Results 51 to 60 of about 330,504 (280)

Application of high-resolution mass spectrometry profiling towards the diagnosis and acute management of maple syrup urine disease

Molecular Genetics and Metabolism Reports
The current approach for investigating patients with suspected inborn errors of metabolism (IEMs) involves traditional targeted biochemical assays such as amino/organic acid analyses.
Rafael Garrett, Sara Pickett, Melinda J. Peters, Khadija Belhassan, Adam S. Ptolemy, Roy W.A. Peake   +5 more
doaj   +1 more source

Finnee 2024 – a Matlab toolbox for untargeted analysis of LC-HRMS datasets with MS1 scans acquired as continuous scans. [PDF]

Metabolite identification and quantification in biological samples are crucial for understanding biochemical processes, disease mechanisms, and biomarker discovery.
Guillaume, Erny
core   +1 more source

Clustomesogen Showing Sub‐Zero Liquid Crystal Properties: Supramolecular Assembly Between Cs2[Mo6Ii8(OCOC2F5)6] and Hexaethylenoxide Containing Mesogenic Dimers

Advanced Materials, EarlyView.
Associating a red‐NIR phosphorescent octahedral hexanuclear molybdenum cluster compound with hexaethyleneoxide chains bearing mesogenic units on both ends leads to an emissive hybrid liquid crystal showing mesomorphism on a very unusual temperature range down to −25°C.
Killiann Heinz, Jeanne Rebours, Zoulikha Zerrouqi, Noée Dumait, Maria Amela‐Cortes, Nikolai Scheuring, Sara Simonovska, Sebastian Marino, Max Ebert, Stéphane Cordier, Sabine Laschat, Yann Molard   +11 more
wiley   +1 more source

Untargeted lipidomics approach using LC-Orbitrap HRMS to discriminate lard from beef tallow and chicken fat for the authentification of halal

Grasas y Aceites, 2023
This research aimed to perform a lipidomics study using liquid chromatography-high resolution mass spectrometry (LC-HRMS) to identify lard, beef tallow and chicken fat. A total of 292, 345, and 403 lipid compounds were observed in lard, beef tallow, and
A. Windarsih, N.K.A. Bakar, A. Rohman, F.D.O. Riswanto, Y. Erwanto   +4 more
doaj   +1 more source

Programmable Functional Silicification of DNA Origami Nanostructures

Advanced Materials, EarlyView.
This work introduces additional functionality into silica‐coated DNA origami nanostructures using non‐standard silica precursors. A fluorescent precursor enables enhanced intracellular tracking, while a disulfide‐containing reagent yields redox‐responsive, degradable silica coatings.
Anna V. Baptist, Lasse Guericke, Philipp Mauker, Oliver Thorn‐Seshold, Amelie Heuer‐Jungemann   +4 more
wiley   +1 more source

In Situ Photopolymerization of Smectic B Liquid‐Crystalline Electrolytes from Mesogenic Phosphate–Diacrylate/Ionic Liquid Complexes for High‐Performance Soft Ionic Actuators

Advanced Robotics Research, EarlyView.
A flexible liquid‐crystalline electrolyte membrane via in situ photopolymerization of a phosphate‐functionalized mesogen, ionic liquid, and diacrylate monomer is developed. The resulting smectic B (SmB)‐phase structure enables 2D ion transport with high conductivity (10−4 S cm−1).
Chengyang Liu, Masafumi Yoshio
wiley   +1 more source

The effects of urine adulteration with oxidants before drug analysis with LC-HRMS and CEDIA

, 2022
In drug analysis, different kinds of immunoassays are often used as an initial screening for urine samples. The positive screening results are then followed by a confirmatory test, which consists of mass spectrometry methods to detect the drugs.
Nilsson, Anna
core   +2 more sources

LC-HRMS and GC-MS Profiling of Urine Free Cortisol, Cortisone, 6Β-, and 18-Hydroxycortisol for the Evaluation of Glucocorticoid and Mineralocorticoid Disorders

Biomolecules
Introduction: Urine free cortisol measurements are routinely performed to evaluate hypercortisolism. Despite their analytical inaccuracy, immunoassay-based methods are frequently used.
Gregori Casals, María Antonieta Ballesteros, Angielys Zamora, Irene Martínez, Guillermo Fernández-Varo, Mireia Mora, Felicia A. Hanzu, Manuel Morales-Ruiz   +7 more
doaj   +1 more source

Ti‐Doping Activates Adjacent Zr Sites in Bimetallic MOFs for Cooperative Phospholipid Removals in Human Biomonitoring

Advanced Science, EarlyView.
Ti‐doped Zr/Ti bimetallic MOFs activate neighboring Zr sites to selectively capture phospholipids from serum through cooperative interactions. In nontargeted screening, the material minimizes matrix interference, expands detectable feature coverage, and enables broad recovery of diverse chemical hazards, providing a powerful cleanup strategy for LC ...
Yanmin Liang, Hongyue Ma, Feier Bai, Jing Zhang, Yan Qi, Bing Shao   +5 more
wiley   +1 more source

Complete Pathway Refactoring and Combinatorial Biosynthesis of Anthracyclines for Modulation of Histone Eviction and DNA Damage Bioactivities

Angewandte Chemie, EarlyView.
A synthetic biology platform was established for the complete refactoring of complex anthracycline biosynthetic pathways in Streptomyces coelicolor using standardized, chemically synthetic DNA parts. This modular construction enabled streamlined combinatorial biosynthesis, yielding novel analogs that decouple DNA damage from chromatin damage (histone ...
Rongbin Wang, Heli Tirkkonen, Sabina Y. van der Zanden, Larissa Ponomareva, Isaline Fagon, Leslie Fève, Kendall Paige, Courtney L. Brown, Nora Schwartz, Jacob Hecht, Jennifer Nguyen, Jon S. Thorson, Jacques Neefjes, S. Eric Nybo, Khaled A. Shaaban, Mikko Metsä‐Ketelä   +15 more
wiley   +2 more sources