Results 231 to 240 of about 80,968 (287)
ABSTRACT Background Metabolic dysfunction‐associated steatotic liver disease (MASLD) increases cardiovascular and kidney disease risk. Insulin‐like growth factor 1 (IGF‐1) regulates metabolic and vascular function, but its role in long‐term cardio‐kidney outcomes (CKO) in MASLD remains unclear.
Yongin Cho +4 more
wiley +1 more source
Attenuation of Inflammation and Leptin Resistance by Pyrogallol-Phloroglucinol-6,6-Bieckol on in the Brain of Obese Animal Models. [PDF]
Son M +7 more
europepmc +1 more source
Postprandial Glucagon Action in the Human Brain
ABSTRACT Aims Elevated fasting glucagon is linked to hyperglycemia, but postprandial glucagon effects are less understood. Recent evidence suggests metabolic benefits of rising glucagon after oral glucose intake, potentially impacting brain‐mediated whole‐body metabolism.
Robert Wagner +11 more
wiley +1 more source
Removing melatonin receptor type 1 signaling leads to selective leptin resistance in the arcuate nucleus. [PDF]
Buonfiglio D +6 more
europepmc +1 more source
ABSTRACT In a scenario with increasing cases of obesity and diabetes worldwide, branched‐chain amino acids (BCAA) metabolism has become an important factor in the understanding of these pathologies. More recently, its chronic high plasma levels have been postulated, alongside glucose, inflammatory factors, and other molecules, as an important ...
Bernardo Starling‐Soares +4 more
wiley +1 more source
Agrp-Specific Ablation of Scly Protects against Diet-Induced Obesity and Leptin Resistance. [PDF]
Torres DJ +3 more
europepmc +1 more source
ABSTRACT Obesity as a chronic and multifactorial disease requires a multidisciplinary team acting together in a holistic multitarget intervention. Multidisciplinary therapy targeting obesity and its complications includes physical exercise, nutritional, and behavior counseling.
Ana Raimunda Dâmaso +7 more
wiley +1 more source
Maternal Obesity and MicroRNAs in Breast Milk: Implications for Infant Developmental Programming
ABSTRACT This review explores the relationship between maternal obesity and alterations in the expression of microRNAs (miRNAs) in breast milk, highlighting how these changes may influence the developmental programming of the infant. Evidence suggests that maternal obesity can affect the bioactive composition of breast milk, including miRNA profiles ...
Gyslane M. Santos +2 more
wiley +1 more source
We demonstrate that Cars2, a cysteine catabolic enzyme in mouse iBAT, is critical for cold tolerance and brown adipocyte differentiation. Through its CPERS activity, Cars2 produces CysSSH/H2S to induce EBF2 persulfidation, promoting its interaction with PPARγ and BRG1 to enhance thermogenic gene expression.
Xin Peng +8 more
wiley +1 more source
Hypothalamic‐Pituitary‐Testicular Axis Regulation in Men With Type 2 Diabetes
Clinical Endocrinology, Volume 105, Issue 1, Page 22-23, July 2026.
Mathis Grossmann
wiley +1 more source

