Results 31 to 40 of about 169,957 (248)
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Technical Evaluation Report 40: The International Learning Object Metadata Survey
International Review of Research in Open and Distributed Learning, 2004 A wide range of projects and organizations is currently making digital learning resources (learning objects) available to instructors, students, and designers via systematic, standards-based infrastructures.
Norm Friesen
doaj
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Transposing MISA Learning Scenarios into IMS Units of Learning
Journal of Interactive Media in Education, 2005 Commentary on: Chapter 17: Applying Learning Design to Supported Open Learning. (McAndrew & Weller, 2005) Abstract: This paper reports an exploratory study investigating the transposition process of a course called the Black Box into a Unit of Learning (
Ileana de la Teja +2 more
doaj +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
From Cognitive Landscapes to Digital Hyperscapes
International Review of Research in Open and Distributed Learning, 2003 The widespread diffusion of e-Learning in organizations has encouraged the discovery of more effective ways for conveying digital information to learners, for instance, via the commonly called Learning Management Systems (LMS).
José Bidarra, Ana Dias
doaj
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Understanding reusability as a key factor for open education: A review
International Review of Research in Open and Distributed Learning, 2015 This article describes both the process and the results of an extensive literature review on reusability as one of the key factors for the creation of open content in the context of open and distance learning.
Andres Chiappe, Vivian Arias
doaj +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Journal of Interactive Media in Education, 2004 : Archaeology has always been a multimedia discipline in terms of teaching and publication. From the earliest days of archaeology as an academic subject, archaeologists have used museum collections, slides, and actual site visits as well as 'chalk and ...
Lucia Nixon, Simon Price
doaj +1 more source