Results 151 to 160 of about 2,304,681 (286)
Andrology, EarlyView.ABSTRACT Introduction Direct experimental investigation of Klinefelter syndrome (KS) in patients is limited because the syndrome manifests heterogeneously and affects multiple organ systems. Studying KS therefore requires a model that captures this complexity as accurately as possible while still permitting controlled experimental manipulation ...
Fariba Saadati, Joachim Wistuba
wiley +1 more source
Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?
British Journal of Pharmacology, EarlyView.Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli +7 more
wiley +1 more source
Possible pharmacological role of Leptin medication in pregnancy
, 2021 Through this Thesis I tried to explore the multiple options of using Leptin as a medical tool, I chose to focus on the role of Leptin as a key factor, whose deficiency may impair pregnancy processes, and chose to do my best in arising the awareness of ...
Botchan, Shay Nohar
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CRF1 and ACTH inhibitors are a promising approach to treat obesity and leptin and insulin resistance
Frontiers in EndocrinologyEvidence synthesisObesity is a state of subtle hypercortisolism accompanied by leptin and insulin resistance. Serum total cortisol concentration is normal or slightly subnormal in obese subjects. However, they have high cortisol production rates. Reduced
Patricio H. Contreras +2 more
doaj +1 more source
Impact of incretin analogues on lipid and lipoprotein metabolism in obesity and diabetes
British Journal of Pharmacology, EarlyView.Abstract Incretin‐based therapies have gained momentum as a key strategy for reducing cardiovascular risk in individuals with obesity and/or type 2 diabetes (T2D). It remains unclear whether the cardiovascular benefits reflect a direct reduction in atherogenic lipoproteins—namely, low‐density lipoproteins (LDL), very low‐density lipoproteins (VLDL) and
Andrea Baragetti, Giuseppe Danilo Norata
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AN ECONOMIC ANALYSIS OF GENETIC INFORMATION: LEPTIN GENOTYPING IN FED CATTLE [PDF]
The use of genetic knowledge is widespread in crop production but is just recently being utilized in livestock production. This study investigates the economic value to feedlots of a polymorphism in the bovine leptin gene.
Bullinger, Jared R. +4 more
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Amylin analogues as a novel perspective in anti‐obesity therapy
British Journal of Pharmacology, EarlyView.Abstract Public health systems face a major challenge because of the worldwide obesity epidemic. The number of obese individuals has increased dramatically and, even in Switzerland which may be considered a relatively “lean” country, the numbers are alarmingly high and have reached almost 50% of the adult population.
Thomas A. Lutz
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, 2018 Min Zhang,1 Xiaohong Jiang,2 Meidi Qu,1 Hongliu Gu,1 Qi Sha,1 Fei Hua2 1Department of Clinical Nutrition, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu 213003, China; 2Department of Endocrinology, The Third Affiliated Hospital ...
Gu H +5 more
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Gut microbiota as a novel therapeutic target for eating disorders and obesity
British Journal of Pharmacology, EarlyView.The graphical abstract highlights the bidirectional interaction between the gut microbiota and central homeostatic and hedonic mechanisms regulating food intake, which contributes to overweight and obesity. It also illustrates emerging microbiota‐based biomarkers and therapeutic strategies (including prebiotics, probiotics, postbiotics, synbiotics and ...
Solveiga Samulėnaitė +5 more
wiley +1 more source