Results 91 to 100 of about 80,968 (287)

Sleep deprivation aggravates hepatocytes steatosis and insulin resistance by regulating exosomal microRNAs

open access: yesInterdisciplinary Medicine, EarlyView.
Sleep deprivation accelerates the progression of MASLD and IR by up‐regulating the expression of miR‐3572‐5p and down‐regulating the expression of miR‐183‐5p in circulating exosomes, thereby inhibiting fatty acid β‐oxidation and disrupting insulin signaling pathways. Abstract Sleep deprivation (SD) threatens human health and increases the prevalence of 
Xinxin Xu   +10 more
wiley   +1 more source

The effects of leptin on the cardiovascular system [PDF]

open access: yes, 2023
Leptin hormone is an adipokine released from adipose tissue that has recently gained interest due to its impact on the cardiovascular system as well as many other systemic effects.
Kiliç, U.   +3 more
core  

LEPTIN AND OBESITY – NEUROENDOCRINE , METABOLIC AND ATHEROGENIC EFFECTS OF LEPTIN

open access: yesZdravniški Vestnik, 2003
Background. Leptin is an adipocyte-derived hormone that was recently discovered. Leptin and leptin resistance play an important role in the pathogenesis of obesity.
Mišo Šabovič, Alenka Mavri
doaj  

Correlation Analysis of Body Weight with Insulin Resistance and Leptin Levels in Farm Workers

open access: yesJournal of Agromedicine and Medical Sciences (AMS)
Insulin resistance is a pathological condition resulting from impaired insulin response which causes increased insulin production as a form of compensation from pancreatic beta cells. A stable body weight can prevent insulin resistance and excessive body
Naurah Nazihah Azzalina   +2 more
doaj   +1 more source

Leptin resistance: unsolved diagnostic issues

open access: yes, 2018
Leptin and its receptors are key regulators of body weight and energy homeostasis. A decrease in tissue sensitivity to leptin leads to the development of obesity, insulin resistance, dyslipidemia, etc.
Daria A. Borodkina   +5 more
core   +1 more source

Association of Leptin With Obesity and Insulin Resistance

open access: yesCureus, 2020
Introduction Leptin, a hormone released by the body to regulate energy balance by inhibiting hunger, decreases fat storage in adipocytes. Leptin is thought to play some role in obesity and insulin resistance. In this study, our aim is to see the association of leptin with obesity and insulin resistance.
Kumar, Ratan   +8 more
openaire   +2 more sources

Effect of periodontal treatment on adipokines in patients with type 2 diabetes mellitus: A systematic review

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Periodontal disease (PD) is associated with type 2 diabetes mellitus (T2DM), while periodontal treatment (PT) improves glycemic control in T2DM patients. Leptin and adiponectin belong to the adipokines family and have almost antagonistic functions in inflammatory processes and insulin sensitivity modulation.
Natalia Christaki   +3 more
wiley   +1 more source

New pharmacological perspectives for the leptin receptor in the treatment of obesity

open access: yesFrontiers in Endocrinology, 2014
After its discovery in 1994, leptin became the great hope as an anti-obesity treatment based on its ability to reduce food intake and increase energy expenditure.
Clara eRoujeau   +2 more
doaj   +1 more source

Leptin resistance in obesity: An epigenetic landscape

open access: yesLife Sciences, 2015
Leptin is an adipocyte-secreted hormone that inhibits food intake and stimulates energy expenditure through interactions with neuronal pathways in the brain, particularly pathways involving the hypothalamus. Intact functioning of the leptin route is required for body weight and energy homeostasis.
Casanueva Freijo, Felipe   +5 more
openaire   +3 more sources

Biological activities and bioactive constituents of Flammulina velutipes: An updated systematic review

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract Flammulina velutipes (enokitake) is an edible mushroom recognized for both its nutritional and medicinal properties. It exhibits a broad spectrum of biological activities, including antioxidant, anti‐inflammatory, antitumor, immunomodulatory, and gut microbiota‐regulating effects.
Rıdvan Özgen   +2 more
wiley   +1 more source

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