Results 121 to 130 of about 134,529 (291)

Evidence map and gap analysis of metabolic change in pediatric growth hormone deficiency treated with growth hormone

open access: yesPediatric Investigation, EarlyView.
This evidence map of 63 studies (n = 6158) showed growth hormone therapy in children with growth hormone deficiency has neutral glucose effects, mixed lipid outcomes, potential benefits for bone mineral density, bone mineral content, and parathyroid hormone, but generally no impact on thyroid function, body composition, or body mass index.
Wei Wu   +6 more
wiley   +1 more source

Effects of oral, smoked, and vaporized cannabis on endocrine pathways related to appetite and metabolism: a randomized, double-blind, placebo-controlled, human laboratory study. [PDF]

open access: yes, 2020
As perspectives on cannabis continue to shift, understanding the physiological and behavioral effects of cannabis use is of paramount importance. Previous data suggest that cannabis use influences food intake, appetite, and metabolism, yet human research
Abulseoud, Osama A   +6 more
core   +1 more source

Bile acid metabolism and sleep: Mechanistic interplay and clinical implications of the gut–liver–brain axis

open access: yesSleep Research, EarlyView.
Abstract The bidirectional interplay between sleep and metabolic homeostasis is fundamental to physiological health. While the roles of glucose and lipid metabolism in sleep regulation have been extensively characterized, bile acids (BAs), which are traditionally viewed as digestive surfactants, are emerging as critical metabolic messengers with ...
Yu Jiang   +4 more
wiley   +1 more source

Insulin resistance and adipokine levels correlate with early atherosclerosis – a study in prediabetic patients

open access: yesOpen Medicine, 2014
Cardiovascular risk of prediabetes is still subject to controversies. We analyzed the associations between insulin resistance, adipokines and incipient atherosclerosis estimated by intima-media thickness (IMT) in a cross-sectional study on 122 ...
Mihai Bogdan Mircea   +3 more
doaj   +1 more source

PFOA Exposure Elicits Quantitative Lipidomic Changes in the Pancreas in a Mouse Model of Pancreatic Cancer

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Pancreatic cancer is the fourth leading cause of cancer deaths in the US and predicted to rise to second by 2030. Several risk factors have been identified as potential contributors to pancreatic cancer development including lifestyle factors and long‐term exposure to occupational and environmental carcinogens.
Barbara A. Hocevar, Lisa M. Kamendulis
wiley   +1 more source

Comparison of the effects of endurance, resistance and concurrent training on insulin resistance and adiponectin-leptin ratio in diabetic rat

open access: yesThe Journal of Qazvin University of Medical Sciences, 2017
Background: The obesity-related hormones leptin and adiponectin are independently and oppositely associated with insulin resistance. Objective: The aim of the present study was to investigate the effect of endurance, resistance and concurrent training ...
A. Saremi
doaj  

Leptin induces altered differentiation of keratinocytes by inducing insulin resistance: implications for metabolic syndrome-induced resistance of psoriatic therapy

open access: yesJournal of Dermatological Treatment
Background: Psoriatic patients tend to develop metabolic syndrome (MS). MS accelerates psoriasis, but the exact molecular mechanisms are poorly understood.Objectives: We aim to investigate the impact of leptin on keratinocyte insulin sensitivity and ...
Rui Wang   +7 more
doaj   +1 more source

Retinal imaging in gestational diabetes mellitus: systematic review

open access: yesUltrasound in Obstetrics &Gynecology, EarlyView.
ABSTRACT Objective To examine the differences in retinal structure and vasculature between women with gestational diabetes mellitus (GDM) and normoglycemic pregnant controls. Methods This was a systematic review of the available literature on retinal assessment in pregnancies with GDM compared with non‐GDM controls, conducted in PubMed, EMBASE via Ovid,
D. Kitmiridou   +3 more
wiley   +1 more source

CNS Control of Glucose Metabolism: Response to Environmental Challenges [PDF]

open access: yes, 2013
Over the last 15 years, considerable work has accumulated to support the role of the CNS in regulating postprandial glucose levels. As discussed in the first section of this review, the CNS receives and integrates information from afferent neurons ...
Arble, Deanna M., Sandoval, Darleen A.
core   +1 more source

Obesity and Its Impact on Endoscopic Sinus Surgery Outcomes in Patients With Chronic Rhinosinusitis With Nasal Polyps

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Purpose The rising prevalence of obesity introduces challenges in surgical contexts, including endoscopic sinus surgery (ESS) for chronic rhinosinusitis with nasal polyps (CRSwNP). However, the impact of obesity on ESS outcomes remains underexplored. This study aims to evaluate the association between obesity and surgical complexity, operative
Hen Chaushu   +6 more
wiley   +1 more source

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