Results 31 to 40 of about 10,984,727 (282)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Tradisi Saprahan Sebagai Sumber Belajar Sejarah Lokal Kalimantan Barat

Fajar Historia: Jurnal Ilmu Sejarah dan Pendidikan, 2021
Lokal history content is always neglected from the national stage as seen in the history learning textbooks presented to student. The narrative that is told is a Javanese historical narrative, causing jealousy among student.
Astrini Eka Putri, Andang Firmansyah, Edwin Mirzachaerulsyah, Haris Firmansyah   +3 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

PENGELOLAAN DAN PEMANFAATAN SUMBER BELAJAR DI SEKOLAH TINGGI PARIWISATA AMPTA YOGYAKARTA

Jurnal Inovasi Teknologi Pendidikan, 2015
Penelitian ini bertujuan untuk mengetahui gambaran secara empiris mengenai pengelolaan dan pemanfaatan sumber belajar di STP AMPTA Yogyakarta. Jenis penelitian ini adalah deskriptif dengan menggunakan pendekatan kualitatif. Subyek penelitian terdiri atas
Adi Hidayat, Abdul Gafur
doaj   +1 more source

Novel Approaches for Searching and Recommending Learning Resources

Cybernetics and Information Technologies, 2023
This study proposes models for searching and recommending learning resources to meet the needs of learners, helping to achieve better student performance results. The study suggests a general architecture for searching and recommending learning resources.
Dien Tran Thanh, Thanh-Hai Nguyen, Thai-Nghe Nguyen   +2 more
doaj   +1 more source

I do, I understand: engaging distance and campus students in sustainability through active learning

Research in Learning Technology, 2023
Distance online learning connects students to education opportunities without having to be present at the institution offering the learning module. This case study involved development of a dual on-campus and distance course into a fully online course ...
Sarah J. Wakes, Linda. A. Dunn
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Higher Education: Increased and Equitable Access to Quality Learning Opportunities

, 2019
Given that many developing countries seek to increase participation in Higher Education (HE), COL will work with Ministries of Education and HE Institutions to support capacity building including the development and implementation of Open and Distance ...
Commonwealth of Learning
core   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source