Results 41 to 50 of about 16,640 (230)

In vitro leishmanicidal effect of Yangambin and Epi-yangambin lignans isolated from Ocotea fasciculata (Nees) Mez

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
IntroductionYangambin and epi-yangambin are the main lignans found in Louro-de-Cheiro [Ocotea fasciculata (Nees) Mez], a tree native to the Atlantic forests of northeastern Brazil whose leaves and bark are widely used in folk medicine.
Jéssica Rebouças-Silva   +7 more
doaj   +1 more source

The Role of Cytoplasmic mRNA Cap-Binding Protein Complexes in Trypanosoma brucei and Other Trypanosomatids. [PDF]

open access: yes, 2017
Trypanosomatid protozoa are unusual eukaryotes that are well known for having unusual ways of controlling their gene expression. The lack of a refined mode of transcriptional control in these organisms is compensated by several post-transcriptional ...
Campbell, David A   +3 more
core   +2 more sources

Leishmania (Leishmania) amazonensis Infection in Mice Treated With FTY720

open access: yesTransplantation Proceedings, 2010
In transplantation, parasite diseases are transmitted from the donor, or appear as de novo infections, or activate from a dormant insource as a consequence of immunosuppression. Clinical findings have shown that an intact immune system is crucial to prevent recurrence of Leishmania infection.
Lopes, C. T. UNIFESP   +4 more
openaire   +3 more sources

Experimental transmission of Leishmania (Leishmania) amazonensis to immunosuppressed mice through the bite of Lutzomyia longipalpis (Diptera: Psychodidae) results in cutaneous leishmaniasis

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 2021
Lutzomyia longipalpis is the natural vector of Leishmania (Leishmania) infantum, but it is also permissive for several Leishmania species that are related to cutaneous leishmaniasis (CL). Maranhao State (Northeast of Brazil) is endemic for CL and has the
Rosa Cristina Ribeiro da Silva   +5 more
doaj   +1 more source

Experimental infection of Lutzomyia longipalpis fed on a patient with cutaneous leishmaniasis due to Leishmania mexicana amazonensis

open access: yesMemorias do Instituto Oswaldo Cruz, 1986
The authors were able to infect phlebotomine sandflies on a human case of American Cutaneous Leishmaniasis by feeding females of Lutzomyia longipalpis on a patient with a lesion due to Leishmania mexicana amazonensis.Os autores lograram infectar ...
Leonidas M. Deane   +7 more
doaj   +1 more source

Fusion between Leishmania amazonensis and Leishmania major parasitophorous vacuoles: live imaging of coinfected macrophages. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2010
Protozoan parasites of the genus Leishmania alternate between flagellated, elongated extracellular promastigotes found in insect vectors, and round-shaped amastigotes enclosed in phagolysosome-like Parasitophorous Vacuoles (PVs) of infected mammalian ...
Fernando Real   +2 more
doaj   +1 more source

Iron metabolism in trypanosomatids, and its crucial role in infection. [PDF]

open access: yes, 2010
Iron is almost ubiquitous in living organisms due to the utility of its redox chemistry. It is also dangerous as it can catalyse the formation of reactive free radicals - a classical double-edged sword.
Kelly, JM, Taylor, MC
core   +1 more source

Inhibition of Leishmania (Leishmania) amazonensis growth and infectivity by aureobasidin A [PDF]

open access: yesJournal of Antimicrobial Chemotherapy, 2007
To study the effect of aureobasidin A, an inhibitor of inositol phosphorylceramide (IPC) synthase, on Leishmania growth and infectivity.Effects of aureobasidin A were determined for: (i) promastigote growth in axenic culture; (ii) promastigote infectivity in macrophage monolayers; (iii) development of footpad lesions in BALB/c mice; (iv ...
Ameria K, Tanaka   +3 more
openaire   +2 more sources

Arginase expression modulates nitric oxide production in Leishmania (Leishmania) amazonensis

open access: yesPLOS ONE, 2017
Arginase is an enzyme that converts L-arginine to urea and L-ornithine, an essential substrate for the polyamine pathway supporting Leishmania (Leishmania) amazonensis replication and its survival in the mammalian host. L-arginine is also the substrate of macrophage nitric oxide synthase 2 (NOS2) to produce nitric oxide (NO) that kills the parasite ...
Stephanie Maia Acuña   +6 more
openaire   +4 more sources

In silico predicted epitopes from the COOH-terminal extension of cysteine proteinase B inducing distinct immune responses during Leishmania (Leishmania) amazonensis experimental murine infection [PDF]

open access: yes, 2011
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Molecular e Doenças Endêmicas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Molecular e Doenças Endêmicas.
Bernardo AS Pereira   +8 more
core   +2 more sources

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