Results 221 to 230 of about 72,689 (297)

Cross‐Sectional and Longitudinal Associations of Irisin and Adiponectin With Obesity, Sarcopenia and Sarcopenic Obesity

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Background Irisin, an exercise‐induced myokine and adiponectin, an adipocyte‐derived hormone, are involved in energy metabolism and musculoskeletal health. However, their associations with obesity, abdominal obesity, sarcopenia and sarcopenic obesity remain unclear, and longitudinal evidence is limited.
Yejin Kim, Hong Ji Song, Dong‐Hyun Kim, Jin‐Young Jeong, Kyung Hee Park, Yong Soon Park, Jwa‐Kyung Kim, Hye‐Mi Noh   +7 more
wiley   +1 more source

Inhibition of Plasminogen Activator Inhibitor-1 Activation Suppresses High Fat Diet-Induced Weight Gain via Alleviation of Hypothalamic Leptin Resistance. [PDF]

Front Pharmacol, 2020
Hosaka S, Yamada T, Takahashi K, Dan T, Kaneko K, Kodama S, Asai Y, Munakata Y, Endo A, Sugawara H, Kawana Y, Yamamoto J, Izumi T, Sawada S, Imai J, Miyata T, Katagiri H.   +16 more
europepmc   +1 more source

Age‐Stratified Associations of Sarcopenic Obesity With Mortality in Type 2 Diabetes

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Background Sarcopenic obesity, the coexistence of sarcopenia and obesity, has been linked to adverse health outcomes due to comorbidity. Evidence on the association between sarcopenic obesity and mortality among individuals with Type 2 diabetes remains limited Methods Sarcopenic obesity was defined using Japan Working Group on Sarcopenic ...
Shinta Yamamoto, Yoshitaka Hashimoto, Fuyuko Takahashi, Moe Murai, Nozomi Yoshioka, Yuto Saijyo, Chihiro Munekawa, Hanako Nakajima, Noriyuki Kitagawa, Takafumi Osaka, Ryosuke Sakai, Hiroshi Okada, Naoko Nakanishi, Saori Majima, Emi Ushigome, Masahide Hamaguchi, Michiaki Fukui   +16 more
wiley   +1 more source

Natural Products in Cancer Prevention and Therapy: Current Challenges and Future Directions

MedComm, Volume 7, Issue 2, February 2026.
Natural products play a pivotal role in cancer therapy. They induce cancer cell death by reprogramming four metabolic pathways while precisely targeting the tumor microenvironment and immune cells. These compounds not only leverage novel delivery systems for innovative applications but also demonstrate unique therapeutic efficacy across clinical stages:
Ruimiao Qian, Jun Ge, Ni Fan, Zheng Sun, Chengcheng Zhao, Yujiao Sun, Yingpeng Li, Yunfei Li, Hui Fu   +8 more
wiley   +1 more source

Role of Acid‐Sensing Ion Channels 1a in the Regulation of Obesity and the Gut Microbiota

Obesity, Volume 34, Issue 2, Page 372-381, February 2026.
ABSTRACT Objective Acid‐sensing ion channels are proton‐activated ion channels predominantly found in the nervous system. They are well known to affect metabolic and neurological health, yet their role in obesity and gut physiology remains unclear. This study investigates how systemic deletion of Asic1a influences obesity, metabolic, and gut‐based ...
Jane Shearer, Morris H. Scantlebury, Oghenefejiro Erome‐Utunedi, Anamika Choudhary, Jennifer A. Thompson, Christina Ohland, Kathy D. McCoy, Chunlong Mu   +7 more
wiley   +1 more source

Does elevated bilirubin aid weight control by preventing development of hypothalamic leptin resistance? [PDF]

Open Heart, 2019
DiNicolantonio JJ, McCarty M, OKeefe J.
europepmc   +1 more source

Sex‐Specific Subcutaneous Adipose Tissue Transcriptome in Obesity: Insights From Monozygotic Twin Pairs Discordant for BMI

Obesity, Volume 34, Issue 2, Page 394-406, February 2026.
ABSTRACT Objective We investigated the impact of sex on the subcutaneous adipose tissue (AT) transcriptome and its obesity‐related adaptations. Methods We studied rare BMI‐discordant monozygotic twin pairs (ΔBMI > 2.5 kg/m2; 21 female, 16 male pairs) to assess how sex affects AT and whole‐body metabolism.
Hanna Haltia, Maheswary Muniandy, Sini Heinonen, Sina Saari, Marcus Alvarez, Antti Hakkarainen, Jesper Lundbom, Juho Kuula, Per‐Henrik Groop, Jaakko Kaprio, Päivi Pajukanta, Kirsi H. Pietiläinen, Birgitta W. van der Kolk   +12 more
wiley   +1 more source

Attenuation of Inflammation and Leptin Resistance by Pyrogallol-Phloroglucinol-6,6-Bieckol on in the Brain of Obese Animal Models. [PDF]

Nutrients, 2019
Son M, Oh S, Choi J, Jang JT, Choi CH, Park KY, Son KH, Byun K.   +7 more
europepmc   +1 more source

Obesity and leptin resistance: distinguishing cause from effect

, 2010
Martin G. Myers, Rudolph L. Leibel, Randy J. Seeley, Michael W. Schwartz   +3 more
openalex   +2 more sources