Results 71 to 80 of about 35,647 (293)
Gut Medicine, EarlyView.ABSTRACT Postoperative ileus (POI) is a frequent complication after surgical procedures, predominantly manifesting as aberrant gastrointestinal motility, which markedly extends the duration of postoperative recovery for patients. The clinical duration of POI is typically modulated by intricate inflammatory cascades, with mast cells assuming a critical ...
Tian‐le Zhang +4 more
wiley +1 more source
Lipoxygenase pathways in Homo neanderthalensis: functional comparison with Homo sapiens isoforms
Journal of Lipid Research, 2013 Lipoxygenases (LOX) have been implicated in biosynthesis of pro- and anti-inflammatory mediators, and a previous report suggested compromised leukotriene signaling in H. neanderthalensis.
Pavlos Chaitidis +5 more
doaj +1 more source
Health Care Science, EarlyView.Using ARIMA‐based interrupted time‐series analysis, this study reveals that China's NVBP policy significantly reduced daily costs and enhanced affordability, driving generic substitution and the elimination of low‐quality products. Additionally, non‐winning manufacturers adopted strategic pricing behaviors to segment the market.
Yufei Cheng +6 more
wiley +1 more source
Eicosanoid Control Over Antigen Presenting Cells in Asthma
Frontiers in Immunology, 2018 Asthma is a common lung disease affecting 300 million people worldwide. Allergic asthma is recognized as a prototypical Th2 disorder, orchestrated by an aberrant adaptive CD4+ T helper (Th2/Th17) cell immune response against airborne allergens, that ...
Nincy Debeuf +4 more
doaj +1 more source
12: Clinical Aspects of Prostaglandins and Leukotrienes in Migraine
, 1986 Clinical, pathophysiological, pharmacological, and biochemical evidence support the concept that the prostanoid system may be involved in migraine. As a local defence system prostaglandins may best be linked with hyperalgesia and vascular events.
J Parantainen, H Vapaatalo, E Hokkanen
core +1 more source
A current review on animal models of anti-asthmatic drugs screening
Frontiers in PharmacologyAsthma is a chronic inflammatory respiratory condition characterised by airway constriction, smooth muscle spasm, and severe morbidity. It affects around 300 million people globally, with children being especially vulnerable. Despite its worldwide effect,
Shivam Singh +5 more
doaj +1 more source
Unmasking the role of mast cells in dengue
eLife, 2013 Immune cells called mast cells can hinder rather than help the body's response to dengue virus, which suggests that mast cell products could be used as biomarkers to identify severe forms of the disease.
Panisadee Avirutnan +1 more
doaj +1 more source
, 2013 Ibrahim M El-Akkary,1 Zeinat Abdel-Fatah El-Khouly,2 Mervat El-Sayed El-Seweify,1 Gihan A El-Batouti,3 Ekhlas Abdel Aziz,2 Abdelnasser I Adam1 1Department of Human Physiology, 2Department of Applied Medical Chemistry, Medical Research Institute ...
El-Khouly ZA +5 more
core
Frontiers in Medicine, 2017 Cysteinyl leukotrienes (cysLTs), LTC4, and its extracellular metabolites, LTD4 and LTE4, have varied and multiple roles in mediating eosinophilic disorders including host defense against parasitic helminthes and allergic inflammation, especially in the ...
Glaucia A. Thompson-Souza +2 more
doaj +1 more source
Significance of production of peptide leukotrienes in murine traumatic shock
, 1986 We studied the formation of a leukotriene metabolite in plasma and bile during traumatic shock. Anesthetized rats subjected to Noble-Collip drum trauma developed a lethal shock state characterized by a survival time of 1.9 +/- 0.3 h, a 4.5-fold increase
D. J. Lefer +3 more
core +1 more source