Results 121 to 130 of about 72,689 (297)

Homocysteine causes neuronal leptin resistance and endoplasmic reticulum stress. [PDF]

PLoS One, 2022
Preninka AI, Kuriya K, Yazawa K, Yoshii M, Yanase Y, Jockers R, Dam J, Hosoi T, Ozawa K.   +8 more
europepmc   +1 more source

Effect of interdisciplinary obesity care on metabolic markers and body weight in people with type 2 diabetes in a rural setting: A randomised controlled trial

Clinical Obesity, Volume 15, Issue 2, April 2025.
Summary Management of type 2 diabetes includes medications that can unintentionally increase obesity and insulin resistance. This unblinded, single‐centre, randomised controlled trial focused on rural Australian adults with type 2 diabetes (aged 18–75 and body mass index [BMI] >30 kg/m2), measuring the effectiveness of a tailored interdisciplinary ...
Giuliana O. Murfet, Iain K. Robertson, Sharon P. Luccisano, Michelle L. Kilpatrick   +3 more
wiley   +1 more source

CRF1 and ACTH inhibitors are a promising approach to treat obesity and leptin and insulin resistance

Frontiers in Endocrinology
Evidence synthesisObesity is a state of subtle hypercortisolism accompanied by leptin and insulin resistance. Serum total cortisol concentration is normal or slightly subnormal in obese subjects. However, they have high cortisol production rates. Reduced
Patricio H. Contreras, Henrik Falhammar, Henrik Falhammar   +2 more
doaj   +1 more source

Elevated Hypothalamic TCPTP in Obesity Contributes to Cellular Leptin Resistance. [PDF]

Cell Metab, 2022
Loh K, Fukushima A, Zhang X, Galic S, Briggs D, Enriori PJ, Simonds S, Wiede F, Reichenbach A, Hauser C, Sims NA, Bence KK, Zhang S, Zhang ZY, Kahn BB, Neel BG, Andrews ZB, Cowley MA, Tiganis T.   +18 more
europepmc   +1 more source

SERUM LEPTIN AS A MARKER FOR INSULIN RESISTANCE IN NON-DIABETIC YOUNG ARAB FEMALES IN UNITED ARAB EMIRATES

, 2008
Veena Raigangar, Haydar Abbas Hasan, Abdul Ridha Abdullah   +2 more
openalex   +1 more source

Leptin Resistance

Journal of the American College of Cardiology, 2008
Martin, Seth S., Qasim, Atif, Reilly, Muredach P.   +2 more
openaire   +1 more source

Glucocorticoids and HPA axis regulation in the stress–obesity connection: A comprehensive overview of biological, physiological and behavioural dimensions

Clinical Obesity, Volume 15, Issue 2, April 2025.
Summary Chronic stress, characterized by increased long‐term exposure to the glucocorticoid hormone cortisol, is increasingly linked to obesity development. Still, various knowledge gaps persist, including on underlying pathophysiological mechanisms. The aim of the current review is to provide the latest insights on the connection between stress and ...
Robin Lengton, Myrte Schoenmakers, Brenda W. J. H. Penninx, Mariëtte R. Boon, Elisabeth F. C. van Rossum   +4 more
wiley   +1 more source

Sulforaphane reduces obesity by reversing leptin resistance. [PDF]

Elife, 2022
Çakır I, Lining Pan P, Hadley CK, El-Gamal A, Fadel A, Elsayegh D, Mohamed O, Rizk NM, Ghamari-Langroudi M.   +8 more
europepmc   +1 more source

Complex relationship between sex hormones, insulin resistance and leptin in men with and without prostatic disease

, 2015
Halina Grosman, Bibiana Fabre, Miguel López, Carlos H. Scorticati, Maximiliano López Silva, Viviana Mesch, Osvaldo Mazza, Gabriela Berg   +7 more
openalex   +2 more sources

Precision nutrition in weight loss and neuroendocrine control of people with obesity: The study protocol of a factorial randomised controlled trial (GenON Programme)

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Precision nutrition, guided by genetic testing, has emerged as a promising approach for managing obesity. However, robust clinical trials testing its effectiveness in real‐world dietary interventions remain scarce. The GenOn Programme aims to evaluate whether tailoring nutritional care based on genetic risk for obesity enhances weight ...
Karla P. Balbino, Ana Claudia P. Kravchychyn, Flávia G. Cândido, Mariana de Moura e Dias, Tiago Antônio de O. Mendes, Leandro Licursi de Oliveira, Luiza Carla V. Castro, Josefina Bressan, Ana Laura de la Garza, Fermín I. Milagro, María A. Zulet, Helen Hermana M. Hermsdorff   +11 more
wiley   +1 more source