Results 11 to 20 of about 10,337 (219)

Sphingolipid degradation in Leishmania (Leishmania) amazonensis.

PLoS Neglected Tropical Diseases, 2012
BackgroundHuman leishmaniasis is caused by more than 20 Leishmania species and has a wide range of symptoms. Our recent studies have demonstrated the essential role of sphingolipid degradation in the virulence of Leishmania (Leishmania) major, a species ...
Agiesh Balakrishna Pillai, Wei Xu, Ou Zhang, Kai Zhang   +3 more
doaj   +4 more sources

Serological reactivity of different antigenic preparations of Leishmania (Leishmania) amazonensis and the Leishmania braziliensis complex Reatividade sorológica frente a diferentes preparações antigênicas de Leishmania (Leishmania) amazonensis e do complexo Leishmania braziliensis [PDF]

Revista da Sociedade Brasileira de Medicina Tropical, 2008
Total antigen from Leishmania (Leishmania) amazonensis and isolates from the Leishmania braziliensis complex, along with their respective antigenic fractions obtained by affinity chromatography on concanavalin-A-Sepharose and jacalin-agarose columns ...
Adriano Gomes-Silva, Maria Aparecida Souza, Sandra Regina Afonso-Cardoso, Lívia Resende Andrade, Reynaldo Dietze, Elenice Lemos, Alejandro Belli, Silvio Favoreto Júnior, Marcelo Simão Ferreira   +8 more
doaj   +6 more sources

The Comparative Genomics and Phylogenomics of Leishmania Amazonensis Parasite [PDF]

Evolutionary Bioinformatics, 2014
Leishmaniasis is an infectious disease caused by Leishmania species. Leishmania amazonensis is a New World Leishmania species belonging to the Mexicana complex, which is able to cause all types of leishmaniasis infections. The L. amazonensis reference strain MHOM/BR/1973/M2269 was sequenced identifying 8,802 codifying sequences (CDS), most of them of ...
Tschoeke, Diogo A., Nunes, Gisele L., Jardim, Rodrigo, Lima, Joana, Dumaresq, Aline S.R., Gomes, Monete R., de Mattos Pereira, Leandro, Loureiro, Daniel R., Stoco, Patricia H., de Matos Guedes, Herbert, de Miranda, Antonio, Ruiz, Jeronimo, Pitaluga, André, Silva, Floriano P., Probst, Christian M., Dickens, Nicholas J., Mottram, Jeremy C., Grisard, Edmundo, Davila, Alberto M.R.   +18 more
openaire   +4 more sources

Analysis and chromosomal mapping of Leishmania (Leishmania) amazonensis amastigote expressed sequence tags [PDF]

Memorias do Instituto Oswaldo Cruz, 2007
The characterization of expressed sequence tags (ESTs) generated from a cDNA library of Leishmania (Leishmania) amazonensis amastigotes is described. The sequencing of 93 clones generated new L. (L.) amazonensis ESTs from which 32% are not related to any
Luciana Girotto Gentil, Fernanda Lasakosvitsch, José Franco da Silveira, Márcia Regina Machado dos Santos, Clara Lúcia Barbiéri   +4 more
doaj   +4 more sources

Role of Leishmania (Leishmania) amazonensis amastigote glycosphingolipids in macrophage infectivity [PDF]

Brazilian Journal of Medical and Biological Research, 2007
The role of glycosphingolipids (GSLs) present in amastigote forms of Leishmania (Leishmania) amazonensis during infection of macrophages was analyzed, with particular emphasis on GSLs presenting the terminal Galpss1-3Galpa disaccharide. Macrophage invasion by L.
Tanaka, Améria Kaori UNIFESP, Gorin, Philip Albert James, Takahashi, Helio Kiyoshi UNIFESP, Straus, Anita Hilda UNIFESP   +3 more
core   +8 more sources

Drosophila Model of Leishmania amazonensis Infection

BIO-PROTOCOL, 2017
This protocol describes how to generate and harvest antibody-free L. amazonensis amastigotes, and how to infect adult Drosophila melanogaster with these parasites. This model recapitulates key aspects of the interactions between Leishmania amastigotes and animal phagocytes.
Okuda, Kendi, Silverman, Neal
openaire   +6 more sources

Miltefosine induces programmed cell death in Leishmania amazonensis promastigotes [PDF]

Memorias do Instituto Oswaldo Cruz, 2011
In the current study, we evaluated the mechanism of action of miltefosine, which is the first effective and safe oral treatment for visceral leishmaniasis, in Leishmania amazonensis promastigotes.
Fernanda de Aquino Marinho, Keyla Cristiny da Silva Gonçalves, Selma Soares de Oliveira, Ana-Carolina de Siqueira Couto de Oliveira, Maria Bellio, Claudia Masini d'Avila-Levy, André Luis Souza dos Santos, Marta Helena Branquinha   +7 more
doaj   +5 more sources

Experimental treatment with sodium stibogluconate of hamsters infected with Leishmania (Leishmania) chagasi and Leishmania (Leishmania) amazonensis [PDF]

Revista da Sociedade Brasileira de Medicina Tropical, 1999
The present paper reports the experimental treatment of hamsters infected with Leishmania chagasi and Leishmania amazonensis with sodium stibogluconate (20mg/kg/day x 20 days). Only with L.
Elizabeth M. de Figueiredo, Jaime Costa e Silva, Reginaldo P. Brazil   +2 more
doaj   +4 more sources

Inhibition of Leishmania (Leishmania) amazonensis growth and infectivity by aureobasidin A [PDF]

Journal of Antimicrobial Chemotherapy, 2007
To study the effect of aureobasidin A, an inhibitor of inositol phosphorylceramide (IPC) synthase, on Leishmania growth and infectivity.Effects of aureobasidin A were determined for: (i) promastigote growth in axenic culture; (ii) promastigote infectivity in macrophage monolayers; (iii) development of footpad lesions in BALB/c mice; (iv ...
Ameria K, Tanaka, Valderez B, Valero, Helio K, Takahashi, Anita H, Straus   +3 more
openaire   +2 more sources

Establishment of a transdermal infection model with Leishmania amazonensis. [PDF]

Parasit Vectors
Abstract Background Leishmaniasis, a parasitic disease caused by Leishmania protozoa, has various clinical forms and is endemic in Brazil.
Manhães NC, Praxedes H, Da-Rocha AA, de Almeida DB, Dos Santos IB, da Silva-Junior EB, Covre L, Freire-de-Lima CG, Oliveira Gomes DC, da-Cruz AM, da Fonseca-Martins AM, de Matos Guedes HL.   +11 more
europepmc   +4 more sources