Características epidemiológicas da leishmaniose tegumentar americana em uma região endêmica do Estado da Bahia : II leishmaniose canina [PDF]
Um inquérito em cães realizado na região de Três Braços, Bahia, mostrou que 3,0% de 98 animais tinham amastigotas em lesões de pele. Parasitos não foram encontrados em pele normal da orelha.
Barretto, Air C. +5 more
core +3 more sources
Piplartine as an Innovative Natural Product With Dual Antiparasitic and Immunomodulatory Actions
Neglected tropical diseases (NTDs) remain a major global health burden, disproportionately affecting low‐ and middle‐income regions and demanding innovative therapeutic strategies. This review summarizes current evidence on piplartine (piperlongumine), a naturally occurring amide from Piper species with broad antiparasitic and immunomodulatory ...
Lucas Fukui-Silva +4 more
wiley +1 more source
Sequence analysis of the 3-untranslated region of HSP70 (type I) genes in the genus Leishmania: Its usefulness as a molecular marker for species identification [PDF]
Background: The Leishmaniases are a group of clinically diverse diseases caused by parasites of the genus Leishmania. To distinguish between species is crucial for correct diagnosis and prognosis as well as for treatment decisions.
Cañavate, Carmen +5 more
core +1 more source
The P2X7 Receptor and Its Relation to Neglected Tropical Diseases: Focusing on Chagas Disease
Chagas disease, caused by Trypanosoma cruzi, is a neglected tropical disease (NTD) that can lead to severe cardiac complications, including chronic Chagas cardiomyopathy. While NTDs are caused by a variety of pathogens—such as protozoa, bacteria, viruses, and helminths, Chagas disease remains underexplored, particularly regarding host immune responses.
Caroline de Souza Ferreira Pereira +2 more
wiley +1 more source
Oxidative Stress Modulation and Antileishmanial Activity of Salvinia auriculata
Ethanolic extract of Salvinia auriculata showed significant antioxidant and antileishmanial activities. Salviniside II, the major metabolite, was isolated, structurally characterized, and evaluated, but exhibited weaker antiparasitic effects when compared to the whole extract.
Augusto César Rodrigues +6 more
wiley +1 more source
Natural canine infection by Leishmania infantum and Leishmania amazonensis and their implications for disease control [PDF]
Leishmaniose é um grande problema de saúde pública global. Devido à adaptação de Leishmania a novos hospedeiros ou vetores, conhecimentos sobre o agente etiológico atual em cães é importante em áreas endêmicas.
Dolabela de Lima, Beatriz +5 more
core +4 more sources
ABSTRACT Essential oils are rich in bioactive molecules like terpenes and phenolic compounds, but have low yields, making process efficiency crucial. Enzyme‐assisted hydrodistillation is a sustainable alternative, enhancing oil release by degrading the cell wall.
Júlio César Gonçalves de Souza +7 more
wiley +1 more source
ABSTRACT Biodiversity offers a rich source of bioactive compounds for drug discovery. We isolated Aspergillus fumigatus from compost in the Atlantic Forest and found its extract active against Leishmania (Leishmania) amazonensis. Two crude extracts, I06 and I75, were selected for further study.
Juliana Cristina Pereira Calado +11 more
wiley +1 more source
SUMMARYIn South America, visceral leishmaniasis is frequently caused by Leishmania infantum and, at an unknown frequency, by Leishmania amazonensis. Therefore, mixed infections with these organisms are possible. Mixed infections might affect the clinical course, immune response, diagnosis, treatment and epidemiology of the disease. Here we describe the
Jordanna Luíza, DE Lima Celeste +8 more
openaire +2 more sources
Nueva estrategia terapéutica basada en nanotecnología contra leishmaniasis tegumentaria en Ecuador = New pharmacological strategy based in nanotechnology against cutaneous leishmaniasis in Ecuador [PDF]
Leishmaniasis is an endemic disease with wide distribution in tropical and subtropical regions around the world. It is considered that the incidence of this infection would be increased due to the progressive urbanization process which consequence is the
Loayza Villa, María Fernanda
core

