Results 111 to 120 of about 2,304,681 (286)
Correlation Analysis of Body Weight with Insulin Resistance and Leptin Levels in Farm Workers
Journal of Agromedicine and Medical Sciences (AMS)Insulin resistance is a pathological condition resulting from impaired insulin response which causes increased insulin production as a form of compensation from pancreatic beta cells. A stable body weight can prevent insulin resistance and excessive body
Naurah Nazihah Azzalina +2 more
doaj +1 more source
New pharmacological perspectives for the leptin receptor in the treatment of obesity
Frontiers in Endocrinology, 2014 After its discovery in 1994, leptin became the great hope as an anti-obesity treatment based on its ability to reduce food intake and increase energy expenditure.
Clara eRoujeau +2 more
doaj +1 more source
Food Chemistry International, EarlyView.The study demonstrates how functional foods, medicinal plants, phytochemicals, bioactive compounds and essential nutrients combat metabolic diseases. It highlights their mechanisms, including antioxidant, anti‐inflammatory, insulin‐sensitising, lipid‐regulating, gut microbiota‐modulating and mitochondrial‐enhancing effects, leading to improved ...
Chinaza Godswill Awuchi +2 more
wiley +1 more source
Leptin resistance in obesity: An epigenetic landscape
Life Sciences, 2015 Leptin is an adipocyte-secreted hormone that inhibits food intake and stimulates energy expenditure through interactions with neuronal pathways in the brain, particularly pathways involving the hypothalamus. Intact functioning of the leptin route is required for body weight and energy homeostasis.
Casanueva Freijo, Felipe +5 more
openaire +3 more sources
Association of Leptin With Obesity and Insulin Resistance
Cureus, 2020 Introduction Leptin, a hormone released by the body to regulate energy balance by inhibiting hunger, decreases fat storage in adipocytes. Leptin is thought to play some role in obesity and insulin resistance. In this study, our aim is to see the association of leptin with obesity and insulin resistance.
Kumar, Ratan +8 more
openaire +2 more sources
Food Safety and Health, EarlyView.Circadian rhythm disruption impairs metabolic regulation, appetite control, and vascular function, promoting obesity and cardiovascular diseases. Evidence highlights a bidirectional relationship where metabolic disorders further disturb circadian timing.
Ghizal Fatima +4 more
wiley +1 more source
Obesity as a Risk Factor for Alzheimer’s Disease: Implication of Leptin and Glutamate
Frontiers in Neuroscience, 2019 Obesity is known to induce leptin and insulin resistance. Leptin is a peptide hormone synthesized in adipose tissue that mainly regulates food intake.
Ana Lloret +4 more
doaj +1 more source
The Role of Dietary Components in Leptin Resistance [PDF]
Advances in Nutrition, 2012 Leptin resistance has been defined as reduced or absent responsiveness to the feeding and body weight inhibitory effects of the hormone in obese individuals compared with normal (lean) controls. Classically, leptin resistance has been associated with increased body fat and circulating leptin levels, and the effect is thought to contribute to the ...
openaire +2 more sources
Mechanisms underlying leptininduced cardioprotection [PDF]
, 2010 BACKGROUND: The tissue damage resulting from myocardial ischaemia/reperfusion (I/R) leads to a large proportion of the deaths in the developed world.
Dixon, R.A.
core
Open Medicine, 2014 Cardiovascular risk of prediabetes is still subject to controversies. We analyzed the associations between insulin resistance, adipokines and incipient atherosclerosis estimated by intima-media thickness (IMT) in a cross-sectional study on 122 ...
Mihai Bogdan Mircea +3 more
doaj +1 more source