Results 231 to 240 of about 74,494 (249)

Improvement of Leptin Resistance

Yeungnam University Journal of Medicine, 2013
Leptin, a 16-kDa cytokine, is secreted by adipose tissue in response to the surplus of fat store. Thereby, the brain is informed about the body's energy status. In the hypothalamus, leptin triggers specific neuronal subpopulations (e.g., POMC and NPY neurons) and activates several intracellular signaling events, including the JAK/STAT, MAPK, PI3K, and ...
openaire   +1 more source

Leptin signaling in the hypothalamus: emphasis on energy homeostasis and leptin resistance

Frontiers in Neuroendocrinology, 2003
Leptin, the long-sought satiety factor of adipocytes origin, has emerged as one of the major signals that relay the status of fat stores to the hypothalamus and plays a significant role in energy homeostasis. Understanding the mechanisms of leptin signaling in the hypothalamus during normal and pathological conditions, such as obesity, has been the ...
openaire   +2 more sources

[Insulin resistance, role of leptin and leptin receptor].

Nihon rinsho. Japanese journal of clinical medicine, 2000
Leptin, the obese gene product, is an adipocyte-derived satiety factor which is involved in the regulation of food intake and energy expenditure. Obesity often accompanies insulin resistance and high levels of leptin. In in vitro studies, leptin has been reported to increase fatty acid oxidation and decrease fatty acid synthesis in adipocytes and ...
M, Shintani, Y, Ogawa, K, Nakao
openaire   +1 more source

Central and peripheral leptin resistance in obesity and improvements of exercise

Hormones and Behavior, 2021
Xiaohui Wang
exaly  

Leptin, Adiponectin, and Insulin Resistance

Angiology, 2011
Maria, Sarigianni, Apostolos, Tsapas, Konstantinos, Paletas   +2 more
openaire   +2 more sources

Leptin Resistance and Obesity

2014
Leptin direnci ve obezite leptin reseptörlerinde düşme, maximal leptin sinyal kapasitesi ve diyetle indükte obeziteye duyarlılıktaki artış ile belirmektedir. Öz de artan leptinin obeziteye katkısı leptin direncine dayanmaktadır. Leptin direnci daha fazla obezite ile yıkıcı bir döngüye dönüşmektedir.
openaire   +1 more source

<p>Leptin resistance: underlying mechanisms and diagnosis</p>

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, 2019
Olga Barbarash, Daria Borodkina, Yulia Dyleva   +2 more
exaly  

Decreased cerebrospinal-fluid/serum leptin ratio in obesity: a possible mechanism for leptin resistance

Lancet, The, 1996
R V Considine, Jerzy W Kolaczynski, M R Nyce   +2 more
exaly  

Partial leptin deficiency confers resistance to diet-induced obesity in mice

Molecular Metabolism, 2020
Leon Straub, Zhuzhen Zhang, Joel Elmquist   +2 more
exaly  

Advances in understanding the interrelations between leptin resistance and obesity

Physiology and Behavior, 2014
Zhengquan Su, Jiao Guo
exaly