Inhibition of growth of Leishmania mexicana mexicana by Leishmania mexicana amazonensis during "in vitro" co-cultivation Inibição do crescimento de Leishmania mexicana mexicana por Leishmania mexicana amazonensis durante o co-cultivo "in vitro" [PDF]
Memorias do Instituto Oswaldo Cruz, 1987 Inhibition of one Leishmania subspecies by exometabolites of another subspecies, a phenomenon not previously reported, is suggested by our recent observations in cell cloning experiments with Leishmania mexicana mexicana and Leishmania mexicana ...
Raquel S. Pacheco +2 more
doaj +7 more sources
Inhibitory Effects of Leishmania Mexicana infection on MHC-I Expression in Bone Marrow Derived Dendritic Cells [PDF]
Iranian Journal of Parasitology, 2022 Background: Leishmania is a parasite causing leishmaniasis with different clinical manifestations depending on the infectious species in many countries worldwide.
Hossein Rezvan +2 more
doaj +3 more sources
Real-time imaging of Leishmania mexicana-infected early phagosomes: a study using primary macrophages generated from green fluorescent protein-Rab5 transgenic mice [PDF]
, 2009 The small GTPase Rab5 is a key regulator of endosome/phagosome maturation and in intravesicular infections marks a phagosome stage at which decisions over pathogen replication or destruction are integrated.
Aebischer, Toni +9 more
core +3 more sources
Morfometria amastigotica y desarrollo de cuatro aislados de Leishmania mexicana pifanoi de Venezuela em Lutzomyia townsendi Amastigote morphometry and development of 4 isolated of Leishmania mexicana pifanoi of Venesuela in Lutzomyia townsendi [PDF]
Memorias do Instituto Oswaldo Cruz, 1982 Utilizando parámetros biométricos de la fase amastigota y el tipo de desarrollo de los parásitos en el flebótomo Lutzomyia townsendi, se han estudiado cuatro aislados de Leishmania obtenidos de pacientes con leishmaniasis cutánea difusa, comparándolos ...
J. V. Scorza, O. Delgado
doaj +2 more sources
Stage-specific proteinases ofLeishmania mexicana mexicanapromastigotes [PDF]
FEMS Microbiology Letters, 1992 Four distinct bands of cysteine proteinase activity were detected when stationary-phase populations of Leishmania mexicana mexicana were subjected to gelatin-SDS-PAGE. The highest mobility band contained at least three isoforms separable by mono Q anion exchange chromatography.
C D, Robertson, G H, Coombs
openaire +3 more sources
Unique Leishmania mexicana clones secrete populations of extracellular vesicles with unique protein profile and variable infectious capability [PDF]
Frontiers in Cellular and Infection MicrobiologyThe study of extracellular vesicles has become an incredibly important field of study, but the inherent heterogeneity of these vesicles continues to make their study challenging.
George Dong +4 more
doaj +2 more sources
Colonisation resistance in the sand fly gut: Leishmania protects Lutzomyia longipalpis from bacterial infection [PDF]
Parasites & Vectors, 2014 Background Phlebotomine sand flies transmit the haemoflagellate Leishmania, the causative agent of human leishmaniasis. The Leishmania promastigotes are confined to the gut lumen and are exposed to the gut microbiota within female sand flies.
Mauricio RV Sant’Anna +8 more
doaj +6 more sources
Catalase impairs Leishmania mexicana development and virulence. [PDF]
Virulence, 2021 Catalase is one of the most abundant enzymes on Earth. It decomposes hydrogen peroxide, thus protecting cells from dangerous reactive oxygen species. The catalase-encoding gene is conspicuously absent from the genome of most representatives of the family Trypanosomatidae.
Sádlová J +15 more
europepmc +5 more sources
Down-Regulation of TLR and JAK/STAT Pathway Genes Is Associated with Diffuse Cutaneous Leishmaniasis: A Gene Expression Analysis in NK Cells from Patients Infected with Leishmania mexicana. [PDF]
PLoS Neglected Tropical Diseases, 2016 An important NK-cell inhibition with reduced TNF-α, IFN-γ and TLR2 expression had previously been identified in patients with diffuse cutaneous leishmaniasis (DCL) infected with Leishmania mexicana.
Edith A Fernández-Figueroa +6 more
doaj +3 more sources
Functional and genetic evidence that nucleoside transport is highly conserved in Leishmania species: Implications for pyrimidine-based chemotherapy [PDF]
International Journal for Parasitology: Drugs and Drug Resistance, 2017 Leishmania pyrimidine salvage is replete with opportunities for therapeutic intervention with enzyme inhibitors or antimetabolites. Their uptake into cells depends upon specific transporters; therefore it is essential to establish whether various ...
Khalid J.H. Alzahrani +7 more
doaj +4 more sources