChemistrySelect, Volume 11, Issue 24, 25 June 2026.
A practical SnCl4‐mediated Friedel–Crafts acylation of N‐tosylindoles provides regioselective access to diverse 3‐acylindoles with substrate scope across substituted indoles. The utility of this method is demonstrated in a concise total synthesis of the halogen‐rich marine natural product Breitfussin B.
Yu‐Tung Tsai, Fang‐Yi Shih, Chun‐Fu Wu, Cheng‐Kun Lin   +3 more
wiley   +1 more source

Combined detection of inhibitors of the activin receptor signaling pathways (IASPs) by means of LC-HRMS/MS for human doping control. [PDF]

Sci Rep
Sakellariou P, Walpurgis K, Thomas A, Marchand A, Miller G, Dellanna F, Thevis M.   +6 more
europepmc   +1 more source

Design, Synthesis of Novel Quinazolinone Derivatives and Evaluation of EGFR Kinase Inhibition Activity via In Vitro and In Silico Studies

Chemical Biology &Drug Design, Volume 107, Issue 6, June 2026.
Seventeen new quinazolinone derivatives were synthesized in pure form. Compound 4j showed the highest inhibitory activity against the A549 cell line and induced apoptosis via caspase‐3 activation in MCF‐7 cells. 4j inhibited EGFR enzyme twice as effectively as gefitinib.
Aybüke Züleyha Kaya, Asaf Evrim Evren, Gülşen Akalın‐Çiftçi, Leyla Yurttaş   +3 more
wiley   +1 more source

Advancing PFASs monitoring in food: from targeted SPE-LC-MS/MS to non-targeted QuEChERS-LC-HRMS approaches. [PDF]

Food Chem X
Jeannot C, Macorps N, Le Bizec B, Parinet J, Dervilly G.   +4 more
europepmc   +1 more source