Results 91 to 100 of about 134,529 (291)

Serum leptin changes with metformin treatment in polycystic ovarian syndrome [PDF]

open access: yes, 2011
The relationship between leptin, insulin resistance and other hormonal parameters in polycystic ovarian syndrome (PCOS) is controversial. We investigated the effect of metformin on leptin levels in women with PCOS.
Rehan, H. S.   +2 more
core  

Glucocorticoids as Counterregulatory Hormones of Leptin: Toward an Understanding of Leptin Resistance [PDF]

open access: yesDiabetes, 1997
The product of the ob gene, leptin, is a hormone secreted by adipose tissue that acts in the hypothalamus to regulate the size of the body fat depot. Its central administration has been shown to decrease food intake and body weight, while favoring energy dissipation.
K E, Zakrzewska   +4 more
openaire   +2 more sources

Patient and public involvement in randomized trials of lifestyle intervention among pregnant women with obesity: An umbrella review

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background Obesity increases the risk of obstetric and neonatal complications, and adherence to lifestyle interventions during pregnancy presents a challenge. Patient and public involvement (PPI) in trials may foster a more patient‐centered approach, potentially improving compliance with intervention and follow up.
Elisabeth Garcia Vilaplana   +6 more
wiley   +1 more source

Assessment of Serum Leptin Level and Insulin Resistance in Obese Subjects

open access: yesJournal of Rawalpindi Medical College, 2012
Background: To determine the relationship between serum leptin and insulin resistance in obese Pakistani subjects. Methods: In this observational study fifty healthy obese and overweight subjects were selected by nonprobability convenience sampling. Age,
Ahsan Kazmi
doaj  

Altered leptin signaling and attenuated cardiac vagal activity in rats with type 2 diabetes

open access: yesFrontiers in Physiology
IntroductionThe leading cause of death in type 2 diabetes mellitus (T2DM) patients is cardiovascular-related events, including myocardial infraction-induced ventricular arrhythmia.
Anthony J. Evans   +7 more
doaj   +1 more source

Leptin therapy, insulin sensitivity, and glucose homeostasis

open access: yesIndian Journal of Endocrinology and Metabolism, 2012
Glucose homeostasis is closely regulated not only by insulin, but also by leptin. Both hormones act centrally, regulating food intake and adiposity in humans. Leptin has several effects on the glucose-insulin homeostasis, some of which are independent of
Gilberto Paz-Filho   +3 more
doaj   +1 more source

Adipokines and body fat composition in South Asians: results of the Metabolic Syndrome and Atherosclerosis in South Asians Living in America (MASALA) study. [PDF]

open access: yes, 2012
ObjectiveTo investigate whether leptin and adiponectin are associated with body fat composition in a South Asian population independent of metabolic variables.DesignCross-sectional study.Subjects150 South Asian men and women, between the ages of 45-79 ...
Budoff, MJ   +4 more
core  

Effect of periodontal treatment on adipokines in patients with type 2 diabetes mellitus: A systematic review

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Periodontal disease (PD) is associated with type 2 diabetes mellitus (T2DM), while periodontal treatment (PT) improves glycemic control in T2DM patients. Leptin and adiponectin belong to the adipokines family and have almost antagonistic functions in inflammatory processes and insulin sensitivity modulation.
Natalia Christaki   +3 more
wiley   +1 more source

Hepatocyte-specific HIF-1α ablation improves obesity-induced glucose intolerance by reducing first-pass GLP-1 degradation. [PDF]

open access: yes, 2019
The decrease in incretin effects is an important etiologic component of type 2 diabetes with unknown mechanisms. In an attempt to understand obesity-induced changes in liver oxygen homeostasis, we found that liver HIF-1α expression was increased mainly ...
Bandyopadhyay, Guatam K   +3 more
core  

Biological activities and bioactive constituents of Flammulina velutipes: An updated systematic review

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract Flammulina velutipes (enokitake) is an edible mushroom recognized for both its nutritional and medicinal properties. It exhibits a broad spectrum of biological activities, including antioxidant, anti‐inflammatory, antitumor, immunomodulatory, and gut microbiota‐regulating effects.
Rıdvan Özgen   +2 more
wiley   +1 more source

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