Results 151 to 160 of about 319,296 (404)
Molecular Metabolism, 2018 Objective: The inability of leptin to suppress food intake in diet-induced obesity, sometimes referred to as leptin resistance, is associated with several distinct pathological hallmarks.
Maximilian Kleinert +5 more
doaj
Alterations in Lipids and Adipocyte Hormones in Female-to-Male Transsexuals [PDF]
, 2010 Testosterone therapy in men and women results in decreased high-density lipoprotein cholesterol (HDL) and increased low-density lipoprotein cholesterol (LDL).
Basra, Sukhdeep S. +3 more
core +5 more sources
Exploring the Molecular Pathways Underlying the Anti‐Diabetic Effects of Millets
Food Safety and Health, EarlyView.Millet consumption may modulate gluconeogenesis and glycolysis, enhance glucose transporter activity, increase leptin levels, inhibit the NF‐κB pathway, and mitigate oxidative and nitrosative stress. ABSTRACT Diabetes mellitus (DM) is a metabolic disorder characterized by hyperglycemic conditions resulting from inadequate insulin production or ...
Akash Kumar +5 more
wiley +1 more source
Journal of Lipid Research, 2006 The mechanisms of the increased serum leptin in response to feeding are poorly understood. Therefore, we used metabolic labeling to directly assess leptin biosynthesis, secretion, and turnover in adipose tissue from 14 h-starved compared with fed 12–14 ...
Mi-Jeong Lee, Susan K. Fried
doaj
Cellular Physiology and Biochemistry, 2017 Background/Aims: Leptin is a hormone expressed by adipose tissue that regulates body energy homeostasis and weight loss by activating leptin receptors in the hypothalamus. Leptin receptors are also expressed in astrocytes.
Hyunju Park +4 more
doaj +1 more source
A Leptin-regulated Circuit Controls Glucose Mobilization During Noxious Stimuli [PDF]
, 2017 Adipocytes secrete the hormone leptin to signal the sufficiency of energy stores. Reductions in circulating leptin concentrations reflect a negative energy balance, which augments sympathetic nervous system (SNS) activation in response to metabolically ...
Allison, Margaret B. +15 more
core +1 more source
Analysis of circadian pattern reveals tissue-specific alternative transcription in leptin signaling pathway [PDF]
, 2007 *Background* It has been previously reported that most mammalian genes display a circadian oscillation in their baseline expression. Consequently, the phase and amplitude of each component of a signal transduction cascade has downstream ...
A Savitzky +17 more
core +3 more sources
Withaferin A is a Leptin Sensitizer with Strong Anti-Diabetic Properties in Mice
Nature Network Boston, 2016 The increasing global prevalence of obesity and its associated disorders points to an urgent need for the development of novel and effective therapeutic strategies that induce healthy weight loss.
Jaemin Lee +7 more
semanticscholar +1 more source
The Response of Serum Cortisol and Leptin Levels to Academic Stress [PDF]
, 2009 Background: Medical students are subjected to various types of stress during the academic course and they react differently. This study is an attempt to establish a relationship between the coping abilities, serum cortisol and leptin levels in response ...
Dayananda, G +5 more
core +1 more source
Biology Open, 2016 Leptin is an essential hormone for the regulation of energy metabolism and food intake in vertebrate animals. To better understand the physiological roles of leptin in nutrient regulation in paternal ovoviviparous fish (family Syngnathidae), the present ...
Huixian Zhang +4 more
doaj +1 more source