Results 61 to 70 of about 16,640 (230)
The FEBS Journal, Volume 293, Issue 6, Page 1681-1707, March 2026.Heteromeric cis‐prenyltransferases (CPT) are indispensable for dolichol synthesis and protein N‐glycosylation in most eukaryotes. The catalytic subunits are strongly conserved throughout evolution, in contrast to the evolutionarily variable accessory subunits. The POC1 protein from Paramecium tetraurelia is the smallest identified CPT‐accessory subunit
Agnieszka Onysk +8 more
wiley +1 more source
Cell structure and cytokinesis alterations in multidrug-resistant Leishmania (Leishmania) amazonensis [PDF]
Parasitology Research, 2004 Multidrug-resistant Leishmania (Leishmania) amazonensis may be obtained by in vitro selection with vinblastine. In order to determine whether this phenotype is linked to structural alterations, we analyzed the cell architecture by electron microscopy. The vinblastine resistant CL2 clone of L.
V M, Borges +3 more
openaire +2 more sources
Revista do Instituto de Medicina Tropical de São Paulo, 2022 Visceral leishmaniasis (VL) is mainly caused by Leishmania (Leishmania) donovani and Leishmania (L.) infantum; however, other Leishmania species have been associated with VL. We report a case of a patient simultaneously diagnosed with VL caused by Leishmania (L.) amazonensis and Hodgkin's lymphoma.
Victor Bertolo Gomes Porto +9 more
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Antileishmanial activity and evaluation of the mechanism of action of strychnobiflavone flavonoid isolated from Strychnos pseudoquina against Leishmania infantum [PDF]
, 2016 © 2015, Springer-Verlag Berlin Heidelberg. The present study aimed to investigate the in vitro antileishmanial activity of strychnobiflavone flavonoid against Leishmania infantum, as well as its mechanism of action, and evaluate the ex vivo ...
Coelho, Eduardo A. F. +2 more
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Photochemistry and Photobiology, Volume 102, Issue 2, Page 480-488, March/April 2026.In this study, we developed giant plasma membrane vesicles (GPMVs) from Leishmania amazonensis promastigote membranes to investigate the role of protein‐embedded membranes in methylene blue (MB) photooxidation. Upon MB photoactivation in model lipid membranes (giant unilamellar vesicles, GUVs), a distinct photooxidation effect was observed, marked by ...
Maressa D. F. de Souza +3 more
wiley +1 more source
2-Substituted quinoline alkaloids as potential antileishmanial drugs [PDF]
, 1993 Ten 2-substituted quinoline alkaloids isolated from a plant used for treatment of New World cutaneous leishmaniasis have antileishmanial in vitro activities against the extracellular forms of Leishmania spp.
Barrios, A.A. +5 more
core +1 more source
ChemMedChem, Volume 21, Issue 4, 25 February 2026.Schematic representation depicting the influence of phosphine ligand identity on the biological and physicochemical characteristics of Pt(II) complexes: PTA promotes antileishmanial activity, PPh2(Php–COOH) strengthens antiviral activity, and TCEP enhances fluorescence.
Antonio A. de Oliveira‐Neto +12 more
wiley +1 more source
PLoS Neglected Tropical Diseases, 2019 BackgroundLeishmania parasites are transmitted to vertebrate hosts by phlebotomine sandflies and, in humans, may cause tegumentary or visceral leishmaniasis.
Carolina Torturella Rath +11 more
doaj +1 more source
Microorganisms, 2021 Leishmania amazonensis parasites are etiological agents of cutaneous leishmaniasis in the New World. BALB/c mice are highly susceptible to L. amazonensis challenge due to their inability to mount parasite-dependent IFN-γ-mediated responses.
Manuel Soto +6 more
doaj +1 more source
Organic Light‐Emitting Diode in Phototherapy Applications
Advanced Photonics Research, Volume 7, Issue 2, February 2026.This article systematically reviews the development of organic light‐emitting diodes (OLEDs) in phototherapy, constructs a technical framework, and establishes a multidimensional knowledge graph encompassing indications, wavelengths, and light intensity.
Yingguang Zhu +9 more
wiley +1 more source