Results 201 to 210 of about 2,304,681 (286)

Inflammatory mediator contributes to leptin resistance and obesity in craniopharyngioma. [PDF]

FASEB J
Xiao Y, Wu W, Liu F, Jin L, Jia Y, Qiao N, Cai K, Ru S, Cao L, Gui S.   +9 more
europepmc   +1 more source

Epigenomic Cascades Across Organs in Metabolic Dysfunction–Associated Steatotic Liver Disease: New Therapeutic Horizons

Obesity Reviews, EarlyView.
ABSTRACT Metabolic dysfunction–associated steatotic liver disease (MASLD) is the most common chronic liver disorder worldwide, affecting approximately one‐third of the population and increasing the risk of severe hepatic and cardiovascular complications.
Shurui Yang, Zhongyu Huang, Sanchun Tan, Fengxia Liang, Li Chen   +4 more
wiley   +1 more source

Skeletal glucocorticoid signalling determines leptin resistance and obesity in aging mice. [PDF]

Mol Metab, 2020
Henneicke H, Kim S, Swarbrick MM, Li J, Gasparini SJ, Thai J, Foong D, Cavanagh LL, Fong-Yee C, Karsten E, Lin RCY, Cooper MS, Zhou H, Seibel MJ.   +13 more
europepmc   +1 more source

Microbiome and Metabolomics in Obesity: Advances in Understanding and Interventions Across the Lifespan

Obesity Reviews, EarlyView.
ABSTRACT Obesity arises from intertwined and reciprocal diet‐microbiome‐host pathways that reshape energy balance, insulin sensitivity, and inflammation. This review synthesizes mechanistic links between microbial functions and metabolic control, charts lifestyle‐related lifecourse dynamics from birth to older age, examines how GLP‐1‐based therapies ...
Ioanna Panagiota Kalafati, David Krongauz, Alice Bosco, Antonio Noto, Cristina Piras, Maria Kafyra, Angelica Dessì, Matteo Mauri, Luigi Atzori, Adina Weinberger, Vassilios Fanos, George V. Dedoussis, on behalf of the BETTER4U consortium   +12 more
wiley   +1 more source

Correction: Therapeutic target analysis and molecular mechanism of melatonin-treated leptin resistance induced obesity: a systematic study of network pharmacology. [PDF]

Front Endocrinol (Lausanne)
Suriyagandhi V, Nachiappan V.
europepmc   +1 more source

Investigating Overweight and Obesity Risk in Shift Workers Using Omics Technologies

Obesity Reviews, EarlyView.
ABSTRACT Night shift workers are at higher risk of developing overweight and obesity. The disruption of the physiological circadian rhythm leads to metabolic alterations, such as decreased insulin sensitivity, increased adipogenesis, and inflammation, with effects on their health and leading, among other diseases, to obesity.
Katrin Scionti, Ivana Václavková, Vanessa Schoissengeier, Karl‐Heinz Wagner   +3 more
wiley   +1 more source

Dexamethasone-induced whitening of rabbit brown adipose tissue: leptin resistance and mitochondrial dysfunction. [PDF]

BMC Genomics
Tang X, Zhang B, Xie P, Wei Y, Qiu Y, Yi X, Zhang Z, She M, Sun X, Wang S.   +9 more
europepmc   +1 more source

Osteolectin/CLEC11A‐Related Signaling Molecules in Periodontitis and Peri‐Implantitis

Oral Diseases, EarlyView.
ABSTRACT Objective Periodontal and peri‐implant tissues differ histologically and biomechanically, which may be reflected in local osteogenic and mechanosensitive signaling. This exploratory cross‐sectional study aimed to compare expression profiles of Osteolectin (CLEC11A) and related signaling molecules across periodontal health, peri‐implant health,
Gözde Işıker Kara, Feyzanur Caldiran, Hatice Balci Yuce, Busenur Sahin, Ercan Cacan   +4 more
wiley   +1 more source

Leptin Resistance and Cardiometabolic Disorders: Bridging Molecular Pathways, Genetic Variants, and Therapeutic Innovation. [PDF]

Curr Cardiol Rev
Roy P, Kant R, Kaur A, Kumar H, Kumar R.
europepmc   +1 more source

Frozen Shoulder as a Metabolic and Immune Disorder: Potential Roles of Leptin Resistance, JAK-STAT Dysregulation, and Fibrosis. [PDF]

J Clin Med
Navarro-Ledesma S.
europepmc   +1 more source