STAT3 phosphorylation in central leptin resistance
Nutrition & Metabolism, 2021 Mechanism exploitation of energy homeostasis is urgently required because of the worldwide prevailing of obesity-related metabolic disorders in human being.
Huimin Liu +3 more
doaj +1 more source
Identification of a non-mammalian leptin-like gene:characterization and expression in the tiger salamander (Ambystoma tigrinum) [PDF]
, 2006 Leptin is well established as a multifunctional cytokine in mammals. However, little is known about the evolution of the leptin gene in other vertebrates. A recently published set of ESTs from the tiger salamander (Ambystoma tigrinum) contains a sequence
Boswell, Timothy +5 more
core +1 more source
Aberrant miR-874-3p/leptin/EGFR/c-Myc signaling contributes to nasopharyngeal carcinoma pathogenesis
Journal of Experimental & Clinical Cancer Research, 2022 Background Leptin is important in physiological and pathological functions in various cancers, however, the significance and mechanisms of leptin in nasopharyngeal carcinoma remain ambiguous.
Sheng-Dean Luo +7 more
doaj +1 more source
Influence of leptin on arterial distensibility - A novel link between obesity and cardiovascular disease? [PDF]
, 2002 Background-The mechanisms by which obesity increases the risk of atherosclerotic cardiovascular disease (CVD) are poorly understood. In experimental models, leptin, a hormone produced by adipose tissue, has been shown adversely to affect vascular health.
Cole, TJ +7 more
core +1 more source
Association of the leptin receptor Q223R (rs1137101) polymorphism with obesity measures in Sri Lankans [PDF]
, 2020 OBJECTIVE: The role of genetic factors in the development of obesity is largely unreported in Sri Lankans. The Q223R (rs1137101) single nucleotide polymorphism (SNP) of the leptin receptor (LEPR) gene has been associated with obesity measures in various ...
Dalton, C.F. +3 more
core +1 more source
A theory that predicts behaviors of disordered cytoskeletal networks
Molecular Systems Biology, 2017 Morphogenesis in animal tissues is largely driven by actomyosin networks, through tensions generated by an active contractile process. Although the network components and their properties are known, and networks can be reconstituted in vitro, the ...
Julio M Belmonte +2 more
doaj +1 more source
Molecular Metabolism, 2018 Objective: The inability of leptin to suppress food intake in diet-induced obesity, sometimes referred to as leptin resistance, is associated with several distinct pathological hallmarks.
Maximilian Kleinert +5 more
doaj +1 more source
Adiponectin, in contrast to leptin, is not associated with body mass index, waist circumference and HOMA-IR in subjects of a west-African population [PDF]
, 2018 Factors associated with plasma levels of adiponectin and leptin were studied in adult subjects without diabetes from Cotonou in Benin (West‐Africa). Seventy (70) men and 45 women were included in the study.
Adehan, Grace +7 more
core +1 more source
Current Immunology Reviews, 2008 The past few years of research on leptin have provided important information on the link between metabolism and immune homeostasis. Adipocytes influence not only the endocrine system but also the immune response through several cytokine-like mediators known as adipokines, which include leptin.
Iikuni N +4 more
openaire +5 more sources
High plasma leptin levels confer increased risk of atherosclerosis in women with systemic lupus erythematosus, and are associated with inflammatory oxidised lipids. [PDF]
, 2011 BackgroundPatients with systemic lupus erythematosus (SLE) are at increased risk of atherosclerosis, even after accounting for traditional risk factors.
Charles-Schoeman, Christina +14 more
core +2 more sources