Results 61 to 70 of about 731,605 (329)

Determination of Lethal Dose (LD50) of Venom of four Different Poisonous Snakes found in Pakistan

open access: yes, 2017
Pakistan is the highly fertile region for the envenoming and deadly snakes. The envenoming fatality and snake bite cases are increasing day by day not only in Pakistan but also in World.
G. Parveen   +4 more
semanticscholar   +1 more source

How much nicotine kills a human? Tracing back the generally accepted lethal dose to dubious self-experiments in the nineteenth century

open access: yesArchives of Toxicology, 2013
The human toxicity of nicotine has become increasingly relevant in the past couple of years through marketing of new nicotine-containing products, such as smokeless tobacco and liquids for electronic nicotine delivery systems (electronic cigarettes) that
B. Mayer
semanticscholar   +1 more source

Determination of Median Lethal Dose of Combination of Endosulfan and Cypermethrin in Wistar Rat

open access: yesToxicology International, 2013
The present study was designed to determine the lethal dose 50 (LD 50 ) of combination of cypermethrin, a pyrethroid, and endosulfan, an organochlorine compound in Wistar rats. LD 50 is the amount (dose) of a chemical, calculated as per the concentration
Jaya Raj   +4 more
semanticscholar   +1 more source

Renormalization of radiobiological response functions by energy loss fluctuations and complexities in chromosome aberration induction: deactivation theory for proton therapy from cells to tumor control

open access: yes, 2019
We employ a multi-scale mechanistic approach to investigate radiation induced cell toxicities and deactivation mechanisms as a function of linear energy transfer in hadron therapy.
Abolfath, Ramin   +5 more
core   +1 more source

Frequency analysis of cytolytic T lymphocyte precursors (CTL-P) generated in vivo during lethal rabies infection of mice. II. Rabies virus genus specificity of CTL-P [PDF]

open access: yes, 1984
Cytolytic T lymphocyte precursors (CTL-P) were sensitized in vivo by intraplantar infection of C57BL/6 mice with a lethal dose of rabies virus, strain ERA (ERA).
Aden   +22 more
core   +1 more source

Lassa antiviral LHF-535 protects guinea pigs from lethal challenge

open access: yesScientific Reports, 2022
LHF-535 is a small molecule antiviral currently in development for the treatment of Lassa fever, a zoonotic disease endemic in West Africa that generates significant morbidity and mortality.
Kathleen A. Cashman   +8 more
doaj   +1 more source

Lymphatic involution and early mortality in the young chicken produced by 2.2 GeV protons [PDF]

open access: yes, 1972
Young single-comb white Leghorn cockerels were subjected to single acute doses of either 2.2 GeV protons or 250 kVp X-rays. Since young chickens exposed in the lethal range die within 48 hours of exposure, an hourly tabulation of deaths was recorded for ...
Montour, J. L., Shellabarger, C. J.
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

The acute toxicity of 5-thio-substituted 3-(5-bromofuran-2-yl)-4-ethyl-(4H)-1,2,4-triazole derivatives

open access: yesAktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2015
Aim. Research of the acute toxicity of new compounds could prevent the development of compounds with high pharmacological activity, which exhibit undesirable pharmacological properties.
E. S. Pruglo   +2 more
doaj   +1 more source

Senescence in vitro and ionising radiations—the human diploid fibroblast model [PDF]

open access: yes, 1981
The influence of ionising radiations on ageing is still controversial. Since Hayflick established the concept that diploid cells have finite lifespan in vitro, human diploid fibroblast (HDF) cultures have been recognised as a potent experimental model ...
A.F.G. Stevenson   +44 more
core   +1 more source

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