Results 31 to 40 of about 100,610 (290)
LC3-associated phagocytosis: a sorting mechanism for ubiquitinated membrane proteins?
Autophagy Reports, 2022 The process of LC3-associated phagocytosis (LAP) combines elements of phagocytosis and autophagy. LAP is involved in clearance of pathogens and cell debris, antigen presentation, and immune signaling. However, the mechanistic role of LAP is incompletely understood.
Femmy C. Stempels, Geert van den Bogaart
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Detection of LC3‐Associated Phagocytosis (LAP) [PDF]
Current Protocols in Cell Biology, 2020 AbstractPhagocytes, notably macrophages, are critical sentinels of their environment, patrolling for and eradicating unwanted components. The ability of cells to process extracellular cargo in an appropriate manner is important for both clearance of the cargo and eventual return to homeostasis. Although the evolutionarily conserved pathway of autophagy
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Evidence for the involvement of lipid rafts localized at the ER-mitochondria associated membranes in autophagosome formation [PDF]
, 2016 Mitochondria-associated membranes (MAMs) are subdomains of the endoplasmic reticulum (ER) that interact with mitochondria. This membrane scrambling between ER and mitochondria appears to play a critical role in the earliest steps of autophagy.
Faggioni, Alberto +9 more
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Biomolecules, 2019 Many studies have focused on how autophagy plays an important role in intestinal homeostasis under pathological conditions. However, its role in the intestine during hibernation remains unclear.
Waseem Ali Vistro +9 more
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The blood proteome of imminent lung cancer diagnosis
Nature Communications, 2023 Identification of risk biomarkers may enhance early detection of smoking-related lung cancer. We measured between 392 and 1,162 proteins in blood samples drawn at most three years before diagnosis in 731 smoking-matched case-control sets nested within ...
The Lung Cancer Cohort Consortium (LC3)
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Düzce Tıp Fakültesi Dergisi, 2021 Aim: Acquired docetaxel (DOC) resistance of prostate cancer (PCa) is still a clinical problem. In addition to failure in chemotherapy treatment, it causes tumor recurrence.
Süleyman İlhan, Ferdi Oguz
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Disease prevention versus data privacy : using landcover maps to inform spatial epidemic models [PDF]
, 2012 The availability of epidemiological data in the early stages of an outbreak of an infectious disease is vital for modelers to make accurate predictions regarding the likely spread of disease and preferred intervention strategies.
A Estrada-Pena +28 more
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Size Effect in Lime-stone Calcined Clay Cement (LC3) incorporated Paver blocks: Mechanical and Durability Investigation [PDF]
E3S Web of ConferencesLimestone calcined clay cement (LC3) is a novel and environmentally friendly cement that is a blend of OPC clinker, calcined clay, limestone, and gypsum.
Yadav Amit +4 more
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Venetoclax inhibits autophagy in chronic lymphocytic leukemia cells
Autophagy Reports, 2023 Venetoclax (VCX) is a BCL2 inhibitor approved for treating B cell-derived leukemia, including chronic lymphocytic leukemia (CLL). VCX’s role in apoptosis induction is well-defined, whereas its other mechanistic roles need to be clarified. Autophagy is an
Yongqiang Chen +6 more
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Atg8ylation as a general membrane stress and remodeling response
Cell Stress, 2021 The yeast Atg8 protein and its paralogs in mammals, mammalian Atg8s (mAtg8s), have been primarily appreciated for their participation in autophagy. However, lipidated mAtg8s, including the most frequently used autophagosomal membrane marker LC3B, are ...
Suresh Kumar, Jingyue Jia1, Vojo Deretic
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