Results 41 to 50 of about 8,190 (198)

World Association for Veterinary Dermatology Consensus Statement for Diagnosis, and Evidence‐Based Clinical Practice Guidelines for Treatment and Prevention of Canine Leishmaniosis

Veterinary Dermatology, Volume 36, Issue 6, Page 723-787, December 2025.
Hyperkeratosis of (a) the footpads and (b) the nasal planum. ABSTRACT Background Canine leishmaniosis (CanL) due to Leishmania infantum remains common, and veterinarians do not always follow scientifically sound approaches for diagnosis, treatment and prevention. Objectives To provide consensus guidelines for diagnosis and evidence‐based guidelines for
Manolis N. Saridomichelakis, Gad Baneth, Silvia Colombo, Filipe Dantas‐Torres, Lluís Ferrer, Alessandra Fondati, Guadalupe Miró, Laura Ordeix, Domenico Otranto, Chiara Noli   +9 more
wiley   +1 more source

Geographic Distribution of Leishmania Species in Ecuador Based on the Cytochrome B Gene Sequence Analysis. [PDF]

PLoS Neglected Tropical Diseases, 2016
A countrywide epidemiological study was performed to elucidate the current geographic distribution of causative species of cutaneous leishmaniasis (CL) in Ecuador by using FTA card-spotted samples and smear slides as DNA sources.
Hirotomo Kato, Eduardo A Gomez, Luiggi Martini-Robles, Jenny Muzzio, Lenin Velez, Manuel Calvopiña, Daniel Romero-Alvarez, Tatsuyuki Mimori, Hiroshi Uezato, Yoshihisa Hashiguchi   +9 more
doaj   +1 more source

Effects of TcFLA‐1BP and TcGP72 Deletion on the Infectivity and Survival of Trypanosoma cruzi in Cell Cultures

Cell Biology International, Volume 49, Issue 11, Page 1395-1410, November 2025.
ABSTRACT Chagas disease, caused by the protozoan Trypanosoma cruzi, is a neglected tropical disease with limited treatment options and no available vaccine. Understanding the role of proteins in the parasite's biological cycle is critical for advancing vaccine development and optimizing therapies.
Normanda Souza‐Melo, Giovanna Henriques de Souza, Wanderley de Souza   +2 more
wiley   +1 more source

Presencia de nectomonadas metaciclicas de L. pifanoi en la hipofaringe de Lutzomyia youngi y la ingestion de azúcares Metacyclical forms of L. pifanoi in the hypopharynx of Lutzomyia youngi and their sugar consumption

Revista de Saúde Pública, 1996
Se evidencia la presencia de promastigotos metacíclicos de Leishmania pifanoi en el conducto hipofaríngeo de Lutzomyia youngi infectados experimentalmente por ingurgitación sobre lesiones tarsales de hámsteres.
Elina Rojas, José V. Scorza
doaj   +1 more source

Structure of Leishmania mexicana lipophosphoglycan.

Journal of Biological Chemistry, 1992
Lipophosphoglycan (LPG) was isolated from the culture supernatant of Leishmania mexicana promastigotes and its structure elucidated by a combination of 1H NMR, fast atom bombardment mass spectrometry, methylation analysis, and chemical and enzymatic modifications. It consists of the repeating phosphorylated oligosaccharides PO4-6Gal beta 1-4Man alpha 1-
Ilg, Thomas, Etges, Robert, Overath, Peter, McConville, Malcolm J., Thomas-Oates, Jane, Thomas, Jerry, Homans, Steven W., Ferguson, Michael A.   +7 more
openaire   +2 more sources

Complete Resolution of Cutaneous Leishmaniasis With a Novel Topical Combination Therapy: A Case Series

Clinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT Cutaneous leishmaniasis (CL) remains a therapeutic challenge in endemic regions, with 600,000–1 million new cases annually facing limited treatment options. We present a case series evaluating an innovative topical combination therapy for acute‐phase CL in Shiraz, Iran.
Hoda Haghshenas, Aref Ghanaatpisheh, Mohammad Darayesh, Elaheh Entezar Almahdi   +3 more
wiley   +1 more source

Ecology of phlebotomine sandflies and putative reservoir hosts of leishmaniasis in a border area in Northeastern Mexico: implications for the risk of transmission of Leishmania mexicana in Mexico and the USA

Parasite, 2017
Leishmaniases are a group of important diseases transmitted to humans through the bite of sandfly vectors. Several forms of leishmaniases are endemic in Mexico and especially in the Southeast region.
Rodríguez-Rojas Jorge J., Rodríguez-Moreno Ángel, Berzunza-Cruz Miriam, Gutiérrez-Granados Gabriel, Becker Ingeborg, Sánchez-Cordero Victor, Stephens Christopher R., Fernández-Salas Ildefonso, Rebollar-Téllez Eduardo A.   +8 more
doaj   +1 more source

Production of the Antimicrobial Roseoflavin With Genetically Engineered Corynebacterium glutamicum

Microbial Biotechnology, Volume 18, Issue 10, October 2025.
Corynebacterium glutamicum was genetically engineered for the production of the riboflavin analog roseoflavin, while minimising its antimicrobial effects. To this end, the genetic machinery from the natural roseoflavin producer Streptomyces davaonensis was evaluated in a riboflavin‐producing C. glutamicum strain.
Luciana Fernandes Brito, Ane Bræin Aas, Rosa Jodalen Rudberg, Trygve Brautaset, Fernando Pérez‐García   +4 more
wiley   +1 more source

In Situ Evaluation of Macrophage Populations and Inflammasome Components in Cutaneous and Mucocutaneous Leishmaniasis

Parasite Immunology, Volume 47, Issue 9, September 2025.
ABSTRACT American tegumentary leishmaniasis (ATL) affects the skin and mucous membranes, with a spectrum shaped by Th1/Th2 responses. This study investigated inflammasome activation in correlation with macrophage subpopulations, tissue parasitism, and histological changes in cutaneous and mucocutaneous leishmaniasis. We assessed inflammasome activation,
Caroline de Heleno Chagas de Carvalho, Gabriela Venicia Araujo Flores, Carmen Maria Sandoval Pacheco, Vania Lucia da Ribeiro da Matta, Carolina de Esteves de Morais, Ricardo Romiti, Walter Belda Júnior, Márcia Dalastra Laurenti   +7 more
wiley   +1 more source

Colonisation resistance in the sand fly gut: Leishmania protects Lutzomyia longipalpis from bacterial infection

Parasites & Vectors, 2014
Background Phlebotomine sand flies transmit the haemoflagellate Leishmania, the causative agent of human leishmaniasis. The Leishmania promastigotes are confined to the gut lumen and are exposed to the gut microbiota within female sand flies.
Mauricio RV Sant’Anna, Hector Diaz-Albiter, Kelsilândia Aguiar-Martins, Waleed S Al Salem, Reginaldo R Cavalcante, Viv M Dillon, Paul A Bates, Fernando A Genta, Rod J Dillon   +8 more
doaj   +1 more source