Results 51 to 60 of about 3,112,452 (367)
Effects of physical exercise on adiponectin, leptin, and inflammatory markers in childhood obesity: systematic review and meta-analysis [PDF]
, 2018 Background: New findings on adipose tissue physiology and obesity-Associated inflammation status suggest that modification of the adipokine level can be relevant for the long-Term prevention of obesity-Associated chronic disease. Objectives: The scope of
Bianco, Antonio +7 more
core +2 more sources
Psychiatry and Clinical Neurosciences, 2019 The associations of serum leptin/soluble leptin receptor (sObR) and leptin resistance with symptoms of depression and anxiety were investigated in patients with type 2 diabetes (T2D).
S. Cernea +4 more
semanticscholar +1 more source
The Role of SOCS-3 in Leptin Signaling and Leptin Resistance [PDF]
Journal of Biological Chemistry, 1999 We earlier demonstrated that leptin induces expression of SOCS-3 mRNA in the hypothalamus. Furthermore, transfection data suggest that SOCS-3 is an inhibitor of leptin signaling. However, little is known about the regulation of SOCS-3 expression by leptin and the mechanism by which SOCS-3 inhibits leptin action.
Karim El-Haschimi +3 more
openaire +3 more sources
Mass spectrometry in ocular drug research
Mass Spectrometry Reviews, EarlyView., 2023 Abstract Mass spectrometry (MS) has been proven as an excellent tool in ocular drug research allowing analyzes from small samples and low concentrations. This review begins with a short introduction to eye physiology and ocular pharmacokinetics and the relevance of advancing ophthalmic treatments.
Eva M. del Amo +6 more
wiley +1 more source
Obesity Induces Hypothalamic Endoplasmic Reticulum Stress and Impairs Proopiomelanocortin (POMC) Post-translational Processing [PDF]
, 2013 It was shown previously that abnormal prohormone processing or inactive proconverting enzymes that are responsible for this processing cause profound obesity.
Cakir, Isin +6 more
core +1 more source
Association of 25 (OH) Vitamin D and leptin in individuals with insulin resistance
Indian Journal of Endocrinology and Metabolism, 2022 Introduction: Asian-Indian individuals with diabetes have been shown to have low vitamin D levels. Whether this hypovitamonisis D is associated with hyperleptinaemia is unclear.
S V Madhu +4 more
doaj +1 more source
The complex interactions between obesity, metabolism and the brain [PDF]
, 2019 Obesity is increasing at unprecedented levels globally, and the overall impact ofobesity on the various organ systems of the body is only beginning to be fullyappreciated. Because of the myriad of direct and indirect effects of obesity causingdysfunction
Keller, Jeffrey Neil +1 more
core +1 more source
Endocrinology, 2019 During pregnancy, when both food intake and circulating leptin concentrations increase, the brain becomes insensitive to leptin. The mechanism by which central leptin resistance during pregnancy emerges remains poorly understood.
Papillon Gustafson +2 more
semanticscholar +1 more source
Influence of leptin on arterial distensibility - A novel link between obesity and cardiovascular disease? [PDF]
, 2002 Background-The mechanisms by which obesity increases the risk of atherosclerotic cardiovascular disease (CVD) are poorly understood. In experimental models, leptin, a hormone produced by adipose tissue, has been shown adversely to affect vascular health.
Cole, TJ +7 more
core +1 more source
Effect of obesity and serum leptin level on clopidogrel resistance
Türk Kardiyoloji Derneği Arşivi, 2016 Objective: Clopidogrel inhibits platelet aggregation by blockade of platelet adenosine diphosphate (ADP) P2Y12 receptor. Leptin is the obesity gene product, and its serum level increases with obesity.
Ali Dogan +5 more
doaj +1 more source