Results 41 to 50 of about 15,700 (261)

A combination DNA vaccine encoding nucleoside hydrolase 36 and glycoproteine 63 protects female but not male hamsters against Leishmania mexicana

open access: yesParasite, 2009
Leishmaniasis is a group of diseases caused by protozoan parasites of the Leishmania genus. Previous studies have shown that a DNA vaccine encoding Leishmania donovani antigen nucleoside hydrolase 36 and L. mexicana glycoprotein 63 is protective in mice.
Chalé-balboa W.G.   +4 more
doaj   +1 more source

Leishmania (Leishmania) mexicana en el corregimiento de San Matías, municipio de Gómez Plata, Antioquia, Colombia

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2006
Introducción. La leishmaniaisis es una enfermedad encontrada en focos naturales de infección donde están presentes insectos vectores y mamíferos reservorios deLeishmania. Objetivo.
Diana Sierra   +5 more
doaj   +1 more source

Systematic functional analysis of Leishmania protein kinases identifies regulators of differentiation or survival

open access: yesNature Communications, 2021
Protein kinases are fundamental in cellular signalling required for Leishmania survival throughout the life cycle. Here, Baker and Catta-Preta et al. report on a kinome-wide functional study in Leishmania mexicana to define protein kinases with roles in ...
N. Baker   +17 more
doaj   +1 more source

De-novo design of complementary (antisense) peptide mini-receptor inhibitor of interleukin 18 (IL-18).

open access: yes, 2004
Complementary (antisense) peptide mini-receptor inhibitors are complementary peptides designed to be receptor-surrogates that act by binding to selected surface features of biologically important proteins thereby inhibiting protein-cognate receptor ...
Bhakoo, Ashish   +4 more
core   +1 more source

Anti-Trypanosoma cruzi action of a new benzofuran derivative based on amiodarone structure [PDF]

open access: yes, 2018
Chagas disease is a neglected tropical affection caused by the protozoan parasite Trypanosoma cruzi. There is no current effective treatment since the only two available drugs have a limited efficacy and produce side effects.
Benaim, Gustavo   +4 more
core   +1 more source

Pathos: a web facility that uses metabolic maps to display experimental changes in metabolites identified by mass spectrometry [PDF]

open access: yes, 2011
This work describes a freely available web-based facility which can be used to analyse raw or processed mass spectrometric data from metabolomics experiments and display the metabolites identified – and changes in their experimental abundance – in the ...
Barrett, M.P.   +3 more
core   +2 more sources

Activity of Hydroxyurea against Leishmania mexicana [PDF]

open access: yesAntimicrobial Agents and Chemotherapy, 2008
ABSTRACT Leishmania mexicana is a protozoan parasite that causes a disease in humans with frequent relapses after treatment. It is also highly resistant to the currently available drugs. For this reason, there is an urgent need for more effective antileishmanial drugs.
Hugo, Martinez-Rojano   +3 more
openaire   +2 more sources

Leishmania (L.) mexicana infected bats in Mexico: novel potential reservoirs.

open access: yesPLoS Neglected Tropical Diseases, 2015
Leishmania (Leishmania) mexicana causes cutaneous leishmaniasis, an endemic zoonosis affecting a growing number of patients in the southeastern states of Mexico.
Miriam Berzunza-Cruz   +12 more
doaj   +1 more source

Leishmania (Leishmania) mexicana Infection in Wild Rodents from an Emergent Focus of Cutaneous Leishmaniasis in Yucatan, Mexico

open access: yesJournal of Tropical Medicine, 2022
In 2015, emergent cases of localized cutaneous leishmaniasis (LCL) were reported in Tinum, Yucatan, Mexico. As part of an eco-epidemiological study to characterize the elements that trigger Leishmania infection in that area, we conducted a field study to
Erika I. Sosa-Bibiano   +7 more
doaj   +1 more source

Leishmaniasis: new approaches to disease control. [PDF]

open access: yes, 2003
The leishmaniases afflict the world's poorest populations. Among the two million new cases each year in the 88 countries where the disease is endemic (fig 1), it is estimated that 80% earn less than $2 a day.
Croft, Simon L   +3 more
core   +2 more sources

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