Results 51 to 60 of about 66,437 (256)

Characterization of oxidative stress in Leishmaniasis-infected or LPS-stimulated macrophages using electrochemical impedance spectroscopy [PDF]

, 2010
The physiological changes caused by external stimuli can be employed as parameters to study pathogen infection in cells and the effect of drugs. Among analytical methods, impedance is potentially useful to give insight into cellular behavior by studying ...
Coste, Agnès, Fabre, Paul-Louis, Launay, Jérôme, Nepveu, Françoise, Reybier, Karine, Ribaut, Clothilde   +5 more
core   +2 more sources

Leishmania (Leishmania) amazonensis Infection in Mice Treated With FTY720

Transplantation Proceedings, 2010
In transplantation, parasite diseases are transmitted from the donor, or appear as de novo infections, or activate from a dormant insource as a consequence of immunosuppression. Clinical findings have shown that an intact immune system is crucial to prevent recurrence of Leishmania infection.
Lopes, C. T. UNIFESP, De Paula, Daisy Maria Bentes UNIFESP, Cury, P. M., Valero-Lapchik, V. B. UNIFESP, Bueno, V. UNIFESP   +4 more
openaire   +3 more sources

Cell migration induced by Leishmania (Leishmania) amazonensis, Leishmania (Leishmania) major and Leishmania (Viannia) braziliensis into the peritoneal cavity of BALB/c mice

Journal of Venomous Animals and Toxins including Tropical Diseases, 2010
In American cutaneous leishmaniasis, the initial infection phase is characterized by recruitment of neutrophils and monocytes. The migration of these cells in response to the presence of Leishmania in the peritoneum of affected animals remains unclear ...
DT Wakimoto, KV Gaspareto, TGV Silveira, MVC Lonardoni, SMA Aristides   +4 more
doaj   +1 more source

Persistence of Leishmania antigen in C57Bl/6j inbred mice infected with Leishmania (Leishmania) amazonensis [PDF]

Revista da Associação Médica Brasileira, 1999
To develop an animal model for studying mucocutaneous leishmaniasis.The hind footpad of C57Bl/6j inbred mice was experimentally infected with 10(7) Leishmania (Leishmania) amazonensis promastigote and the skin was studied through light and electron transmission microscopy and immunohistochemistry (PAP) techniques.There were morphological evidences of ...
Vasconcellos, C., Kauffman, M.R., Sotto, M. N.   +2 more
openaire   +4 more sources

Real-time imaging of Leishmania mexicana-infected early phagosomes: a study using primary macrophages generated from green fluorescent protein-Rab5 transgenic mice [PDF]

, 2009
The small GTPase Rab5 is a key regulator of endosome/phagosome maturation and in intravesicular infections marks a phagosome stage at which decisions over pathogen replication or destruction are integrated.
Aebischer, Toni, Blackburn, Clare, Brand, Janko, Brinkmann, Volker, Hoffmann, Kirstin, Lippuner, Christoph, Paape, Daniel, Paterou, Athina, Richardson, Melville, Smith, Andrew   +9 more
core   +1 more source

Inhibition of Leishmania (Leishmania) amazonensis growth and infectivity by aureobasidin A [PDF]

Journal of Antimicrobial Chemotherapy, 2007
To study the effect of aureobasidin A, an inhibitor of inositol phosphorylceramide (IPC) synthase, on Leishmania growth and infectivity.Effects of aureobasidin A were determined for: (i) promastigote growth in axenic culture; (ii) promastigote infectivity in macrophage monolayers; (iii) development of footpad lesions in BALB/c mice; (iv ...
Ameria K, Tanaka, Valderez B, Valero, Helio K, Takahashi, Anita H, Straus   +3 more
openaire   +2 more sources

In vitro leishmanicidal effect of Yangambin and Epi-yangambin lignans isolated from Ocotea fasciculata (Nees) Mez

Frontiers in Cellular and Infection Microbiology, 2023
IntroductionYangambin and epi-yangambin are the main lignans found in Louro-de-Cheiro [Ocotea fasciculata (Nees) Mez], a tree native to the Atlantic forests of northeastern Brazil whose leaves and bark are widely used in folk medicine.
Jéssica Rebouças-Silva, Jéssica Rebouças-Silva, Gabriel Farias Santos, José Maria Barbosa Filho, Andresa A. Berretta, Franciane Marquele-Oliveira, Valéria M. Borges, Valéria M. Borges   +7 more
doaj   +1 more source

Expanding the knowledge about Leishmania species in wild mammals and dogs in the Brazilian savannah [PDF]

, 2015
Background: Wild, synanthropic and domestic mammals act as hosts and/or reservoirs of several Leishmania spp. Studies on possible reservoirs of Leishmania in different areas are fundamental to understand host-parasite interactions and develop strategies ...
AG Schijman, ALR Roque, ALR Roque, AM Jansen, Ana Gabriela Dietrich, BS Lima, CA Hoare, CJ Alho, CO Carranza-Tamayo, CR Bonvicino, DT Haydon, ES Silva, F Dantas-Torres, F Dantas-Torres, F Dantas-Torres, FM Silva, FS Oliveira, G Karbowiak, G Schönian, GA Romero, GM Oliveira, Gustavo Adolfo Sierra Romero, H Sato, I Cruz, J Alvar, JA Vexenat, JCA Carreira, JE Tolezano, JF Ribeiro, Jônatas Barbosa Cavalcante Ferreira, Júnio Donizette Mendes, LF Chaves, LM Deane, MA Sousa de, Marcelo Lima Reis, Mariana Machado Hecht, ME Santiago, MR Briones, Nadjar Nitz Silva Lociks de Araújo, NE Peterson, PF Quaresma, R Lainson, R Lainson, R Lainson, Rebecca Martins Cardoso, RG Becker, RM Breuil du, RM Humberg, Rodrigo Gurgel-Gonçalves, RP Souto, RW Ashford, SP Brandao-Filho, SP Brandao-Filho, SV Oliveira, T Silva AC da, Thaís Tâmara Castro Minuzzi Souza, TPT Freitas de, UNESCO   +57 more
core   +2 more sources

In silico predicted epitopes from the COOH-terminal extension of cysteine proteinase B inducing distinct immune responses during Leishmania (Leishmania) amazonensis experimental murine infection [PDF]

, 2011
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Molecular e Doenças Endêmicas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Molecular e Doenças Endêmicas.
Bernardo AS Pereira, Franklin S Silva, Karina M Rebello, Marcel Marín-Villa, Yara M Traub-Cseko, Thereza CB Andrade, Álvaro L Bertho, Ernesto R Caffarena, Carlos R Alves   +8 more
core   +2 more sources

Leishmania amazonensis Infection in Nude Mice.

Experimental Animals, 1999
Leishmania amazonensis is an intracellular protozoan parasite of macrophages. Cutaneous leishmaniasis in an immunocompetent host begins as papules or nodules followed by ulceration at the site of promastigote inoculation. In this study, the pathological changes of cutaneous leishmaniasis lesions in T cell deficient nude mice were examined.
M, Terabe, T, Hatabu, H, Takahashi, M, Ito, T, Onodera, Y, Matsumoto   +5 more
openaire   +3 more sources