Results 251 to 260 of about 330,504 (280)

Modular, Scalable, and Customizable LC-HRMS for Exposomics

In this chapter, we describe a multi-purpose, reversed-phase liquid chromatography-high-resolution mass spectrometry (LC-HRMS) workflow for acquiring high-quality, non-targeted exposomics data utilizing data-dependent acquisition (DDA) combined with the use of toxicant inclusion lists for semi-targeted analysis.
Vinicius Verri, Hernandes, Benedikt, Warth   +1 more
openaire   +2 more sources

Suzetrigine in Equestrian Sports: Optimized Extraction and LC-HRMS Detection Strategies

Rapid Communications in Mass Spectrometry
Rationale: Suzetrigine, a recently approved Na V 1.8 sodium channel blocker, shows strong potential in the treatment of neurological, psychiatric, and pain-related conditions.
Muhammed Ajeebsanu, Shino Koshy, ABDUL KHADER KARAKKA KAL, Michael Subhahar, Tajudheen Karatt, Moses Philip   +5 more
openaire   +2 more sources

Quantification of Efavirenz Hydroxymetabolites in Human Plasma Using LC-HRMS/MS

Therapeutic Drug Monitoring
Background: Efavirenz (EFV) is a drug used to treat HIV. Low plasma concentrations of EFV result in suboptimal viral suppression, whereas high concentrations can cause adverse neuropsychiatric side reactions. Some studies have identified a correlation between the plasma concentrations of EFV metabolites and neurotoxicity.
Madeleine, Pettersson Bergstrand, Sandra, Soeria-Atmadja, Victoria, Barclay, Jelena, Tolic, Lars, Navér, Lars L, Gustafsson, Anton, Pohanka   +6 more
openaire   +2 more sources

LC-HRMS- and TLC-based metabolomics for the identification and authentication of Sida rhombifolia

Journal of Chromatography B
Ensuring the authenticity and quality of Sida rhombifolia raw materials is crucial for its herbal medicinal product's consistent efficacy, quality, and safety. In this study, we developed an identification and authentication method for identifying and authenticating S. rhombifolia from Turnera subulata. T.
Uswatun, Hasanah, Eti, Rohaeti, Irmanida, Batubara, Utami Dyah, Syafitri, Rudi, Heryanto, Taopik, Ridwan, Nancy Dewi, Yuliana, Mohamad, Rafi   +7 more
openaire   +2 more sources

Identification of etazene metabolites in human urine by LC-HRMS

Toxicologie Analytique et Clinique, 2022
Nick Verougstraete, Alain Verstraete
openaire   +1 more source

A Comparative Study on Analysis of Ginsenosides in American Ginseng Root Residue by HPLC-DAD-ESI-MS and UPLC-HRMS-MS/MS

Molecules, 2022
B H Chen, Baskaran Stephen Inbaraj
exaly  

2D LC HRMS analysis of bivalirudin and its degradation products

2019
Bivalirudin is a direct thrombin inhibitor which is used as anticoagulant for patients with acute coronary syndromes or patients undergoing percutaneous coronary intervention [1]. It is a synthetic oligopeptide, consists of 20 amino acids (D-Phe-Pro-Arg-Pro-Gly-Gly-Gly-Gly-Asn-Gly- Asp- Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu), and specifically binds to ...
Galić, Nives, Vukoja, Andreja
openaire   +2 more sources

In Vitro and In Vivo Toxicometabolomics of the Synthetic Cathinone PCYP Studied by Means of LC-HRMS/MS

Metabolites, 2022
Folker Westphal, Markus R Meyer, Lea Wagmann   +2 more
exaly  

Mining of LC-HRMS data for the assessment of water treatment processes

2018
The emission of anthropogenic trace substances into the aquatic environment continuously poses challenges to water suppliers. The contamination of raw waters with organic trace substances requires complex water treatment processes to secure drinking water quality.
openaire   +1 more source

LC-HRMS Profiling and Antidiabetic, Anticholinergic, and Antioxidant Activities of Aerial Parts of Kınkor (Ferulago stellata)

Molecules, 2021
Leyla Polat Kose, Gulcin I, Saleh Alwasel   +2 more
exaly