Results 221 to 230 of about 134,529 (291)

Reading hominin life history in fossil bones and teeth: methods to test hypotheses regarding its evolution

open access: yesBiological Reviews, Volume 101, Issue 3, Page 1463-1478, June 2026.
ABSTRACT Human life history is derived compared to that of our closest living relatives, the great apes. It has been suggested that these derived traits are causally related to aspects of our ecology, social behaviour and cognitive abilities. However, resolving this requires that we know the evolutionary trajectory of our distinctive pattern of growth,
Paola Cerrito   +2 more
wiley   +1 more source

Associations Between Serum Adipokine, Antipsychotic Exposure, and Clinical Characteristics in Chronic Schizophrenia: A Cross‐Sectional Study

open access: yesNeuropsychopharmacology Reports, Volume 46, Issue 2, June 2026.
In chronic schizophrenia, serum adiponectin levels were positively associated with antipsychotic dosage, particularly with multi‐acting receptor‐targeted antipsychotics and were influenced by gender and hospitalization period. These findings highlight gender‐specific metabolic regulation and the importance of monitoring adipokines during long‐term ...
Yasuhiro Ohno   +6 more
wiley   +1 more source

Aerobic Exercise Plus Hypocaloric Diet on Serum Leptin Concentrations in Adults With Primary Hypertension and Overweight/Obesity: Results From the EXERDIET‐HTA Trial

open access: yesClinical Obesity, Volume 16, Issue 3, June 2026.
Aerobic exercise plus hypocaloric diet on serum leptin concentrations in adults with primary hypertension and Overweight/Obesity. ABSTRACT Hyperleptinaemia is an emerging mechanism involved in the pathogenesis of obesity‐related primary hypertension (HTN).
Virginia A. Aparicio   +4 more
wiley   +1 more source

SemaGBA: A System Dynamics Model of the Semaglutide‐Responsive Gut‐Brain Axis A Model of How the Brain and Semaglutide Regulate Appetite and Weight

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 6, Page 5184-5194, June 2026.
ABSTRACT Aims Semaglutide is a GLP‐1 receptor agonist for the treatment of type 2 diabetes and obesity. Its clinical effects are well established, but the underlying mechanisms remain unclear. This study aims to use computational modelling to generate hypotheses about semaglutide's long‐term metabolic (body weight, net energy intake, blood glucose ...
Vivan C. W. Kennis, Natal A. W. van Riel
wiley   +1 more source

Distinct Roles of Myeloid‐ and Hepatocyte‐PLA2G6 Deletion in Mice With Metabolic Dysfunction‐Associated Steatotic Liver Disease

open access: yesLiver International, Volume 46, Issue 6, June 2026.
ABSTRACT Background and Aims Polymorphisms of group VIA calcium‐independent phospholipase A2 (iPLA2β or PLA2G6) are associated with Type‐2 diabetes, blood lipids and inflammation. Global deficiency in iPLA2β‐null mice elicited protection against hepatic steatosis but not hepatic inflammation after high‐fat diet (HFD) feeding.
Gang Li   +4 more
wiley   +1 more source

Metabolic Syndrome and Obesity‐related cancer Risk and Survival: An Umbrella Review of Systematic Reviews With Meta‐analysis of Observational Studies

open access: yesObesity Reviews, Volume 27, Issue 6, June 2026.
ABSTRACT Introduction Metabolic syndrome (MetS) may be associated with obesity‐related cancer (ORC) owing to shared risk factors like physical inactivity, insulin resistance, gut microbiome dysfunction, and inflammation. We conducted an umbrella review of systematic reviews with meta‐analysis to synthesize the evidence on the association between MetS ...
Maci Winn   +13 more
wiley   +1 more source

Effects of Intermittent Fasting‐Mimicking Diet on Pancreatic Islet Plasticity: Immunohistochemical, Ultrastructural, and Metabolic Profiles

open access: yesThe FASEB Journal, Volume 40, Issue 9, 15 May 2026.
Three weeks of fasting‐mimicking diet in female C57BL/6J mice increased pancreatic BNR4+ cells, PDX1+BRN4+ cells and insulin+glucagon+ cells after fasting in fluorescent multiplexed immunohistochemistry. Mice showed impaired glucose tolerance after fasting but not after refeeding after 2 weeks.
Clemens M. Harer   +13 more
wiley   +1 more source

Periodontitis in Patients With Severe Obesity: From the Oral and Gut Microbiota Dysregulation to the Visceral Adipose Tissue Inflammatory and Metabolic Disorders

open access: yesThe FASEB Journal, Volume 40, Issue 9, 15 May 2026.
In patients with severe obesity, periodontitis is associated with oral microbiota dysbiosis which influences gut microbiota composition by increasing Proteobacteria proportion. These alterations are linked to systemic immune and metabolic changes, including higher circulating levels of anti‐Porphyromonas gingivalis lgG and deregulated lipid profile ...
Katy Thouvenot   +11 more
wiley   +1 more source

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