Results 31 to 40 of about 10,337 (219)

"Leishmania infantum" : molecular analysis for identification of potential virulence factors and genes of diagnostic use [PDF]

open access: yes, 2004
Leishmania infantum is the causative agents of zoonotic visceral leishmaniasis, a fatal disease if left untreated. In Southern Europe, the number of HIV/Leishmania infantum co-infections is increasing and becomes an emerging concern for the public health.
Niederwieser, Igor
core   +1 more source

Leishmania amazonensis Infection in Nude Mice.

open access: yesExperimental Animals, 1999
Leishmania amazonensis is an intracellular protozoan parasite of macrophages. Cutaneous leishmaniasis in an immunocompetent host begins as papules or nodules followed by ulceration at the site of promastigote inoculation. In this study, the pathological changes of cutaneous leishmaniasis lesions in T cell deficient nude mice were examined.
TERABE, Masaki   +5 more
openaire   +3 more sources

Vaccination of C57BL/10 mice against cutaneous leishmaniasis using killed promastigotes of different strains and species of Leishmania Vacinação de camundongos C57BL/10 contra leishmaniose com promastigotas mortas de diferentes cepas e espécies de Leishmania

open access: yesRevista da Sociedade Brasileira de Medicina Tropical, 2002
Antigenic extracts from five Leishmania stocks were used to vaccinate C57BL/10 mice. The Leishvacin® and PH8 monovalent vaccine yielded the highest IFN-gamma levels in the supernatants of spleen cell culture from vaccinated animals.
Wilson Mayrink   +6 more
doaj   +1 more source

Synthesis, Leishmanicidal Activity and Theoretical Evaluations of a Series of Substituted bis-2-Hydroxy-1,4-Naphthoquinones

open access: yesMolecules, 2014
A series of eight substituted bis-2-hydroxy-1,4-naphthoquinone derivatives was synthesized through lawsone condensation with various aromatic and aliphatic aldehydes under mild acidic conditions.
Morgana V. de Araújo   +9 more
doaj   +1 more source

The role of leishmania proteophosphoglycans in sand fly transmission and infection of the Mammalian host. [PDF]

open access: yes, 2012
Leishmania are transmitted by the bite of their sand fly vector and this has a significant influence on the virulence of the resulting infection. From our studies into the interaction between parasite, vector, and host we have uncovered an important ...
Rogers, Matthew E   +2 more
core   +1 more source

BALB/c mice deficient in CD4(+) T cell IL-4R alpha expression control Leishmania mexicana load although female but not male mice develop a healer phenotype [PDF]

open access: yes, 2011
Immunologically intact BALB/c mice infected with Leishmania mexicana develop non-healing progressively growing lesions associated with a biased Th2 response while similarly infected IL-4R alpha-deficient mice fail to develop lesions and develop a robust ...
Owain R Millington   +29 more
core   +1 more source

Immune responses induced by a Leishmania (Leishmania) amazonensis recombinant antigen in mice and lymphocytes from vaccinated subjects

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 1997
In the search for Leishmania recombinant antigens that can be used as a vaccine against American Cutaneous Leishmaniasis, we identified a Leishmania (Leishmania) amazonensis recombinant protein of 33 kD (Larp33) which is recognized by antibodies and ...
Ana Paula FERNANDES   +10 more
doaj   +1 more source

In vitro leishmanicidal effect of Yangambin and Epi-yangambin lignans isolated from Ocotea fasciculata (Nees) Mez

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
IntroductionYangambin and epi-yangambin are the main lignans found in Louro-de-Cheiro [Ocotea fasciculata (Nees) Mez], a tree native to the Atlantic forests of northeastern Brazil whose leaves and bark are widely used in folk medicine.
Jéssica Rebouças-Silva   +7 more
doaj   +1 more source

Chicken blood provides a suitable meal for the sand fly Lutzomyia longipalpis and does not inhibit Leishmania development in the gut [PDF]

open access: yes, 2010
Background The aim of this study was to address the role of chickens as bloodmeal sources for female Lutzomyia longipalpis and to test whether chicken blood is harmful to Leishmania parasite development within the sand flies.
Diaz-Albiter Hector M   +27 more
core   +1 more source

The diverse and dynamic nature of Leishmania parasitophorous vacuoles studied by multidimensional imaging. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2012
An important area in the cell biology of intracellular parasitism is the customization of parasitophorous vacuoles (PVs) by prokaryotic or eukaryotic intracellular microorganisms.
Fernando Real, Renato A Mortara
doaj   +1 more source

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