Results 81 to 90 of about 2,304,681 (286)

Leptin-dependent Phosphorylation of PTEN Mediates Actin Restructuring and Activation of ATP-sensitive K+ Channels [PDF]

, 2009
Leptin activates multiple signaling pathways in cells, including the phosphatidylinositol 3-kinase pathway, indicating a degree of cross-talk with insulin signaling. The exact mechanisms by which leptin alters this signaling pathway and how it relates to
Miller, L.C., Sutherland, C., Sutherland, Calum, Gallagher, J., Miller, Lisa C., Ashford, M.L.J., Ning, K., Laidlaw, Hilary A., Watterson, Kenneth R., Sutherland, Calum; id_orcid, Laidlaw, H.A., Ning, Ke, Ashford, Michael L. J.; id_orcid, Watterson, K.R., Gallagher, Jennifer, Ashford, Michael L.J.   +15 more
core   +1 more source

Triglyceride glucose index as a surrogate marker of insulin resistance and its correlation with serum leptin levels in gestational diabetes

National Journal of Physiology, Pharmacy and Pharmacology, 2023
Background: Gestational diabetes mellitus (GDM) is a leading global public health burden affecting up to 12.8% of women. Hyperinsulinemia stimulates adiposity and leptin production.
Niveditha Pari, Viji Devanand, Sampathkumari S, Vasantha Kumar M, Anitha D   +4 more
doaj   +1 more source

Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges

BMEMat, EarlyView.
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma, Nan Jiang, Liyuan Chen, He Zhang, Xinjia Cai, Karan Gulati, Danqing He, Zhigang Cai, Yan Liu   +8 more
wiley   +1 more source

Impact of single nucleotide polymorphisms in leptin, leptin receptor, growth hormone receptor, and diacylglycerol acyltransferase (DGAT1) gene loci on milk production, feed, and body energy traits of UK dairy cows [PDF]

, 2008
The impact of 9 single nucleotide polymorphisms (SNP) in the leptin (LEP), leptin receptor (LEPR), growth hormone receptor (GHR), and diacylglycerol acyltransferase (DGAT1) gene loci on daily milk production, feed intake, and feed conversion, and weekly ...
Woodward, B. W., Forbes, A. B., Coffey, M. P., Banos, G., Woolliams, J. A.   +4 more
core   +1 more source

Association between serum leptin concentrations and insulin resistance: a population-based study from China. [PDF]

PLoS ONE, 2013
BACKGROUND: Insulin resistance contributes to the cardio-metabolic risk. The effect of leptin in obese and overweight population on insulin resistance was seldom reported.
Hui Zuo, Zumin Shi, Baojun Yuan, Yue Dai, Gaolin Wu, Akhtar Hussain   +5 more
doaj   +1 more source

Baseline Body Mass Index Category and Incident Treated Hypertension in Australian Men: A Linked Prospective Cohort Study Using PBS/MBS Data

Chronic Diseases and Translational Medicine, EarlyView.
Kaplan–Meier hypertension‐free survival by baseline body mass index category, primary adult cohort (men aged ≥ 18 years, n = 12,742). Time since baseline in years is plotted on the horizontal axis and the probability of remaining free of treated hypertension is plotted on the vertical axis. Numbers at risk are shown beneath the plot.
Ebenezer Afrifa‐Yamoah
wiley   +1 more source

Corticosterone inhibits the lipid-mobilizing effects of oleoyl-estrone in adrenalectomized rats [PDF]

, 2007
Oleoyl-estrone (OE) is an adipose-derived signal that decreases energy intake and body lipid, maintaining energy expenditure and glycemic homeostasis. Glucocorticoids protect body lipid and the metabolic status quo.
Fernández López, José Antonio, Serrano, Marta, Alemany, Marià, 1946-, Grasa Martínez, Maria del Mar   +3 more
core   +1 more source

Hyperleptinemia in patients with gastroesophageal reflux disease and obesity: approaches to the assessment and prevention of leptin resistance

Gastroenterologìa
Background. Gastroesophageal reflux disease (GERD) and obesity remain the most common comorbid pathology, which significantly affects the deterioration of the quality of life of patients.
Л.М. Мосійчук, О.М. Татарчук, І.А. Кленіна, О.М. Шевцова, О.П. Петішко   +4 more
doaj   +1 more source

Increased Insulin Action, Glucose Metabolism and Muscle Function in Supervillin‐Knockout and Supervillin‐Mutant Mice

Cytoskeleton, EarlyView.
ABSTRACT We here describe mouse models with complementary homozygous Svil mutations. In skeletal muscle, Svil‐Mut mice express the Svil‐encoded N‐terminus fused to the βgal‐neo gene‐trap tag and lack the highly conserved archvillin C‐terminus; Svil‐KO mice lack expression of all known Svil‐encoded proteins; and Svil‐LoxP mice contain loxP sites for ...
Tara C. Smith, Lauren A. Tauer, Randall H. Friedline, Xiaodi Hu, Duy Tran, Yangyi E. Luo, Nacima Hadjout‐Rabi, Elisabeth R. Barton, Jason K. Kim, Elizabeth J. Luna   +9 more
wiley   +1 more source

Increased circulating ANG II and TNF-α represents important risk factors in obese Saudi adults with hypertension irrespective of diabetic status and BMI [PDF]

, 2012
Central adiposity is a significant determinant of obesity-related hypertension risk, which may arise due to the pathogenic inflammatory nature of the abdominal fat depot.
Bindahman, Lotfi S., Mohamed, Amany O., Draz Hossam M., Saleem, Tahia H., Alkharfy Khalid M., Lotfi S Bindahman, Mohamed Amany O., Omar S Al-Attas, Alokail, Majed S., Al-Attas, Omar S., Al-Attas Omar S., Philip G McTernan, Al-Daghri, Nasser M., Tahia H Saleem, Amany O Mohamed, Hossam M Draz, Harte Alison L., Majed S Alokail, Alison L Harte, Saleem Tahia H., Yakout Sobhy, Harte, Alison L., Al-Daghri Nasser M., Alokail Majed S., Nasser M Al-Daghri, McTernan Philip G., Bindahman Lotfi S., Yakout, Sobhy M., Draz, Hossam M., Alkharfy, Khalid M., McTernan, P. G. (Philip G.), Sobhy Yakout, Khalid M Alkharfy   +32 more
core   +2 more sources