Results 31 to 40 of about 59,340 (183)

Vaccination of C57BL/10 mice against cutaneous leishmaniasis using killed promastigotes of different strains and species of Leishmania Vacinação de camundongos C57BL/10 contra leishmaniose com promastigotas mortas de diferentes cepas e espécies de Leishmania

Revista da Sociedade Brasileira de Medicina Tropical, 2002
Antigenic extracts from five Leishmania stocks were used to vaccinate C57BL/10 mice. The Leishvacin® and PH8 monovalent vaccine yielded the highest IFN-gamma levels in the supernatants of spleen cell culture from vaccinated animals.
Wilson Mayrink, Gilmara Cristina dos Santos, Vicente de Paulo Coelho Peixoto de Toledo, Tânia Mara Pinto Dabés Guimarães, George Luis Lins Machado-Coelho, Odair Genaro, Carlos Alberto da Costa   +6 more
doaj   +1 more source

Leishmania (Leishmania) amazonensis Infection in Mice Treated With FTY720

Transplantation Proceedings, 2010
In transplantation, parasite diseases are transmitted from the donor, or appear as de novo infections, or activate from a dormant insource as a consequence of immunosuppression. Clinical findings have shown that an intact immune system is crucial to prevent recurrence of Leishmania infection.
Lopes, C. T. UNIFESP, De Paula, Daisy Maria Bentes UNIFESP, Cury, P. M., Valero-Lapchik, V. B. UNIFESP, Bueno, V. UNIFESP   +4 more
openaire   +3 more sources

Synthesis, Leishmanicidal Activity and Theoretical Evaluations of a Series of Substituted bis-2-Hydroxy-1,4-Naphthoquinones

Molecules, 2014
A series of eight substituted bis-2-hydroxy-1,4-naphthoquinone derivatives was synthesized through lawsone condensation with various aromatic and aliphatic aldehydes under mild acidic conditions.
Morgana V. de Araújo, Patricia S. O. de Souza, Aline C. de Queiroz, Carolina B. B. da Matta, Anderson Brandão Leite, Amanda Evelyn da Silva, José A. A. de França, Tania M. S. Silva, Celso A. Camara, Magna S. Alexandre-Moreira   +9 more
doaj   +1 more source

Role of Leishmania (Leishmania) amazonensis amastigote glycosphingolipids in macrophage infectivity [PDF]

Brazilian Journal of Medical and Biological Research, 2007
The role of glycosphingolipids (GSLs) present in amastigote forms of Leishmania (Leishmania) amazonensis during infection of macrophages was analyzed, with particular emphasis on GSLs presenting the terminal Galpss1-3Galpa disaccharide. Macrophage invasion by L.
Tanaka, Améria Kaori UNIFESP, Gorin, Philip Albert James, Takahashi, Helio Kiyoshi UNIFESP, Straus, Anita Hilda UNIFESP   +3 more
openaire   +6 more sources

Immune responses induced by a Leishmania (Leishmania) amazonensis recombinant antigen in mice and lymphocytes from vaccinated subjects

Revista do Instituto de Medicina Tropical de São Paulo, 1997
In the search for Leishmania recombinant antigens that can be used as a vaccine against American Cutaneous Leishmaniasis, we identified a Leishmania (Leishmania) amazonensis recombinant protein of 33 kD (Larp33) which is recognized by antibodies and ...
Ana Paula FERNANDES, Elizabeth Cortez HERRERA, Wilson MAYRINK, Ricardo T. GAZZINELLI, Wen Yu LIU, Carlos Alberto da COSTA, Carlos Alberto Pereira TAVARES, Maria Norma MELO, Marilene Susan Marques MICHALICK, Reiner GENTZ, Evaldo NASCIMENTO   +10 more
doaj   +1 more source

The diverse and dynamic nature of Leishmania parasitophorous vacuoles studied by multidimensional imaging. [PDF]

PLoS Neglected Tropical Diseases, 2012
An important area in the cell biology of intracellular parasitism is the customization of parasitophorous vacuoles (PVs) by prokaryotic or eukaryotic intracellular microorganisms.
Fernando Real, Renato A Mortara
doaj   +1 more source

In vitro leishmanicidal effect of Yangambin and Epi-yangambin lignans isolated from Ocotea fasciculata (Nees) Mez

Frontiers in Cellular and Infection Microbiology, 2023
IntroductionYangambin and epi-yangambin are the main lignans found in Louro-de-Cheiro [Ocotea fasciculata (Nees) Mez], a tree native to the Atlantic forests of northeastern Brazil whose leaves and bark are widely used in folk medicine.
Jéssica Rebouças-Silva, Jéssica Rebouças-Silva, Gabriel Farias Santos, José Maria Barbosa Filho, Andresa A. Berretta, Franciane Marquele-Oliveira, Valéria M. Borges, Valéria M. Borges   +7 more
doaj   +1 more source

Real-time imaging of Leishmania mexicana-infected early phagosomes: a study using primary macrophages generated from green fluorescent protein-Rab5 transgenic mice [PDF]

, 2009
The small GTPase Rab5 is a key regulator of endosome/phagosome maturation and in intravesicular infections marks a phagosome stage at which decisions over pathogen replication or destruction are integrated.
Paape, Daniel, Blackburn, Clare, Lippuner, C., Smith, Andrew, Smith, A. J., Paterou, A., Brand, J., Richardson, Melville, Richardson, M., Blackburn, C., Andrew J. Smith, Volker Brinkmann, Brinkmann, Volker, Janko Brand, Smith, A., Brinkmann, V., Daniel Paape, Toni Aebischer, Brand, Janko, Hoffmann, Kirstin, Hoffmann, K., Athina Paterou, Kirstin Hoffmann, Aebischer, Toni, Paterou, Athina, Paape, D., Clare Blackburn, Smith, Andrew J., Melville Richardson, Aebischer, T., Christoph Lippuner, Lippuner, Christoph   +31 more
core   +1 more source

Experimental transmission of Leishmania (Leishmania) amazonensis to immunosuppressed mice through the bite of Lutzomyia longipalpis (Diptera: Psychodidae) results in cutaneous leishmaniasis

Revista do Instituto de Medicina Tropical de São Paulo, 2021
Lutzomyia longipalpis is the natural vector of Leishmania (Leishmania) infantum, but it is also permissive for several Leishmania species that are related to cutaneous leishmaniasis (CL). Maranhao State (Northeast of Brazil) is endemic for CL and has the
Rosa Cristina Ribeiro da Silva, Léo Nava Piorsky Dominici Cruz, João Manoel da Silva Coutinho, Carlos Eduardo Fonseca-Alves, José Manuel Macário Rebêlo, Silma Regina Ferreira Pereira   +5 more
doaj   +1 more source

Experimental infection of Lutzomyia longipalpis fed on a patient with cutaneous leishmaniasis due to Leishmania mexicana amazonensis

Memorias do Instituto Oswaldo Cruz, 1986
The authors were able to infect phlebotomine sandflies on a human case of American Cutaneous Leishmaniasis by feeding females of Lutzomyia longipalpis on a patient with a lesion due to Leishmania mexicana amazonensis.Os autores lograram infectar ...
Leonidas M. Deane, Elizabeth Ferreira Rangel, Manoel Paes-Oliveira, Gabriel Grimaldi Junior, Hooman Momen, Nataly de Souza, Eduardo D. Wermelinger, André F. Barbosa   +7 more
doaj   +1 more source