Guinea pigs sublethally infected with aerosolized Legionella pneumophila develop humoral and cell-mediated immune responses and are protected against lethal aerosol challenge. A model for studying host defense against lung infections caused by intracellular pathogens. [PDF]
, 1987 We have employed the guinea pig model of L. pneumophila infection, which mimics Legionnaires' disease in humans both clinically and pathologically, to study humoral and cell-mediated immune responses to L.
Breiman, RF, Horwitz, MA
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The dose makes the poison: have “field realistic” rates of exposure of bees to neonicotinoid insecticides been overestimated in laboratory studies? [PDF]
, 2014 Recent laboratory based studies have demonstrated adverse sub-lethal effects of neonicotinoid insecticides on honey bees and bumble bees, and these studies have been influential in leading to a European Union moratorium on the use of three neonicotinoids,
BARON G L +16 more
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Resistance risk assessment of the novel complex II inhibitor pyflubumide in the polyphagous pest Tetranychus urticae [PDF]
, 2020 Pyflubumide is a novel selective carboxanilide acaricide that inhibits mitochondrial complex II of spider mite species such as Tetranychus urticae. We explored the baseline toxicity and potential cross-resistance risk of pyflubumide in a reference panel ...
Fotoukkiaii, Seyedeh Masoumeh +3 more
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Cloned defective interfering influenza virus protects ferrets from pandemic 2009 influenza A virus and allows protective immunity to be established [PDF]
, 2012 Influenza A viruses are a major cause of morbidity and mortality in the human population, causing epidemics in the winter, and occasional worldwide pandemics.
Carroll, Miles W. +9 more
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Fisheries and Aquatic SciencesChannel catfish (Ictalurus punctatus), an introduced species in Vietnam, is widely cultured in the Northern provinces. The off-white grub disease in Channel catfish, caused by metacercariae of Dollfustrema bagarii (Digenea: Bucephalidae) lodged in ...
Manh Duc Vu +7 more
doaj +1 more source
Two Genetically Similar H9N2 Influenza A Viruses Show Different Pathogenicity in Mice
Frontiers in Microbiology, 2016 H9N2 Avian influenza virus has repeatedly infected humans and other mammals, which highlights the need to determine the pathogenicity and the corresponding mechanism of this virus for mammals. In this study, we found two H9N2 viruses with similar genetic
Qingtao Liu +7 more
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A synthetic-lethality RNAi screen reveals an ERK-mTOR co-targeting pro-apoptotic switch in PIK3CA+ oral cancers. [PDF]
, 2016 mTOR inhibition has emerged as a promising strategy for head and neck squamous cell carcinomas (HNSCC) treatment. However, most targeted therapies ultimately develop resistance due to the activation of adaptive survival signaling mechanisms limiting the ...
Amornphimoltham, Panomwat +10 more
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, 2012 It is well established that IFN-γ is required for the development of experimental cerebral malaria (ECM) during Plasmodium berghei ANKA infection of C57BL/6 mice. However, the temporal and tissue-specific cellular sources of IFN-γ during P.
Blount, Daniel G +10 more
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Identifying Optimum Herbicide Mixtures to Manage and Avoid Fenoxaprop-p-Ethyl Resistant Phalaris minor in Wheat [PDF]
Planta Daninha, 2016 Use of herbicide mixtures has been advocated as most effective strategy for avoidance and management of herbicide resistant weeds. Effect of twelve selected treatments of four herbicides (clodinafop-propargil, metribuzin, pinoxaden and sulfosulfuron) two-
T. ABBAS +3 more
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Review of the methods to determine the hazard and toxicity of pesticides to bumblebees [PDF]
, 2001 Methods to determine the impact of pesticides on bumblebees are described. They are classified into laboratory tests to determine the acute toxicity and the hazard to bumblebees, (semi) field tests, and brood tests.
Steen, J.J.M., van der
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