Results 21 to 30 of about 6,625 (182)

Osteopontin in the host response to Leishmania amazonensis [PDF]

open access: yesBMC Microbiology, 2019
Leishmania (L.) spp are intracellular eukaryotic parasites responsible for cutaneous or visceral leishmaniasis, replicating predominantly in macrophages (MF). In C57BL/6 mice virulence with L. amazonensis has been associated with inhibition of Th1 immune responses and an uncontrolled lesion development, whereas DBA/2 mice control any lesion.
Giraud, Emilie   +5 more
openaire   +3 more sources

Effect of 3-Carene and the Micellar Formulation on Leishmania (Leishmania) amazonensis

open access: yesTropical Medicine and Infectious Disease, 2023
Leishmaniases are neglected tropical diseases caused by obligate intracellular protozoa of the genus Leishmania. The drugs used in treatment have a high financial cost, a long treatment time, high toxicity, and variable efficacy. 3-Carene (3CR) is a hydrocarbon monoterpene that has shown in vitro activity against some Leishmania species; however, it ...
Audrey Rouse Soares Tavares Silva   +10 more
openaire   +3 more sources

Leishmania (Leishmania) amazonensis Infection in Mice Treated With FTY720

open access: yesTransplantation Proceedings, 2010
In transplantation, parasite diseases are transmitted from the donor, or appear as de novo infections, or activate from a dormant insource as a consequence of immunosuppression. Clinical findings have shown that an intact immune system is crucial to prevent recurrence of Leishmania infection.
Lopes, C. T. UNIFESP   +4 more
openaire   +3 more sources

Analysis and chromosomal mapping of Leishmania (Leishmania) amazonensis amastigote expressed sequence tags

open access: yesMemorias do Instituto Oswaldo Cruz, 2007
The characterization of expressed sequence tags (ESTs) generated from a cDNA library of Leishmania (Leishmania) amazonensis amastigotes is described. The sequencing of 93 clones generated new L. (L.) amazonensis ESTs from which 32% are not related to any
Luciana Girotto Gentil   +4 more
doaj   +1 more source

Leukocyte Behavior in Mesenteric Microcirculation upon Experimental By Leishmania Spp. in BALB/c Mice

open access: yesIranian Journal of Parasitology, 2021
Background: We aimed to determine the cellular recruitment (leukocyte rolling and adhesion) by which the Leishmania (Viannia) braziliensis, L. (Leishmania) amazonensis, and L. (Leishmania) major species in the mesenteric microcirculation of BALB/c mice.
Herintha Coeto Neitzke-Abreu   +9 more
doaj  

Leishmania amazonensis Infection in Nude Mice.

open access: yesExperimental Animals, 1999
Leishmania amazonensis is an intracellular protozoan parasite of macrophages. Cutaneous leishmaniasis in an immunocompetent host begins as papules or nodules followed by ulceration at the site of promastigote inoculation. In this study, the pathological changes of cutaneous leishmaniasis lesions in T cell deficient nude mice were examined.
TERABE, Masaki   +5 more
openaire   +3 more sources

Vaccination of C57BL/10 mice against cutaneous leishmaniasis using killed promastigotes of different strains and species of Leishmania Vacinação de camundongos C57BL/10 contra leishmaniose com promastigotas mortas de diferentes cepas e espécies de Leishmania

open access: yesRevista da Sociedade Brasileira de Medicina Tropical, 2002
Antigenic extracts from five Leishmania stocks were used to vaccinate C57BL/10 mice. The Leishvacin® and PH8 monovalent vaccine yielded the highest IFN-gamma levels in the supernatants of spleen cell culture from vaccinated animals.
Wilson Mayrink   +6 more
doaj   +1 more source

Synthesis, Leishmanicidal Activity and Theoretical Evaluations of a Series of Substituted bis-2-Hydroxy-1,4-Naphthoquinones

open access: yesMolecules, 2014
A series of eight substituted bis-2-hydroxy-1,4-naphthoquinone derivatives was synthesized through lawsone condensation with various aromatic and aliphatic aldehydes under mild acidic conditions.
Morgana V. de Araújo   +9 more
doaj   +1 more source

Immune responses induced by a Leishmania (Leishmania) amazonensis recombinant antigen in mice and lymphocytes from vaccinated subjects

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 1997
In the search for Leishmania recombinant antigens that can be used as a vaccine against American Cutaneous Leishmaniasis, we identified a Leishmania (Leishmania) amazonensis recombinant protein of 33 kD (Larp33) which is recognized by antibodies and ...
Ana Paula FERNANDES   +10 more
doaj   +1 more source

Role of Leishmania (Leishmania) amazonensis amastigote glycosphingolipids in macrophage infectivity [PDF]

open access: yesBrazilian Journal of Medical and Biological Research, 2007
The role of glycosphingolipids (GSLs) present in amastigote forms of Leishmania (Leishmania) amazonensis during infection of macrophages was analyzed, with particular emphasis on GSLs presenting the terminal Galpss1-3Galpa disaccharide. Macrophage invasion by L.
Tanaka, Améria Kaori UNIFESP   +3 more
openaire   +6 more sources

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