Results 31 to 40 of about 6,625 (182)

The diverse and dynamic nature of Leishmania parasitophorous vacuoles studied by multidimensional imaging. [PDF]

PLoS Neglected Tropical Diseases, 2012
An important area in the cell biology of intracellular parasitism is the customization of parasitophorous vacuoles (PVs) by prokaryotic or eukaryotic intracellular microorganisms.
Fernando Real, Renato A Mortara
doaj   +1 more source

In vitro leishmanicidal effect of Yangambin and Epi-yangambin lignans isolated from Ocotea fasciculata (Nees) Mez

Frontiers in Cellular and Infection Microbiology, 2023
IntroductionYangambin and epi-yangambin are the main lignans found in Louro-de-Cheiro [Ocotea fasciculata (Nees) Mez], a tree native to the Atlantic forests of northeastern Brazil whose leaves and bark are widely used in folk medicine.
Jéssica Rebouças-Silva, Jéssica Rebouças-Silva, Gabriel Farias Santos, José Maria Barbosa Filho, Andresa A. Berretta, Franciane Marquele-Oliveira, Valéria M. Borges, Valéria M. Borges   +7 more
doaj   +1 more source

Experimental transmission of Leishmania (Leishmania) amazonensis to immunosuppressed mice through the bite of Lutzomyia longipalpis (Diptera: Psychodidae) results in cutaneous leishmaniasis

Revista do Instituto de Medicina Tropical de São Paulo, 2021
Lutzomyia longipalpis is the natural vector of Leishmania (Leishmania) infantum, but it is also permissive for several Leishmania species that are related to cutaneous leishmaniasis (CL). Maranhao State (Northeast of Brazil) is endemic for CL and has the
Rosa Cristina Ribeiro da Silva, Léo Nava Piorsky Dominici Cruz, João Manoel da Silva Coutinho, Carlos Eduardo Fonseca-Alves, José Manuel Macário Rebêlo, Silma Regina Ferreira Pereira   +5 more
doaj   +1 more source

The Comparative Genomics and Phylogenomics of Leishmania Amazonensis Parasite [PDF]

Evolutionary Bioinformatics, 2014
Leishmaniasis is an infectious disease caused by Leishmania species. Leishmania amazonensis is a New World Leishmania species belonging to the Mexicana complex, which is able to cause all types of leishmaniasis infections. The L. amazonensis reference strain MHOM/BR/1973/M2269 was sequenced identifying 8,802 codifying sequences (CDS), most of them of ...
Tschoeke, Diogo A., Nunes, Gisele L., Jardim, Rodrigo, Lima, Joana, Dumaresq, Aline S.R., Gomes, Monete R., de Mattos Pereira, Leandro, Loureiro, Daniel R., Stoco, Patricia H., de Matos Guedes, Herbert, de Miranda, Antonio, Ruiz, Jeronimo, Pitaluga, André, Silva, Floriano P., Probst, Christian M., Dickens, Nicholas J., Mottram, Jeremy C., Grisard, Edmundo, Davila, Alberto M.R.   +18 more
openaire   +3 more sources

Experimental infection of Lutzomyia longipalpis fed on a patient with cutaneous leishmaniasis due to Leishmania mexicana amazonensis

Memorias do Instituto Oswaldo Cruz, 1986
The authors were able to infect phlebotomine sandflies on a human case of American Cutaneous Leishmaniasis by feeding females of Lutzomyia longipalpis on a patient with a lesion due to Leishmania mexicana amazonensis.Os autores lograram infectar ...
Leonidas M. Deane, Elizabeth Ferreira Rangel, Manoel Paes-Oliveira, Gabriel Grimaldi Junior, Hooman Momen, Nataly de Souza, Eduardo D. Wermelinger, André F. Barbosa   +7 more
doaj   +1 more source

Fusion between Leishmania amazonensis and Leishmania major parasitophorous vacuoles: live imaging of coinfected macrophages. [PDF]

PLoS Neglected Tropical Diseases, 2010
Protozoan parasites of the genus Leishmania alternate between flagellated, elongated extracellular promastigotes found in insect vectors, and round-shaped amastigotes enclosed in phagolysosome-like Parasitophorous Vacuoles (PVs) of infected mammalian ...
Fernando Real, Renato A Mortara, Michel Rabinovitch   +2 more
doaj   +1 more source

Drosophila Model of Leishmania amazonensis Infection

BIO-PROTOCOL, 2017
This protocol describes how to generate and harvest antibody-free L. amazonensis amastigotes, and how to infect adult Drosophila melanogaster with these parasites. This model recapitulates key aspects of the interactions between Leishmania amastigotes and animal phagocytes.
Okuda, Kendi, Silverman, Neal
openaire   +5 more sources

In Vitro and In Vivo Activity of a Palladacycle Complex on Leishmania (Leishmania) amazonensis

PLoS Neglected Tropical Diseases, 2012
Antitumor cyclopalladated complexes with low toxicity to laboratory animals have shown leishmanicidal effect. These findings stimulated us to test the leishmanicidal property of one palladacycle compound called DPPE 1.2 on Leishmania (Leishmania) amazonensis, an agent of simple and diffuse forms of cutaneous leishmaniasis in the Amazon region, Brazil ...
Carolina de Siqueira Paladi, Isabella Aparecida Salerno Pimentel, Simone Katz, Rodrigo L O R Cunha, Wagner Alves de Souza Judice, Antonio C F Caires, Clara Lúcia Barbiéri   +6 more
openaire   +4 more sources

Inhibition of growth of Leishmania mexicana mexicana by Leishmania mexicana amazonensis during "in vitro" co-cultivation Inibição do crescimento de Leishmania mexicana mexicana por Leishmania mexicana amazonensis durante o co-cultivo "in vitro"

Memorias do Instituto Oswaldo Cruz, 1987
Inhibition of one Leishmania subspecies by exometabolites of another subspecies, a phenomenon not previously reported, is suggested by our recent observations in cell cloning experiments with Leishmania mexicana mexicana and Leishmania mexicana ...
Raquel S. Pacheco, Gabriel Grimaldi Júnior, Carlos M. Morel   +2 more
doaj   +1 more source

Murine T Cell‐Dependent Response Affects Leishmania amazonensis Amastigote Survival and Virulence

Cell Biology International, Volume 50, Issue 8, August 2026.
ABSTRACT Our group has previously described the infection course of Leishmania amazonensis in BALB/c and BALB/cnu/nu mice, which have distinct T‐cell dependent responses. In this study, lesion‐derived amastigotes exhibited differential protein expression in a host‐dependent manner.
Gustavo Henrique Corrêa Soares, Gustavo Rolim Barbosa, Beatriz Simonsen Stolf   +2 more
wiley   +1 more source