Triose Phosphate Isomerase Structure-Based Virtual Screening and In Vitro Biological Activity of Natural Products as Leishmania mexicana Inhibitors [PDF]
Pharmaceutics, 2023 Cutaneous leishmaniasis (CL) is a public health problem affecting more than 98 countries worldwide. No vaccine is available to prevent the disease, and available medical treatments cause serious side effects.
Luis D. González-Morales +10 more
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Glucose Transporters and Virulence in Leishmania mexicana
mSphere, 2018 Glucose transport plays important roles for in vitro growth of insect-stage promastigotes and especially for viability of intramacrophage mammalian host-stage amastigotes of Leishmania mexicana .
Xiuhong Feng +4 more
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Human Dendritic Cell Maturation Is Modulated by Leishmania mexicana through Akt Signaling Pathway [PDF]
Tropical Medicine and Infectious DiseaseDendritic cells (DC) along with macrophages are the main host cells of the intracellular parasite Leishmania. DC traverse a process of maturation, passing through an immature state with phagocytic ability to a mature one where they can modulate the ...
Jorge Rodríguez-González +2 more
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Endocytosis and Sphingolipid Scavenging in Leishmania mexicana Amastigotes [PDF]
Biochemistry Research International, 2012 Leishmania species are the causative agents of the leishmaniases, a spectrum of neglected tropical diseases. Amastigote stage parasites exist within macrophages and scavenge host factors for survival, for example, Leishmania species utilise host ...
Hayder Z. Ali +2 more
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Topical Application of Oxylipin (3<i>S</i>)-16,17-Didehydrofalcarinol in Mice Infected with <i>Leishmania mexicana</i>: A Possible Treatment for Localized Cutaneous Leishmaniasis. [PDF]
J Nat ProdCarrillo-Aké AG +8 more
europepmc +2 more sources
<i>Leishmania mexicana</i> pathogenicity requires flagellar assembly but not motility. [PDF]
VirulenceBeneke T +8 more
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Leishmania mexicana N-Acetyltransferease 10 Is Important for Polysome Formation and Cell Cycle Progression. [PDF]
Mol MicrobiolMaran SR +16 more
europepmc +3 more sources
Synthesis of Antiprotozoal 2-(4-Alkyloxyphenyl)-Imidazolines and Imidazoles and Their Evaluation on Leishmania mexicana and Trypanosoma cruzi. [PDF]
Int J Mol SciTorres-Jaramillo J +6 more
europepmc +3 more sources
Revista da Sociedade Brasileira de Medicina Tropical, 1985 Three isolates of Leishmania were recovered from five of 27 specimens of the rodent Proechimys iheringi denigratus Moojen captured near Três Braços in the Atlantic Forest region of Bahia, Brazil.
Air C. Barretto +7 more
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The DNA polymerases ofLeishmania mexicana [PDF]
FEMS Microbiology Letters, 1992 Two previously isolated DNA polymerases from the parasitic protozoan Leishmania mexicana were further characterized by exposure to inhibitors of mammalian DNA polymerases. DNA polymerase A, a high molecular mass enzyme, and DNA polymerase B, a beta-like DNA polymerase were compared to each other and to their mammalian counterparts regarding pH optimum,
L L, Nolan, J H, Rivera
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