Results 11 to 20 of about 13,441 (240)

Leishmania manipulation of sand fly feeding behavior results in enhanced transmission. [PDF]

, 2007
In nature the prevalence of Leishmania infection in whole sand fly populations can be very low (
Bates, Paul A, Rogers, Matthew E
core   +7 more sources

Changes to cholesterol trafficking in macrophages by Leishmania parasites infection [PDF]

, 2017
Leishmania spp. are protozoan parasites that are transmitted by sandfly vectors during blood sucking to vertebrate hosts and cause a spectrum of diseases called leishmaniases.
Anderson, Andrade-Neto, Antoine, Bansal, Berman, Blanchette-Mackie, Burack, Carstea, Carvalho, Chakraborty, Chattopadhyay, Collins, Coombs, Coppens, De Cicco, Desvergne, Duclos, Edwards, Ehrenman, Fernandes, Ghosh, Ghosh, Ghosh, Ginger, Ginger, Goldstein, Groener, Hamid, Hart, Ikonen, Infante, Johndrow, Kima, Kima, Kok, Kwon, Lal, Lecoeur, Lippuner, Livak, Majumder, Maxfield, McIntosh, Misslitz, Naureckiene, Neufeld, Osorio y Fortea, Ovalle-Bracho, Paape, Paape, Pereira, Portugal, Pucadyil, Rabhi, Redgrave, Roberts, Rosenzweig, Rub, Russell, Saunders, Sen, Shamshiev, Soares, Sorensen, Tetley, Tewary, Tontonoz, Weinheber   +67 more
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Real-time imaging of Leishmania mexicana-infected early phagosomes: a study using primary macrophages generated from green fluorescent protein-Rab5 transgenic mice [PDF]

, 2009
The small GTPase Rab5 is a key regulator of endosome/phagosome maturation and in intravesicular infections marks a phagosome stage at which decisions over pathogen replication or destruction are integrated.
Aebischer, Toni, Blackburn, Clare, Brand, Janko, Brinkmann, Volker, Hoffmann, Kirstin, Lippuner, Christoph, Paape, Daniel, Paterou, Athina, Richardson, Melville, Smith, Andrew   +9 more
core   +1 more source

Functional and genetic evidence that nucleoside transport is highly conserved in Leishmania species: Implications for pyrimidine-based chemotherapy [PDF]

, 2017
Leishmania pyrimidine salvage is replete with opportunities for therapeutic intervention with enzyme inhibitors or antimetabolites. Their uptake into cells depends upon specific transporters; therefore it is essential to establish whether various ...
Ali, Juma A.M., Alzahrani, Khalid J.H., Barrett, Michael P., Creek, Darren J., De Koning, Harry P., Eze, Anthonius A., Looi, Wan Limm, Tagoe, Daniel N.A.   +7 more
core   +2 more sources

Detection and identification of Leishmania species within naturally infected sand flies in the Andean areas of Ecuador by a polymerase chain reaction [PDF]

, 2005
The surveillance of prevalent Leishmania and sand fly species in endemic areas is important for prediction of the risk and expansion of leishmaniasis. In this study, we developed a polymerase chain reaction (PCR)-based method for detection of Leishmania ...
Barroso, Paola Andrea, Calvopina, Manuel, Gomez, Eduardo, Hashiguchi, Yoshihisa, Iwata, Hiroyuki, Katakura, Ken, Kato, Hirotomo, Korenaga, Masataka, Marco, Jorge Diego, Mimori, Tatsuyuki, Nonaka, Shigeo, Uezato, Hiroshi   +11 more
core   +1 more source

Genome-wide mapping reveals single-origin chromosome replication in Leishmania, a eukaryotic microbe [PDF]

, 2015
Background DNA replication initiates on defined genome sites, termed origins. Origin usage appears to follow common rules in the eukaryotic organisms examined to date: all chromosomes are replicated from multiple origins, which display variations in ...
Campbell, Samantha J., Dickens, Nicholas J., Marques, Catarina A., McCulloch, Richard, Paape, Daniel   +4 more
core   +2 more sources

Leishmania isoenzyme polymorphisms in Ecuador: Relationships with geographic distribution and clinical presentation [PDF]

, 2006
Background: Determinants of the clinical presentation of the leishmaniases are poorly understood but Leishmania species and strain differences are important.
A Schriefer, AL Bañuls, B Rotureau, CM Lucas, D Evans, D McMahon-Pratt, E Cupolillo, E Cupolillo, E Handman, E Handman, EA Gomez, Eduardo A Gomez, F Pratlong, H Yamasaki, Hiroshi Uezato, Hirotomo Kato, J Convit, JB Alexander, JC Dujardin, JC Dujardin, JD Marco, JJ Shaw, Jorge D Marco, M Calvopina, M Calvopina, M Chico, M Furuya, Manuel Calvopina, Masataka Korenaga, NE Reiner, NG Saravia, P Jaccard, Paola A Barroso, Philip J Cooper, RD Kreutzer, Rodrigo X Armijos, RX Armijos, RX Armijos, S Kumar, S Nonaka, SB Abderrazak, Shigeo Nonaka, T Mimori, Tatsuyuki Mimori, World Health Organization, Y Hashiguchi, Y Hashiguchi, Y Hashiguchi, Yoshihisa Hashiguchi   +48 more
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Visceral leishmaniasis patients display altered composition and maturity of neutrophils as well as impaired neutrophil effector functions [PDF]

, 2016
Immunologically, active visceral leishmaniasis (VL) is characterised by profound immunosuppression, severe systemic inflammatory responses and an impaired capacity to control parasite replication.
Adem, E, Cruz Cervera, E, Diro, E, Getahun, M, Hailu, A, Kropf, P, Lemma, M, Melkamu, R, Mengesha, B, Mesfin, G, Modolell, M, Muller, I, Munder, M, Skhedy, Z, Tajebe, F, Takele, Y, Van der Auwera, G, Yardley, V, Yeshanew, A, Yizengaw, E   +19 more
core   +6 more sources

Intra- and interspecific polymorphisms ofLeishmania donovani andL. tropica minicircle DNA [PDF]

, 1994
A pair of degenerate polymerase chain reaction (PCR) primers (LEI-1, TCG GAT CC[C,T] [G,C]TG GGT AGG GGC GT; LEI-2, ACG GAT CC[G,C] [G,C][A,C]C TAT [A,T]TT ACA CC) defining a 0.15-kb segment ofLeishmania minicircle DNA was constructed.
AJ Magill, DC Barker, DF Smith, DG Higgins, F Sanger, GZ Kidane, H. Rinder, JM Blackwell, K Stuart, MHL Bruijn de, P. Dobner, R Sommer, RD Kreutzer, S Lee, T Laskay, T. L�scher, WO Rogers   +16 more
core   +1 more source

Transient superdiffusion and long-range correlations in the motility patterns of trypanosomatid flagellate protozoa [PDF]

PLoS ONE 11(3): e0152092 (2016), 2016
We report on a diffusive analysis of the motion of flagellate protozoa species. These parasites are the etiological agents of neglected tropical diseases: leishmaniasis caused by Leishmania amazonensis and Leishmania braziliensis, African sleeping sickness caused by Trypanosoma brucei, and Chagas disease caused by Trypanosoma cruzi.
arxiv   +1 more source