Sphingolipid degradation in Leishmania (Leishmania) amazonensis.
PLoS Neglected Tropical Diseases, 2012 BackgroundHuman leishmaniasis is caused by more than 20 Leishmania species and has a wide range of symptoms. Our recent studies have demonstrated the essential role of sphingolipid degradation in the virulence of Leishmania (Leishmania) major, a species ...
Agiesh Balakrishna Pillai +3 more
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Serological reactivity of different antigenic preparations of Leishmania (Leishmania) amazonensis and the Leishmania braziliensis complex Reatividade sorológica frente a diferentes preparações antigênicas de Leishmania (Leishmania) amazonensis e do complexo Leishmania braziliensis [PDF]
Revista da Sociedade Brasileira de Medicina Tropical, 2008 Total antigen from Leishmania (Leishmania) amazonensis and isolates from the Leishmania braziliensis complex, along with their respective antigenic fractions obtained by affinity chromatography on concanavalin-A-Sepharose and jacalin-agarose columns ...
Adriano Gomes-Silva +8 more
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Experimental treatment with sodium stibogluconate of hamsters infected with Leishmania (Leishmania) chagasi and Leishmania (Leishmania) amazonensis [PDF]
Revista da Sociedade Brasileira de Medicina Tropical, 1999 The present paper reports the experimental treatment of hamsters infected with Leishmania chagasi and Leishmania amazonensis with sodium stibogluconate (20mg/kg/day x 20 days). Only with L.
Elizabeth M. de Figueiredo +2 more
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Establishment of a transdermal infection model with Leishmania amazonensis. [PDF]
Parasit VectorsAbstract Background Leishmaniasis, a parasitic disease caused by Leishmania protozoa, has various clinical forms and is endemic in Brazil.
Manhães NC +11 more
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Inhibition of Leishmania (Leishmania) amazonensis growth and infectivity by aureobasidin A [PDF]
Journal of Antimicrobial Chemotherapy, 2007 To study the effect of aureobasidin A, an inhibitor of inositol phosphorylceramide (IPC) synthase, on Leishmania growth and infectivity.Effects of aureobasidin A were determined for: (i) promastigote growth in axenic culture; (ii) promastigote infectivity in macrophage monolayers; (iii) development of footpad lesions in BALB/c mice; (iv ...
Ameria K, Tanaka +3 more
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Effects of Brazilian propolis on Leishmania amazonensis [PDF]
Memórias do Instituto Oswaldo Cruz, 2007 Leishmaniasis, an endemic parasitosis that leads to chronic cutaneous, mucocutaneous or visceral lesions, is part of those diseases, which still requires improved control tools. Propolis has shown activities against different bacteria, fungi, and parasites.
Ayres, Diana Copi +2 more
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Cohabitation of Leishmania amazonensis and Coxiella burnetii [PDF]
Trends in Microbiology, 1996 Intracellular pathogens customize the composition and function of the vacuoles they occupy, and can arrest or distort vacuolar maturation. In doubly infected cells, vacuoles that contain two different parasites can be used to test for exclusionary mechanisms, for expression of vacuolar phenotypes that permit or restrict fusion, and for the survival of ...
M, Rabinovitch, P S, Veras
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Leishmania amazonensis promastigotes in 3D Collagen I culture: an in vitro physiological environment for the study of extracellular matrix and host cell interactions [PDF]
PeerJ, 2014 Leishmania amazonensis is the causative agent of American cutaneous leishmaniasis, an important neglected tropical disease. Once Leishmania amazonensis is inoculated into the human host, promastigotes are exposed to the extracellular matrix (ECM) of the ...
Debora B. Petropolis +5 more
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Revista da Sociedade Brasileira de Medicina Tropical, 2007 New therapeutic alternatives against leishmaniasis remain a priority. The activity of azithromycin against Leishmania (Leishmania) major has been previously demonstrated.
Ángel Sinagra +5 more
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Frontiers in Immunology, 2021 Intracellular phagosomal pathogens represent a formidable challenge for innate immune cells, as, paradoxically, these phagocytic cells can act as both host cells that support pathogen replication and, when properly activated, are the critical cells that ...
Matheus B. Carneiro, Nathan C. Peters
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