Results 221 to 230 of about 80,968 (287)
The Journal of Physiology, EarlyView.Abstract figure legend Central leptin signalling blockade induces early metabolic dysfunction. Intracerebroventricular infusion of a leptin receptor antagonist (SLA) in rats disrupts hypothalamic leptin signalling, leading to reduced signal transducer and activator of transcription 3 (STAT3) activation, decreased Socs3 and Pomc expression, and ...
Cristina Pintado +16 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Acute aerobic exercise induces LGALS1, FSTL1, OGN and C1QTNF3 in both skeletal muscle and adipose tissue, with LGALS1 and FSTL1 upregulation corresponding to increased circulating galectin‐1 and follistain‐like 1. Red and yellow brick bars represent the contribution of skeletal muscle and adipose tissue, respectively, integrating
Jaeseung Song +5 more
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Endocrinology, Diabetes &Metabolism, Volume 9, Issue 4, July 2026.This article systematically reviews how insulin resistance (IR) disrupts endometrial receptivity by interfering with glucose metabolism mechanisms, ultimately leading to infertility in patients with Polycystic Ovary Syndrome (PCOS). ABSTRACT Introduction Insulin resistance (IR) is one of the important pathologic bases of polycystic ovary syndrome (PCOS)
Si‐yan Huang +7 more
wiley +1 more source
Food Frontiers, Volume 7, Issue 4, July 2026.Soybean‐derived exosome‐like nanovesicles suppress lipid accumulation of adipocytes via UCP1/PGC‐1α mediated thermogenesis pathway and boosting mitochondrial function. ABSTRACT Obesity has become an important public health concern in modern society. Plant‐derived exosome‐like nanovesicles are emerging as candidates for obesity intervention.
Zhenzhu Zhu +5 more
wiley +1 more source
Dynamics of Apolipoprotein J Levels and Metabolic Parameters Following Bariatric Surgery
Clinical Endocrinology, Volume 105, Issue 1, Page 42-50, July 2026.ABSTRACT Objective Bariatric surgery has emerged as a potent intervention for ameliorating insulin resistance and its associated comorbidities in obese patients. Apolipoprotein J (ApoJ) and adiponectin are closely associated with insulin resistance and sensitivity, respectively.
Kellen Cristina da Cruz Rodrigues +7 more
wiley +1 more source
Diabetes, Obesity and Metabolism, Volume 28, Issue 7, Page 5751-5760, July 2026.ABSTRACT Aims Cardiovascular diseases (CVD) are the leading cause of death worldwide, with excess visceral adipose tissue (VAT) being identified as an independent indicator of poor cardiovascular outcomes. We examined the association between three indices of VAT, namely, metabolic score for visceral fat (METS‐VF), visceral adiposity index (VAI), and ...
A‐Ra Cho +3 more
wiley +1 more source
Diabetes, Obesity and Metabolism, Volume 28, Issue 7, Page 5810-5826, July 2026.ABSTRACT Aims Cold exposure activates brown adipose tissue (BAT) and promotes thermogenic and metabolic adaptations. While BAT activation has been linked to improved cardiometabolic health, how acute cold exposure reshapes the circulating lipidome in humans remains incompletely understood.
Yu Zhang +7 more
wiley +1 more source
Hyperaldosteronism in the Pathophysiology and Management of Cardiovascular‐Kidney‐Metabolic Syndrome
Diabetes, Obesity and Metabolism, Volume 28, Issue 7, Page 5463-5475, July 2026.ABSTRACT Cardiovascular‐kidney‐metabolic (CKM) syndrome is defined by the pathologic interconnections between obesity, diabetes, chronic kidney disease and cardiovascular disease. An important and underrecognized pathophysiologic factor underlying CKM syndrome is obesity‐induced aldosterone excess.
Evan Zeitler +4 more
wiley +1 more source
Does elevated bilirubin aid weight control by preventing development of hypothalamic leptin resistance? [PDF]
Open Heart, 2019 DiNicolantonio JJ, McCarty M, OKeefe J.
europepmc +1 more source