Results 211 to 220 of about 80,968 (287)

Independent and synergistic effects of maternal and paternal obesogenic diets on offspring early‐life outcomes in the rat

open access: yesExperimental Physiology, EarlyView.
Abstract Independent effects of maternal obesogenic diets on offspring outcomes are acknowledged, but data on paternal and combined maternal–paternal obesity remain limited. We investigated independent and combined maternal–paternal effects of an obesogenic (OB) high‐fat, high‐sugar diet on offspring outcomes.
Khurram Jahangir Toor   +8 more
wiley   +1 more source

Sex‐specific metabolic responses to glucagon receptor agonism and modulation of the FGF21‐glucagon axis in female mice

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Therapies targeting the glucagon receptor are being explored for obesity treatment, yet most preclinical studies remain male biased. In this study, Merrild and Johansen et al. show that in diet‐induced obese wild‐type mice a long‐acting glucagon analogue (LA‐Gcg) elicits sexually dimorphic effects on weight loss, food intake ...
Christoffer Merrild   +3 more
wiley   +1 more source

Sam68 mediates leptin signaling and action in human granulosa cells: possible role in leptin resistance in PCOS. [PDF]

open access: yesEndocr Connect, 2020
Vilariño-García T   +5 more
europepmc   +1 more source

Reduced cardiovascular mortality at moderate altitude: a putative role of physical activity and body mass

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Benefits of performing physical exercise at moderate altitude. At moderate altitude, increased resting metabolic rate and physical exertion promote physical fitness and exercise tolerance, whereas hypoxia suppresses appetite and elicits adaptations that increase tissue O2 delivery while augmenting O2‐independent ATP production ...
Robert T. Mallet   +6 more
wiley   +1 more source

Δ9 Tetrahydrocannabinol and cannabis extracts differentially improve adipoinsular dysfunction in diet‐induced obesity

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend THC and extract administered to diet‐induced obese mice reduced body weight and fat storage. Extract, but not THC, improved glucose clearance by a mechanism that may include restoring adipoinsular function. Abstract Diet‐induced obesity (DIO) is associated with dysregulated adipoinsular axis and endocannabinoid system (eCBS ...
Bryant Avalos   +7 more
wiley   +1 more source

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