Results 1 to 10 of about 100,610 (290)
E1-like activating enzyme Atg7 is preferentially sequestered into p62 aggregates via its interaction with LC3-I. [PDF]
PLoS ONE, 2013 p62 is constitutively degraded by autophagy via its interaction with LC3. However, the interaction of p62 with LC3 species in the context of the LC3 lipidation process is not specified.
Wentao Gao +3 more
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The carboxyl-terminal amino acids render pro-human LC3B migration similar to lipidated LC3B in SDS-PAGE. [PDF]
PLoS ONE, 2013 LC3 is widely used marker for macroautophagy assays. After translation pro-LC3 is processed by Atg4 to expose C-terminal glycine residue for downstream conjugation reactions to accomplish the conversion of LC3-I to LC3-II. SDS-PAGE based Western blot (Wb)
Wei Wang +4 more
doaj +5 more sources
Energies, 2023 This work studies a fluidization system through cold experiments by using a mixture of rice husk and sand to investigate three parameters: type of bed distributor (perforated plate and plate with Tuyere-type injectors), sand granulometry (mean diameters ...
Fernando M. P. Balestieri +2 more
doaj +1 more source
South African Journal of Chemical Engineering, 2022 Solid carbonates can be formed by indirect mineral carbonation using the pH swing method for CO2 storage. It occurs at low temperatures and pressures in four stages: acid dissolution, purification, carbonation, and recovery.
Kely R.M. Vieira +6 more
doaj +1 more source
Energies, 2023 Global warming might be mitigated if emissions were interrupted through carbon capture technologies, as there is a significant amount of comprehensive studies on them.
Rubens C. Toledo +3 more
doaj +1 more source
LC3-associated phagocytosis [PDF]
Autophagy, 2014 A recent report from our group has described that upon engulfment of pathogens, a subset of phagosomes is formed to preserve antigens for prolonged presentation on MHC class II molecules. The distinctive feature of these particular vesicles is their coating with LC3/Atg8, a key component of the autophagy machinery. Here we discuss the possible outcomes
Romao Susana, Münz Christian
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Autophagy Reports, 2023 Epithelial cells transport substances through the cellular and paracellular pathways. The last one depends on tight junctions, particularly on claudins, the family of integral membrane proteins responsible for the permeability and selectivity of these ...
Jessica P. Campos-Blázquez +7 more
doaj +1 more source
Chromosomal mapping of the GFP-LC3 transgene in GFP-LC3 mice [PDF]
Autophagy, 2008 GFP-LC3 mice are widely used to monitor autophagy. Here, we report chromosomal mapping of the GFP.LC3 transgene in this mouse model. The transgene was located in a very distal region of chromosome 2, immediately upstream of a putative open reading frame that is thought to be a part of a pseudogene.
Akiko, Kuma, Noboru, Mizushima
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LC3 conjugation to lipid droplets
Autophagy, 2023 Macroautophagy/autophagy and lipid droplet (LD) biology are intricately linked, with autophagosome-dependent degradation of LDs in response to different signals. LDs play crucial roles in forming autophagosomes possibly by providing essential lipids and serving as a supportive autophagosome assembly platform at the endoplasmic reticulum (ER)-LD ...
Omrane, Mohyeddine +2 more
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LC3-Associated Phagocytosis and Inflammation [PDF]
Journal of Molecular Biology, 2017 LC3-associated phagocytosis (LAP) is a novel form of non-canonical autophagy where LC3 (microtubule-associated protein 1A/1B-light chain 3) is conjugated to phagosome membranes using a portion of the canonical autophagy machinery. The impact of LAP to immune regulation is best characterized in professional phagocytes, in particular macrophages, where ...
Bradlee L, Heckmann +4 more
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